WTF #3 (Loss Mentioned)

Carol77B · July 2014

Hi Ladies,

I'm back. I had my WTF for IVF #3 (which resulted in an early pregnancy loss) yesterday. My RE did take my concerns about DH's sperm quality seriously (he had a partially successful vasectomy reversal and we seem to have fertilization problems and problems with the embryos growing past day three) and wants DH to see the urologist they work with and to start taking supplements (ConceptionXR). He thought it might be possible that if we could increase his count (which is averaging 4 mil to at least 8 mil) that we could try IUIs. I'm not as interested in that, but I am really interested in improving the quality/quantity we have to work with for IVF.

I also asked about adding HGH to the mix and he is going to look into it and discuss adding it to my protocol with some of the other REs in the practice. He said that when they were part of a study a few years back using it, that the test group was so small it wasn't possible to really make a determination about the effect. He also cautioned that it was really expensive (but nothing about this is cheap, since we are 100% OOP). We also discussed waiting until day 5 instead of day 3 for transfer (risking having nothing to transfer) but he didn't think that would be a good idea since he did think that the embryos would have a better chance if we transferred them early, even if they aren't "perfect." The current plan will be to still use the implantation meds (Lovenox, baby Aspirin, Prednisolone) and the antagonist protocol. I'm going to wait to hear back about if we are going to add HGH or make other tweaks to what we did last time (estrogen priming protocol). We briefly discussed the Micro-dose Lupron Protocol (which was a disaster for me and he didn't think it was worth trying again) and the (full?) Lupron, but he thought it could be risky. I forgot to ask if I should expect to do another endometrial biopsy.

I'm waiting on AF (my D&C was on 7/16) and since we are going to have my DH re-evaluted by a new urologist and start supplements, I don't expect that we will be moving forward with IVF #4 until at least November. The embryo center closes for two weeks in December, so if we don't make November, I expect we'll be in Jan. So I'm working on weight loss and getting to the gym in the meantime. I'm also continuing to take the COQ10, DHEA, and Folgard and will start back with the acupuncture.

I did find my RE's thoughts on batching and mandatory 5-day transfers interesting. He said that by the way that success rates are currently calculated, the centers that do those don't have to count the IVFs that don't lead to transfers in their numbers so that he says they have artificially high success rates. However, he said that they are changing the way the SART data is reported and all centers will need to report on all IVF cycles, including those that don't lead to transfers so he thinks those centers are going to see big drops in their success rates, as much as from 70% (currently) down to 30%.

ronniesgirl1981 · July 2014

I am so sorry to see you back here.

Jetta83306 · July 2014

So sorry for your loss

((HUGS))

emmuffy · July 2014

So sorry for your loss. Good luck for your plan moving forward.

Justone13 · July 2014

You know I'm sending hugs!! >:D<

StacyLH24 · July 2014

I'm so sorry for your loss. I'm glad that your RE was willing to listen to your ideas.

pblge · July 2014

((Hugs)) Hope that the sperm issues can be resolved and give you better results. Hope this time off will be good for you. Sending you positive thoughts. Thanks for sharing the SART stuff...interesting.

AMShark · July 2014

I'm so sorry to hear about your loss. (( hugs ))

I just started on HGH last night for my second IVF cycle. If you have questions about it, I can let you know my personal experience. (Or, at least, I should be able to after my retrieval).

FYI - It took between 7-8 weeks for AF to come after my D&C at the beginning of May. I was told the average is about 6 weeks. I didn't know it at the time - I thought AF would come shortly after the D&C. Just wanted to make sure you don't get as worried as I was.

gnl42 · July 2014

I'm so sorry for your loss. I really hope the next step will bring you good news.

Lesliem0901 · July 2014

I'm so sorry for your loss. Big hugs...

Carol77B · July 2014

@AMShark, thanks for letting me know about AF. I've been Googling averages on how long it takes to return, since I think my paperwork said up to six weeks. And I'm very eager to hear about your experience with using the HGH. I hope you see great results!

fjamil1 · July 2014

So Sorry for your Loss ((Hugs)).

gsancho · August 2014

I'm so sorry for your loss...there really are no words. But hopefully the HGH and urologist help out.

Sigh202 · August 2014

So sorry you're back. It sucks to be back to square 1 when you think you've finally succeeded.

mrscsw · August 2014

I'm so sorry.

scooteriste · August 2014

I'm not sure how I missed this when you posted it. I am so sorry for your loss and sorry to see you back here. (((Hugs)))

There are a lot of similarities in our cases so I always find your REs insight very interesting. Thank you for sharing it here. I switched to an RE that doesn't require Day 5 transfers in order to give our embryos a better shot. We have the same issue with them falling apart after day 3. It's such a frustrating problem to have because there is no scientific reason why that happens. It can be chromosome abnormalities, male factor or "other". All we can do is pull out all the stops and hope for the best.

Sunny B · August 2014

I'm so sorry. That's really interesting info that your RE shared. I wish you so much luck going forward.

WTF #3 (Loss Mentioned)

Re: WTF #3 (Loss Mentioned)

Me 33, DH 37 -- TTC since Jan'12 -- Low AMH (0.78) & endo, SA w/ low motility
IUI's 1-3 = BFN, IVF converted to IUI 4/13 = BFN
IVF 1.2: 8R 6M 4F -- 2 blastocysts frozen, FET 8/15 = BFP!!
Beta #s = 445;1,098; 9,545 -- EDD 5/2 -- Team Pink!

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WTF #3 (Loss Mentioned)

Re: WTF #3 (Loss Mentioned)

Me 33, DH 37 -- TTC since Jan'12 -- Low AMH (0.78) & endo, SA w/ low motilityIUI's 1-3 = BFN, IVF converted to IUI 4/13 = BFNIVF 1.2: 8R 6M 4F -- 2 blastocysts frozen, FET 8/15 = BFP!!Beta #s = 445;1,098; 9,545 -- EDD 5/2 -- Team Pink!

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Me 33, DH 37 -- TTC since Jan'12 -- Low AMH (0.78) & endo, SA w/ low motility
IUI's 1-3 = BFN, IVF converted to IUI 4/13 = BFN
IVF 1.2: 8R 6M 4F -- 2 blastocysts frozen, FET 8/15 = BFP!!
Beta #s = 445;1,098; 9,545 -- EDD 5/2 -- Team Pink!