Trouble TTC

Severe Anxiety from Progesterone Suppository Withdrawal Anyone? - kinda long break down mode

Hello:

I stopped my progesterone suppositories yesterday after my BFN and have been having pretty severe anxiety. Has anyone else experienced this, if so when did it subside? 

I'm ALREADY super anxious and today I had a total breakdown that started at 4 in the morning! I woke up completely awake at 4 and started worrying about my home loan (I'm currently in escrow) and inspection report (lots of electrical and wiring issues). I sat there fore three hours going over my loan documents, reviewing word for word the inspection report and researching how much it will cost to repair all the issues until I could call my DH (he was visiting family this week) and flipped out about how I wanted to cancel the loan, it was too much stress, to expensive to fix everything blah blah blah. I started crying and felt very panicky. Then I sat there and watched the minutes go by until 8 so I could call my lender with my loan questions. FINALLY I got a hold of her and it slightly relieved my anxiety. 

I took some anti-histamine because, on a separate issue, I have a horrible rash on my face from lemon juice (I guess I'm slightly allergic to lemons?) so I've been taking anti-histamines to help the rash in hopes that it goes away by tomorrow (thank god I was able to work from home today, but I'll have to venture out tomorrow with my BIG RED face ugggg) and it calmed me down a bit, but didn't knock me out (damnit I really need a nap!). So anyway, I feel very manic right now and did some dr.googling and found progesterone withdrawal could cause anxiety, but the research was mostly based on people taking hormone replacement, not from suppositories. 

AHHHHH I hate LEMONS and PROGESTERONE. For anyone who read this thanks for listening to my anxiety ridden post :)

Me: 33, DH: 32

TTC: 2 years
Fertility blood tests all normal
Tilted uterus
3 day ultrasound 17 follicles
HSG: 11/13/13- tubes open
DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
All infection disease and immunity blood tests NORMAL

FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

3rd cycle benched due to cysts - TI with OPK tests -  BFN

3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

JANUARY SIGGY CHALLENGE...This is so me!

image


Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

image

Never thought I would like long hair....

image

Re: Severe Anxiety from Progesterone Suppository Withdrawal Anyone? - kinda long break down mode

  • kristyn831kristyn831 member
    edited July 2014
    I'm sorry you're struggling with anxiety. I get it too and it's a terrible feeling and then people expect you to just relax, as if it's that easy. I have not experience with progesterone withdrawal but I do get severe anxiety towards the end of my 2WW when I'm guessing my progesterone levels drop. Have you tried exercising or acupuncture? I would talk to your doctor, maybe they are comfortable giving you something to take the edge off if you can't overcome it on your own.


    image




    Me: 33, DH: 35
    Married 10/13, TTC since 7/13
    Dx: MFI
    IUI #1 7/14: BFN
    IUI #2 8/14: BFN
    IVF #1 11/14: 20R17M15F
    Transferred 1 three day embryo! 7 frosties!
    BFP!  EDD 7/27/15



                                                                      image

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  • Tiko99Tiko99 member
    I'm sorry you're struggling with anxiety. I get it too and it's a terrible feeling and then people expect you to just relax, as if it's that easy. I have not experience with progesterone withdrawal but I do get severe anxiety towards the end of my 2WW when I'm guessing my progesterone levels drop. Have you tried exercising or acupuncture? I would talk to your doctor, maybe they are comfortable giving you something to take the edge off if you can't overcome it on your own.
    Thanks kristyn831. I take xanax xr nightly in general for anxiety, but was afraid to take one last night with my antihistamine so I don't think it helped I missed my dose. Damn lemons! I started going in for acupuncture last cycle and will continue through this cycle, which does help. I love me some acupuncture :)

    Me: 33, DH: 32

    TTC: 2 years
    Fertility blood tests all normal
    Tilted uterus
    3 day ultrasound 17 follicles
    HSG: 11/13/13- tubes open
    DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
    All infection disease and immunity blood tests NORMAL

    FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

    IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

    3rd cycle benched due to cysts - TI with OPK tests -  BFN

    3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

    Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

    JANUARY SIGGY CHALLENGE...This is so me!

    image


    Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

    image

    Never thought I would like long hair....

    image

  • I had really bad panic attacks right around the time I finished my Provera. I had never had one before and I had no idea what was happening to me.
    Anniversary

  • I'm so sorry! Anxiety sucks, and it's really unfair that there's the double whammy of emotional and physical triggers. And so, so sorry you have to go in to work with lemon allergies. :( 

    MH tends to be quite anxious, and it can be frustrating when he "shares the love" with me, because I am not a worrier! But I know that he does his best to work through his worries, and sometimes he needs to voice them and get some reassurance in order to move through it. I want to thank you for sharing your experience, because sometimes I forget how hard it can be for him and I get mad that he's making drama or trying to stress me out. But I need to remember how hard it is on him, and thank God that we can support each other. :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Ugh that sounds horrible. I hope you feel better physically and mentally soon!

    Missed M/C natural cycle 10/2013

    DX PCOS 3/2014

    2 cycles Clomid 50 mg + Ovidrel + TI

    1 cycle Clomid 50 mg + TI - no response stair-stepped to Clomid 75 mg + Ovidrel + TI

    1 cycle Clomid 50 mg + Ovidrel + IUI

    1 cycle Letrozole 7.5 mg + 150 mg Follistim + Ovidrel + TI

    1 cycle Letrozole 7.5 mg + 150 mg Folistim + Ovidrel + IUI

    1 cycle Letrozole 7.5 mg + 150 mg Follistim  - no response, repeated Letrozole 7.5 mg + 150 mg Follistim + Ovidrel + IUI = success! 12/2014

    Beta 1 - 15 dpiui, 324, Beta 2 - 17 dpiui 750. Twins!!

    My Blog: pcosandpizza.blogspot.com


  • Anxiety sucks. I'm sorry you're dealing with it. You have so much going on (with your body and in your life) that I think the increased anxiety is appropriate (though still unpleasant). I hope you start feeling better once your hormones level out and your rash clears up.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • Tiko99Tiko99 member
    Thank everyone for your responses. I feel so much better and truly believe it was the huge dip in progesterone that caused my anxiety. 

    Me: 33, DH: 32

    TTC: 2 years
    Fertility blood tests all normal
    Tilted uterus
    3 day ultrasound 17 follicles
    HSG: 11/13/13- tubes open
    DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
    All infection disease and immunity blood tests NORMAL

    FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

    IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

    3rd cycle benched due to cysts - TI with OPK tests -  BFN

    3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

    Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

    JANUARY SIGGY CHALLENGE...This is so me!

    image


    Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

    image

    Never thought I would like long hair....

    image

  • I'm sorry your having anxiety and I hope you find a way to relieve it, it must be terrible!!!! I've only noticed that the first 2-3 days I started my Prometrium I was a raging bitch! I've leveled off now. Hugs to you, feel better soon!!
    Married 07/15/2006 DS # 1&2 born 07/06/2007 TTC# 3 since 10/2013
  • I have panic disorder and have gotten a pretty good handle on it now. I still have a RX for Xanax. I am supposed to start progesterone next month after clomid and now I'm nervous it will cause an attack...at least I know ahead of time now. Yikes.... I feel your pain
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