Pregnant after IF

Has anyone seen this info about betas?!

Ok, not a fan of mobile so hopefully this posts well. I stumbled across this and am feeling very nervous because I had a third beta Wednesday and I was definitely not at 35%. I guess if there's truth to this I want to prepare myself for my US.

"Morse and coworkers (2012) at University of Pennsylvania School of Medicine recommend that the beta hCG level for a successful intrauterine pregnancy should be expected to increase by at least 35% in two days. A slower rate of increase suggests a possible miscarriage or ectopic pregnancy. For women who are having a miscarriage the beta hCG should be expected to fall 36 - 47% over two days. A fall that is slower than this is suggestive of an ectopic pregnancy.

About 21% of ectopic pregnancies (pregnancies implanted outside of the uterus) have a rise in hCG similar to an intrauterine pregnancy and 8% of ectopic pregnancies have a fall in hCG similar to a miscarriage.

Serial hCG values should not be used alone to determine whether or not a pregnancy is likely to be a successful intrauterine pregnancy, a miscarriage, or an ectopic pregnancy. Serial hCG values should be used in combination with clinical judgment, evaluation of symptoms and repeat ultrasound (as needed)."


Me: 27 DH: 27

October 2013: Endo erosion/ Clear HSG

March 2014: SA #1/  2%morph, borderline sperm count, decent motility

June 2014: SA#2/  2% morph, low sperm count, worse motility

Plan: "Quick Start IVF"/antagonist protocol with Follistim, Ganirelix, Ovidrel and progesterone suppositories (yay)

High AMH (11) and Low BMI= low doses of everything to prevent OHSS

July 27, 2014: Started Follistim injections for ten days

July 31, 2014: U/S= 20 follicles, 8.5 lining, E2 is good, Ganirelix for 4 days starting 8/2

August 4, 2014: 14 follicles on-track, good lining, Trigger 8/6

August 9, 2014: 9 ICSIed/ 5 embryos; aiming for a 5dt on 8/13

August 13, 2014: 5DT of 1 4BA almost-hatching blastocyst (Please hang in, Little Bug!)

August 14, 2014: We have 3 frosties! Hope they're having fun hanging out together. :)

August 23, 2014: Beta #1: 144 8/23/14: Beta #2: 374 Beta 8/25/14  Beta #3: 6,600 9/3/14

September 9, 2014: Ultrasound #1 115 heartbeats per minute

September 23, 2014: Ultrasound #2 182 heartbeats per minute 

September 26, 2014: Love my OB's office

October 10, 2014: Our baby looks like a baby and is moving all over!  

December 8, 2014: Anatomy scan- It's a girl! 


"Hope strengthens.  Fear kills."- Karen Marie Moning

"Heaviness is only temporary; the daylight will soon break in."- needtobreathe

Re: Has anyone seen this info about betas?!

  • I know it's tempting to do all this "research" while you're in beta land, but it's so pointless. Your doctor is going to be the best guide for what is good and what is not. My second beta didn't "double" and the nurse was supremely calm. Sure enough, the third one was back on track. Every pregnancy is different! I was stressed and worried so I won't tell you not to be. But do avoid Dr. Google as much as you can :)
    TTC since June 2011
    DH: perfect SA
    Me: 30, moderate endo, unexplained infertility
    IUI or IVF in December



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  • @LO95, I'm on mobile. What were your betas?
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • edited September 2014
    The way I'm interpreting the above says that it just needs to increase by 35% in 48 hours. Therefore, if I had my beta done today, and it's 100, then 2 days later it would need to be at least 135? I see your 3rd beta, but it was done a lot later than your 2nd, so I'm not sure how you're calculating it to know it's not 35%. The % increase between your first and second beta is definitely way more than 35% if that helps, and those were done 48 hours apart.
                                         - ticker/siggy warning -

                                     ivf #1 (MFI): 18 retrieved, 16 fertilized 
         bfp: 8dp3dt, beta #1 10dp3dt: 103, beta #2 14dp3dt 637, EDD: 12.06.14! 
    Pregnancy Ticker
  • Milagros315Milagros315 member
    edited September 2014
    I'm confused. It looks like your betas are doubling every 48 hours which is perfectly normal. Nothing about your levels suggests that you have anything to worry about.

    Does that article say anything about when the betas were taken? Remember, the rate of increases decreases as the pregnancy progresses and hcg levels get higher.

    ETA: I think you are miscalculating. Your betas are increasing by well over 35%.
    ******************************************** siggy warning ******************************************

    image image

    image

    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

  • Okay, I couldn't stand the curiosity, so I pulled my laptop out just for you. ;-) Here are the calculations.

    Beta 1 - Beta 2: 34.86 hour doubling time

    Beta 1 - Beta 3: 47.84 hour doubling time

    Beta 2 - Beta 3: 52.16 hour doubling time

    You're TOTALLY fine. If your betas were only increasing at 35% every 48 hours, they would only be about 1100 right now, based on Beta #2. Keep in mind that the beta increases more slowly over time. Check out the charts here
    https://www.countdowntopregnancy.com/tools/beta_doubling_calculator.php

    This is one you DEFINITELY shouldn't be worrying about right now!
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • LOL I did the same thing @pblge! I'm sitting here with my calculator and calendar figuring out a 35% increase and then I used an online beta calculator to find out LO95's increase.
    ******************************************** siggy warning ******************************************

    image image

    image

    Married July 2011 * TTC #1 since 8/12 * Me: 29 DH: 29
    21 Cycles TI: BFNs
    DX: Stage 2 Endo, uterine polyps and paratubal cysts removed
    2/14: IVF #1 Lupron Protocol = 12R/10M/9F, no frosties; transferred one 3BB blast = BFN
    4/14: IVF #2 Antagonist Protocol = 18R/16M/15F/6 frosties; transferred one 4BB blast = BFP!!
    Beta #1 (5/12) = 232 Beta #2 (5/16) = 886 Beta #3 (5/20) = 3168
    EDD 1/18/15 It's a BOY 

    ~~~~~~ All Are Welcome ~~~~~~

  • Oh, I love you guys. I think I misunderstood how to calculate it. But you guys are veterans so now I'm feeling a little better. Thank you.

    Me: 27 DH: 27

    October 2013: Endo erosion/ Clear HSG

    March 2014: SA #1/  2%morph, borderline sperm count, decent motility

    June 2014: SA#2/  2% morph, low sperm count, worse motility

    Plan: "Quick Start IVF"/antagonist protocol with Follistim, Ganirelix, Ovidrel and progesterone suppositories (yay)

    High AMH (11) and Low BMI= low doses of everything to prevent OHSS

    July 27, 2014: Started Follistim injections for ten days

    July 31, 2014: U/S= 20 follicles, 8.5 lining, E2 is good, Ganirelix for 4 days starting 8/2

    August 4, 2014: 14 follicles on-track, good lining, Trigger 8/6

    August 9, 2014: 9 ICSIed/ 5 embryos; aiming for a 5dt on 8/13

    August 13, 2014: 5DT of 1 4BA almost-hatching blastocyst (Please hang in, Little Bug!)

    August 14, 2014: We have 3 frosties! Hope they're having fun hanging out together. :)

    August 23, 2014: Beta #1: 144 8/23/14: Beta #2: 374 Beta 8/25/14  Beta #3: 6,600 9/3/14

    September 9, 2014: Ultrasound #1 115 heartbeats per minute

    September 23, 2014: Ultrasound #2 182 heartbeats per minute 

    September 26, 2014: Love my OB's office

    October 10, 2014: Our baby looks like a baby and is moving all over!  

    December 8, 2014: Anatomy scan- It's a girl! 


    "Hope strengthens.  Fear kills."- Karen Marie Moning

    "Heaviness is only temporary; the daylight will soon break in."- needtobreathe

  • You can call me the Official Arbiter of Worry. ;-)
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
    http://i955.photobucket.com/albums/ae39/catfreeburg/866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimageimageimageimage
    image
  • Step away from Google and stop comparing your betas to everyone else's.  Easier said than done...but you're fine!


    Me 33, DH 37 -- TTC since Jan'12 -- Low AMH (0.78) & endo, SA w/ low motility
    IUI's 1-3 = BFN, IVF converted to IUI 4/13 = BFN
    IVF 1.2: 8R 6M 4F -- 2 blastocysts frozen, FET 8/15 = BFP!!
    Beta #s = 445;1,098; 9,545  -- EDD 5/2 -- Team Pink!
    Camila Josephine arrived 4/30 :)
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