Infertility

What time of day did you take lupron for IVF?

Hi Today I start lupron for my upcoming IVF cycle. Today is cycle day 21 for me. The nurse called this morning and left a message that I was to start the lupron, but she didnt say when to take it. Of course by the time I called back they were gone for the day. So I took it at 5:30pm. I am just wondering when you were told to take it if you were told a specific time at all? Thanks
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Re: What time of day did you take lupron for IVF?

  • I always took mine at night (I can't remember if they told me to take it at night, I don't think so though). I think it's more important to take it at the same time every day

    TTC since April 2012

    BFP #1, 10/03/2012 - EDD 6/15/2013 - MMC 11/15/2012 - D&C 01/04/2013

    BFP #2, 04/06/2013 - EDD 12/17/2013 - MC 04/19/2013

    6/12/2013 Diagnosed with Balanced Translocation (12 & 16)

    IVF #1 with PGS: 10/2013: Canceled 9/27/2013 for issues with genetic lab

    IVF #1.5 with PGS: 11/16/2013: Canceled. 11 eggs retrieved, 9 mature & 9 fertilized, all unhealthy embryos

    IVF #2: 1/22/14: Canceled. 16 eggs retrieved, 14 mature, 7 fertilized, all unhealthy embryos

    IVF #3 with PGS: 5/10/2014: Switched to FET in July. 10 eggs retrieved, 9 mature, 8 fertilized, 2 healthy embryos!

    FET #1: 7/31/2014: Transferred 2 nearly perfect (6AA, 6BA) healthy embryos- BFFN

    Laproscopy: 10/2014: Healthy uterus

    IVF #4: 12/8/2014: Canceled. 17 eggs retrieved, 15 mature, 10 fertilized, all unhealthy embryos



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  • I'm instructed to take mine between 6-8 am every day

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

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  • CMH25CMH25 member
    I was just told to be consistent with the time of day that I choose. GL!
  • jencity9 said:
    I'm instructed to take mine between 6-8 am every day


    Exactly this for me.



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

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  • ash_16ash_16 member
    I just started my lupron and I take it at 6pm every day. They didn't say an exact time, just to take it at night
    ~~*~~ TTC our first little bundle of joy! ~~*~~ Me (25) DH (27) TTC #1 since March 2012 Trying to Conceive Ticker Daisypath Anniversary tickers
  • CMH25 said:
    I was just told to be consistent with the time of day that I choose. GL!
    This. 
    Me: 34 / DH: 33
    19-year history of endometriosis. Multiple surgeries and cyst removals. Forced directly into IVF due to blocked tubes and severe adhesions.
    IVF w/ICSI and CCS #1 - Dec 2013 - Only 1 normal. Ended in CP
    IVF w/ICSI and CCS #2, at CCRM - March 2014!
    14R, 12 ICSI'd, 11F, 6 for CCS, 5 healthy blasts frozen!
    Two 5BB blasts transferred 9/10; First beta 9/19: 109; second beta 9/22: 550!
    EDD: 5/29/15

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  • I have a question. Does everyone keep it in the fridge or on the counter? When I google I get mixed reviews. The box says 68-77 degrees but I see where so many are putting it in their fridge. So I'm confused. I just started taking it last night and I just keep it in it's box so far.
    Fucking bump!!!!
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  • I think it depends if you have lupron or leuprolide Acetate ( the generic version). The leuprolide acetate does not need to be refrigerated at all
    Lilypie Pregnancy tickers
  • I think it depends if you have lupron or leuprolide Acetate ( the generic version). The leuprolide acetate does not need to be refrigerated at all

    That's what I have. They really need to be VERY clear on the box. This is stressful enough to not question if I need to keep cold or not.

    @GrailSeeker14‌ during stims I keep my Gonal/follistim in the refrigerator the whole time. My house stays between 72-75, I live in the Deep South and it's hot so we love our air conditioner. I've heard some people warm it up but I never did and it didn't hurt.
    Fucking bump!!!!
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  • jlb902jlb902 member
    I was told between 5-9 pm and to try to take it in the same hour every night.

    *** BFPs and Loss Mentioned ***


    TTC since 08/2012

    BFP 12/28/12-- EDD 9/19/13-- M/C (d&c) on 1/31/13

    7/15/14 -- IVF #1

    ER on 7/26/14 -- 15 R, 8F

    ET on 7/31/14 -- 1 transferred (4aa); 4 frosties!!!

    BFP 8/5/14-- EDD 4/18/15

    Beta #1 (14dpo):  223, Beta #2 (17dpo): 898

    First u/s -- 8/28/14= 1 beautiful baby with a hb of 131

    10/25/14- It's a GIRL!

    11/24/14- DX with Complete Placenta Previa (Stage IV)

    1/12/15- Placenta Previa has moved to Marginal!! (Stage II)

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  • Sha259Sha259 member
    I take mine in the AM (usually around 7am), while I stim in the PM (usually around 8-9pm).

    As for temperature, I have the Leuprolide Acetate and keep it at RT. If the box says to keep below 77degrees, and you experience a day of really hot temps, I would probably put them in the fridge. For these types of drugs, colder is typically better if given the choice of either cold or hot. Heat degrades and denatures, so if we want our full dosage strength we've got to keep our meds active!! :)

    I specifically keep all my meds (even the non temp sensitive ones) in a closet in my house that I know stays really cool, and we have A/C. But if our A/C broke or we lost power, I would quickly put the temp sensitive stuff in the fridge to make sure that it never got too hot.
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