Trouble TTC

Follie Size Question

I decided to curtail my consultation with Dr. Google and just go for the truth.

Nurse said it's pretty unlikely that my 15mm follie will keep maturing since I have a 19.5 dominant follie. She said a 4+mm difference makes it hard for the smaller one to catch up. 

I am very curious if you've heard similar info on Letrozole/Femara or anything else. For some reason it's gotten into my head that I have to know if we have any chance of fraternal twins this cycle. :)

Sorry for being impatient and ridiculous! Thank you....
January 3T Siggy Challenge - New Year's Resolutions
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Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
IUI #5.1 - Jan (Bravelle) Cancelled 
Planning to start IVF in March!
***All Welcome***

Re: Follie Size Question

  • I've never had more than one follicle, so I'm not sure, but I'm pretty sure I heard anything around 15 or over has the potential to be mature. It might depend on your E2 also?? I know that's only partially helpful at best.... I think at my last cycle I triggered with one 16 mm follicle though, so that should give you some idea.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • Are you triggering now or waiting?
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


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  • If you're using a trigger shot it should force your body to ovulate any mature eggs (where your body would normally only release one). My doctor told me anything over 15mm is considered large enough to have a mature egg. I don't know anything about letrozole or femara... but I would guess even if your 15 doesn't get any bigger, that yes, there's at least a small possibility of twins! Oh and I agree with lebradford that your E2 levels factor in and can give a clue about whether both are mature.
    **************
    Married in 2011, NTNP until early 2012, TTC since early 2012

    My husband was diagnosed with state IV colon cancer in 2009. Surgery and six rounds of chemo left him in remission (yay!) but with low testosterone. He took Androgel for two years starting in Jan 2011.
    -SA in Jan 2013: big fat zero; stopped Androgel
    -varicocelectomy in June 2013
    -SA in Dec 2013: 23mil/ml, really low morph
    -SA in March 2014: Count doubled! Morphology apparently no longer an issue.

    Treatments:
    April 2014: hysteroscopy
    June 2014: TI (clomid/bravelle/ovidrel: 2 folliclces) = BFN
    July 2014: IUI#1 (clomid/bravelle/ovidrel; 1 follicle, 23mil post-wash) = BFN
    August 2014: IUI#2 (clomid/bravelle/ovidrel; 1 follicle, 43mil post-wash) = BFN
    September 2014: IUI#3 (clomid/bravelle/ovidrel; 2 follicles, 15mil post-wash) = BFN
    October 2014: IUI#4 (clomid/bravelle/ovidrel; 1-2 follicles, 12mil post-wash) = BFN
    November 2014: IUI#5 (clomid/bravelle/ovidrel: 1 follicle, 23mil post-wash) = BFN
    December 2014: IUI#6 (gonal-f/ovidrel): 2 follicles, 55mil post-wash) = ???

    *all are welcome!*

  • I think there's just a small possibility. My RE considered 18 to mature (enough to trigger), and it could grow a little between the time you trigger and you ovulate.

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

    image    image
  • ky29ky29 member
    I would think if you have a 15 at the time of trigger, there's a good chance that it will be mature by the time of the IUI.  Today my nurse told me that even 14s at trigger can contain a mature egg. 

    image
    TTC since March 2012
    DX: MFI (4% motility)

    Cycle 13: Natural cycle w/ HSG test = BFP
    Identical twins! 
    Lost my angel boys at 10.5 weeks

    Cycle 14-16: Natural Cycles = BFN
    Cycle 17: Follistim + Trigger + IUI = BFN
    Cycle 18: Natural Cycle = BFN
    Cycle 19: Follistim + Trigger +IUI#2
    Polyp found: SIS 11/11 - hysteroscopy 11/14
    Cycle 20: Follistim + IUI#2 = BFFN
    Cycle 21: Follistim (adj. dosage) + IUI#3 TI  = BFN
    IUI cancelled due to weather
    Cycle 22: Follistim + IUI#3.1 = BFN

    Cycle 23: treatment break, IVF consult
    Cycle 24 - 26: natural cycle w/ acupuncture + Chinese herbs = BFN
    Cycle 27: Follistim + IUI#4 = BFFN
    Natural Cycles until IVF
    Cycle 30: IVF#1 - Starting with Menopur + Follistim + Ganirelix
    17 retrieved, 12 fertilized, 5dt w/ 2 blasts, 5 frosties

    Betas:  #1-156(9dp5dt), #2-1200(13dp5) #3-6112(17dp5)
    Ultrasound #1 10/6: 1 bean!
    TEAM BLUE!

    My Chart
    ~~ALL WELCOME~~

    BabyFruit Ticker
  • @lebradford Sorry I should have clarified, I am not using a trigger shot (I feel comfortable with OPKs).

    Thanks for the feedback everyone!! I guess I will just assume there is only a tiny chance of twins. :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • My re says not to count out the 1.5s. Twins are a small possibility - then again, I had many cycles with two follies at or over 1.5 and got bfns

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

  • I'm going to trigger today and the nurse says I have 2, one is 21mm and the other is 16mm. They are counting the 16mm as a mature egg. I think it is very possible yours can mature in time for ovulation. I did femara + injects though so I don't know if the follicle size changes anything.

    Good luck BunnyBerry!!!!!! 
    *** If you want to know where I (and soo many others) have gone, click here ***
  • @emmuffy @sweetieshellieh Oh dear, I guess you two heard the opposite! Although, I think injects cycles have mature eggs in smaller follies because they mature faster as the follicles are growing.

    No expectations here - after 50+ BFNs, can't say we're expecting to get pregnant in any given cycle. But it kind of felt cool to think we might be in the running for twins, as I've never had multiple follies before. :) Okay, back to real life!!
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Sorry @bunnyberry I wasn't meaning to suggest you shouldn't be optimistic. It's always good to be optimistic. I have my hopes up for you this cycle!! FX!!!!

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

  • @emmuffy No need to be sorry, I know you were being honest, not negative! :) Lol I tend to avoid optimism regarding TTC because it comes with big disappointments...was actually kind of looking for some "you can stop imagining you might have twins now so stop getting your panties in a knot" kind of replies.  :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Lol panties in a knot lol love that comment @BunnyBerry !
    *** If you want to know where I (and soo many others) have gone, click here ***
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