Secondary IF

meds question

So my 3 cycle treatment plan is:
clomid - done
femera
gonal f

He said that my body may react differently with each med and went through the process of what each one does. They kept saying my body reacted well with clomid. I know that you don't want to do clomid for too long but wondering if it worked, worth it to try one more with that vs moving onto the next which my body may not react well to? Thoughts?

Me: 32, DH: 33
DS #1: April 2010
DS #2: July 2015 (preemie born at 31 weeks) - our little miracle conceived through ART - unexplained secondary infertility/adenomyosis

Re: meds question

  • Well this is tricky because you never know how you will respond to the others. Personally I always responded well to Clomid, so I did many cycles with just Clomid + TI we were never successful, but the stuff did what it was supposed to do for me. So the thing is, do you risk responding really crappy with Femara just to *see*? Or stick it it out with the stuff that you know works, to see if you can get a BFP? FWIW 1 cycle one Clomid is nothing, you don't want to be on it for 6 or more consecutive cycles because it builds up in your system cycle to cycle and can/will make you have a nervous breakdown after a while (Lots can attest to the Clomid crazies) 


    I would try a couple more Clomid cycles and see what happens, was there a reason they were rushing to other meds? 


    Spontaneous pregnancy #1
    DD1 July 31, 2011

    Trying for #2 since Oct 11
    732973 Clomid Cycles
    2 IUIs 
    3 Fresh IVFs= 1 Ectopic treated with MTX
    Spontaneous pregnancy #2= Ectopic #2= lost left tube
    Spontaneous pregnancy #3= DD2 January 29, 2016
    Spontaneous pregnancy #4= Ectopic #3
    Spontaneous pregnancy #5= Baby #3 is a BOY!!! 



    BabyFruit Ticker
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  • Thanks for the feedback, didn't seem like there was any particular reason which is why I questioned it. Just to see which my body responds to. Someone on a local board at the clinic said it gives them a chance to see what your body responds best to if you make the investment and move onto IVF....makes sense in that way.

    I've got an email into my nurse and see what she responds with. I guess I'll go with whatever they recommend but see if they had a good reason that I either forgot or just wasn't shared.
    Me: 32, DH: 33
    DS #1: April 2010
    DS #2: July 2015 (preemie born at 31 weeks) - our little miracle conceived through ART - unexplained secondary infertility/adenomyosis
  • pettycrockerpettycrocker member
    edited September 2014
    sailorgal said:
    Thanks for the feedback, didn't seem like there was any particular reason which is why I questioned it. Just to see which my body responds to. Someone on a local board at the clinic said it gives them a chance to see what your body responds best to if you make the investment and move onto IVF....makes sense in that way.

    I've got an email into my nurse and see what she responds with. I guess I'll go with whatever they recommend but see if they had a good reason that I either forgot or just wasn't shared.
    That's very interesting because Clomid / Femara (which are common for IUI) work in your brain, injects (most IVF cycles) work directly on your ovaries, so they wouldn't really be learning anything towards a potential IVF cycle this way. I get the concept though, my first IVF protocol sucked, so we learned a lesson there (because it sucked lol ) but if it was good, we stay on that protocol. My 3rd IVF would be the same meds as my 2nd, but I haven't gotten to it yet. 

    Good luck 


    Spontaneous pregnancy #1
    DD1 July 31, 2011

    Trying for #2 since Oct 11
    732973 Clomid Cycles
    2 IUIs 
    3 Fresh IVFs= 1 Ectopic treated with MTX
    Spontaneous pregnancy #2= Ectopic #2= lost left tube
    Spontaneous pregnancy #3= DD2 January 29, 2016
    Spontaneous pregnancy #4= Ectopic #3
    Spontaneous pregnancy #5= Baby #3 is a BOY!!! 



    BabyFruit Ticker
  • hmmmm...my RE said they like to do 3 cycles of each type of medicine to get a real feel for how your body will react.  



    imageimageimage
    image
    My FF Chart:
    http://www.fertilityfriend.com/home/490dd7
    TTC #3 since June 2013
    BFP #1 7/21/2013--EDD 3/30/14--D&C 9/24/13
    BFP #2 1/28/14--MC 2/7/14

    IUI #1 5mg Femara + trigger = BFN
    IUI #2 5mg Femara + trigger = BFN
    IUI #3 5mg Femara + trigger = BFN
    IVF #1, Stimmed for 12 days, ER 8/22/14, 9 retrieved, 7M, 7F!!  Freeze all due to fluid in uterus.
    FET end of October 2014 cancelled due to fluid in uterus due to possible c-scar defect
    Surgery scheduled 12/12/14 to fix possible isthmocele
    3/26/15 transferred one 8 cell grade 4 embryo and one 6 cell grade 3 embryo = slow rising betas for 2+ weeks = ectopic MTX shot 4/29/15
    Repeat c-scar surgery June 2015
    2nd and last IVF cycle August 2015, stimmed for 12 days, 2 egg retrieved, both mature and both fertilized.  Transferred both 8-cell embryos on Day 3, beta 9/5/15 = BFFN
    MOVING TO ADOPTION!  


  • I just got a response and they said they prefer to only use clomid once because the side effects of multi use are not desirable for most patients. Fair enough. I also read the chance of multiples is much less for femara which is a big plus to me.
    Me: 32, DH: 33
    DS #1: April 2010
    DS #2: July 2015 (preemie born at 31 weeks) - our little miracle conceived through ART - unexplained secondary infertility/adenomyosis
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