Pregnant after IF

Betas were doubling and now they're not

edited October 2014 in Pregnant after IF
Hi ladies. So i know my clinic is being hyper vigilant with me and they are having me come in a lot for bloodwork and ultrasound. Which was great, but now I'm freaking out.

My betas doubled the first 3 draws but my fourth draw they did not. I was at 2470 at 5w and then 96 hours later at 5w4d they were only 3730. I know betas start slowing down but I thought that wasn't until after 6000 or a heartbeat. I'm really thinking this is a bad sign. In her voicemail (can't believe I missed her call!!!) the nurse said "everything looks good for where you're at." But how can rising by only 50% in 4 days be good :(

Has anyone dealt with a wonky beta like this? I'm supposed to go back Friday but I may have them fax a blood order somewhere near home for tomorrow morning. Or should I just have faith and wait?

ETA: the ultrasound between 5w and 5w4d showed a good amount of growth. At 5w we just saw the empty gestational sac but at 5w4d we saw the yolk sac and fetal pole. I just don't understand all that growth with such a little hcg jump.
Me: 30 DH: 30 ~ TTC #1 Since August 2011 
BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
Began RE testing 8/8, Dx Unexplained, 
IUI #1 11/1=BFN Moving on to IVF 
IVF #1 12/2 ER 8R 7M 4 fertilized
12/7 Transferred 2 "perfect" little blasts 12/17 BFN
New DX= DOR, I fu*kng hate IF
1/14 Hysteroscopy, new clean uterus!
IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
 3/10 BFFN
Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
 Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

Re: Betas were doubling and now they're not

  • Honestly, I wouldn't worry at all. In fact, I asked my clinic to stop giving me beta information after a while because it was stressing me out unnecessarily. After the first few, ultrasounds are a lot more meaningful, and I really don't know why clinics keep checking betas. I'd have to go back to my notes to be sure, but I don't think they were doubling anymore by this stage. My suggestion would be to not ask for more betas and focus on the fact that your ultrasounds are doing exactly what they should be doing.

    Is your next ultrasound on Friday?
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
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  • Check out the chart here: https://www.countdowntopregnancy.com/tools/beta_doubling_calculator.phpphp
    This shows when doubling times slow down, and it's well below 6000. :)
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • That wouldn't worry me when the numbers are that high and still increasing, and you've already ruled out an ectopic, AND there's growth on an ultrasound, AND it's measuring within normal range. You are doing great!

    Seriously, I think the extra early monitoring for infertility patients is great if something does go wrong so they can tailor their approach for another try. But for the vast majority of us, it's a source of stress that doesn't particularly prevent any normal early pregnancy issues.

    If you had gotten pregnant on your own, you still wouldn't have any betas or ultrasounds for probably another month or more. I always tried to remember that when I was over analyzing early betas and growth (omfg I was sooo nervous that my baby measured 3 days behind at the first u/s). Your best signs that everything is likely fine is no bleeding and no cramps (and even with a bit of those, things are still likely fine - I had lots of cramps, and some women bleed all through a healthy pregnancy). I would try to ignore the "average" or "ideal" and just accept "normal" as "no additional need to worry" and not look further for issues that probably (hopefully) don't exist.

    Just try to hang in there - there's nothing that worrying will prevent. There's no reason to panic based on your progress thus far. Deep breaths, and try to stay distracted!
    ************************SIGGY WARNING***********************

    Me: 29      DH:  32
    Off birth control March 2012 - Actively trying Sept 2012-April 2014
    Unexplained Infertility
    BFP on May 5th after Follistim & IUI #3
    Ryan Henry - born 1/10/15, 7 lb 5 oz, 20 1/4 inches

    NTNP for a sibling starting March 2015
    Waiting on cycle to resume while EBF


    imageimage

  • Thanks ladies. I'm really trying to stay calm.
    @pblge‌ my next ultrasound is scheduled for Friday. So far away. Thanks for the chart link!

    @southernyankeegirl‌ you're right there's a lot that looks good so far. I just can't shake the feeling of waiting for the other shoe to drop so to speak.

    @xc1148 I know they wouldn't lie to me right??? I just worry that they're trying to keep me calm. But I have to believe if it didn't look good they would tell me that.
    Me: 30 DH: 30 ~ TTC #1 Since August 2011 
    BFP #1 2/28/13, Ectopic, Tubal surgery 3/25 
    Began RE testing 8/8, Dx Unexplained, 
    IUI #1 11/1=BFN Moving on to IVF 
    IVF #1 12/2 ER 8R 7M 4 fertilized
    12/7 Transferred 2 "perfect" little blasts 12/17 BFN
    New DX= DOR, I fu*kng hate IF
    1/14 Hysteroscopy, new clean uterus!
    IVF #2: bcp, Lupron, follistim 300, menopur 225. 2/21 8R 4M 3F. 3dt of 2 perfect embryos. 1 little penguin 
     3/10 BFFN
    Regrouping. Seeing reproductive immunologist Dr. Kwak Kim 6/10 
    Kwak Kim protocol: Metformin 1000mg, vitamin D 4000iu, vitamin E 400iu, baby aspirin, Metanx, levothyroxine 75mcgs 
     Surprise BFP 9/21!!! Beta #1 247, Beta #2 630. Miscarried 10/13

  • @southernyankeegirl‌ you're right there's a lot that looks good so far. I just can't shake the feeling of waiting for the other shoe to drop so to speak.
    I wish I could tell you this gets better, but it really doesn't, at least not for quite awhile.  I'm approaching 3rd trimester, and I still have moments where I feel like I'm doomed to have something tragic happen. 

    My therapist has been instrumental in helping with anxiety, and I've tried really hard to keep thinking positive.  I highly suggest seeing a therapist if you can.

    It has also helped me to remind myself that worrying won't prevent the bad things from happening, and won't really make me more prepared if something does go wrong.  All I can do is take this one step at a time, and part of that is choosing (sometimes forcefully so) to be optimistic.

    Hugs, lady!  First tri sucks for PAIF.  It does get better - at 26 weeks, I feel *almost* normal.
    ************************SIGGY WARNING***********************

    Me: 29      DH:  32
    Off birth control March 2012 - Actively trying Sept 2012-April 2014
    Unexplained Infertility
    BFP on May 5th after Follistim & IUI #3
    Ryan Henry - born 1/10/15, 7 lb 5 oz, 20 1/4 inches

    NTNP for a sibling starting March 2015
    Waiting on cycle to resume while EBF


    imageimage

  • missmarypoppins haha no they wouldn't lie to you!!! They are not in the business of keeping people calm, they are in the business of science, sometimes a little too much! You'll be fine :)
    TTC since June 2011
    DH: perfect SA
    Me: 30, moderate endo, unexplained infertility
    IUI or IVF in December



    image
  • I agree with everything @southernyankeegirl‌ has said. The growth is definitely way more important & I often have to remind myself not to worry or over analyze things.
    *******Siggy Warning*******

    *Married since 11/20/10*
    *TTC since 1/12*
    *Me - PCOS * DH - Azoo*
    *IUI clomid 5/13 - BFN*
    *IUI clomid 6/13 - BFN*
    *IUI clomid 7/13 - Cancelled due to poor response*
    *IUI follistim 9/13 - Cancelled due to over response*
    *IVF #1 - 13R, 5M, 4F, 2 transferred on day 3 - BFN & nothing to freeze*
    *IVF #2 - 7R, 4M, 4F, 2 transferred on day 3 - BFP!!!!*
    *Beta #1 15dp3dt >2,000, Beta #2 21dp3dt >17,000!*
    *U/S on 6/27/14 @ 6w4d - 2 sacs, 1 HB found @ 125bpm!*
    *First OB appt 7/24/14*

    BabyFetus Ticker
  • AMSharkAMShark member
    edited October 2014
    xc1148 said:
    missmarypoppins haha no they wouldn't lie to you!!! They are not in the business of keeping people calm, they are in the business of science, sometimes a little too much! You'll be fine :)
    I agree with this 100%.  When I got bad news from my RE during IVF#1, she didn't try to give me false hope.  The first sign was a long silence, followed by a very gentle, "This doesn't look good..."  In my experience, medical staff will not unnecessarily string you along.
    If they say, "Everything looks good..." then that's a professional opinion, based on their expertise.

    I'd tell you to relax, but I'd feel a little like a hypocrite, considering 2 out of my last 3 post on this board were about my own little freak outs.   Oh, what the heck, I'll say it anyway - Try your best to relax.  Growth on the u/s seems so much more certain than beta #s.

    *** Ticker Warning ***

    Me: 37, DH: 39, TTC 5 yrs

    2013 summary: Diagnosed with Hypothyroid; Cervical polyp removed (benign); 
    2 rounds ovidrel with timed intercourse (no result): 3 rounds IUI with clomid + ovidrel (no result)
    2014 summary (to date):
    IVF cycle 1 - ER: 4/17 (28 follicles, 3 fertilized, 2 survived to day 3);
    ET: 4/20 (3rd day, 2 embryos - 1 @ 6 cells & 1 @ 4 cells); Beta 5/1 - BFP!; 
    1st scan 5/13 - development behind, no heartbeat detected; D&C 6/2; WTF 6/13
    IVF cycle 2 - BCP begun 7/12; stims w/ HGH begun 7/26; 
    ER: 8/6, 12 follicles, 7 fertilized w/ ICSI; ET: 8/11, 3 blastocysts left, 2 transferred, 3rd arrested 8/12 - none to freeze :'(
    1st beta 8/19 - BFP! 294; 2nd beta 8/26 - 4976; 1st u/s 9/2; 2nd u/s 9/9 - two little heartbeats at 140 each!!! 
    EDD: 29-April-2015
    Other Meds: Synthroid 100 mcg/daily

      imageimageimage
    Pregnancy Ticker
  • Like so many ladies have mentioned, I think the positive growth is the most important factor now. My RE operates so differently; I only had 1 beta and as long as it was over 100 they wouldn't do any more. I had to then wait 3 weeks for U/S #1. THAT was super nerve wracking. But anyway, my point is really that although I would have liked at least 1 more beta for peace of mind, sometimes I feel like Re's do too many....

    Me: 37 | DH: 41
    TTC Since 2011 DX: Unexplained 
    IUI's #1 - 3 = BFN
    IVF August 2014: FSH 4.1, PRL 15.3, TSH 2.1, W/ AFC 8.
     08/03 ER 5R, 4M, 3F. 08/08 5DT of 1-3AA0, 2 frozen :) bfp @9dp5dt. Beta on 08/20 = 414.
    So excited to have one little bean on the way!!
     
    image 

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