Trouble TTC

shortest/longest medicated cycle?

I recently experienced vastly different cycle lengths: 4 weeks to ovulation in for cycle 1, ~10 days to ovulation for cycle 2. My RE's explanation was that PCOS makes cycle irregular. While this much disparity is not necessarily common, it is possible. So glad to be special again.

I'm curious about your experience. How long were your longest and shortest medicated cycles?


***siggy warning***

Me: 29; DH: 53
TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

Moving on to IVF. (Why we're moving on to IVF)

IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

 image 
 image    image

Re: shortest/longest medicated cycle?

  • Were those cycles medicated? If not that is unfortunately common for PCOS. Cycle length can vary even when you're medicated depending on how you respond.
    TTC #2 since 2011 (took 1.5 years to conceive spontaneously after multiple failed clomid cycles and 1 failed clomid +IUI)
    Me- PCOS, borderline hypothyroid
    Him- low concentration/count

    Feb 2014- started acupuncture
    Feb 2014- BFP
    March 2014- m/c @ 5 weeks
    May 2014- HSG, all clear, started Synthroid, Femara 5mg CD 3-7 + trigger + TI= BFN
    Waiting for new RE appointment end of July 2014

  • Loading the player...
  • @Mrs.Ess: Yes, both were medicated. They both began with Letrozole for 5 days. They couldn't get anything to grow even after a few days of shots on cycle 1. Cycle 2 I ovulated spontaneously before they even started monitoring.


    ***siggy warning***

    Me: 29; DH: 53
    TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

    TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
    IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
    IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
    IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

    Moving on to IVF. (Why we're moving on to IVF)

    IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
    FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

     image 
     image    image
  • Interesting. What dosages were you on and what were the "shots"?
    TTC #2 since 2011 (took 1.5 years to conceive spontaneously after multiple failed clomid cycles and 1 failed clomid +IUI)
    Me- PCOS, borderline hypothyroid
    Him- low concentration/count

    Feb 2014- started acupuncture
    Feb 2014- BFP
    March 2014- m/c @ 5 weeks
    May 2014- HSG, all clear, started Synthroid, Femara 5mg CD 3-7 + trigger + TI= BFN
    Waiting for new RE appointment end of July 2014

  • @Mrs.Ess: Letrozole 2.5 mg both times. Bravelle 75 IU per night, again both times.


    ***siggy warning***

    Me: 29; DH: 53
    TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

    TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
    IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
    IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
    IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

    Moving on to IVF. (Why we're moving on to IVF)

    IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
    FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

     image 
     image    image
  • Sorry I don't know much about bravelle. I know medicated cycles can vary but it does seem like you've been all over the place. I hope they can figure out the right plan for you soon!
    TTC #2 since 2011 (took 1.5 years to conceive spontaneously after multiple failed clomid cycles and 1 failed clomid +IUI)
    Me- PCOS, borderline hypothyroid
    Him- low concentration/count

    Feb 2014- started acupuncture
    Feb 2014- BFP
    March 2014- m/c @ 5 weeks
    May 2014- HSG, all clear, started Synthroid, Femara 5mg CD 3-7 + trigger + TI= BFN
    Waiting for new RE appointment end of July 2014

  • Both of my medicated cycles so far have just been with Clomid. My first one I ovulated on CD 26 and the second one I ovulated on CD 21. I think it's pretty common for your medicated cycles to potentially get short as time goes on because they figure out what dosage to start you on and it gets more efficient. I think yours is an extreme example though.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • ***c/p mentioned***


    @rainbowbridge14: Nope, no BCP. Just one cycle into another, though I had a c/p the first cycle. AF started the day I had the second beta test, so I think it was combo AF-c/p bleeding. By the time beta dropped below 5 (~cd5), I already had a follicle around 11.7mm.

    @lebradford: That's the impression the RE gave me. So glad to be special! (<--sarcasm, just in case that wasn't clear)


    ***siggy warning***

    Me: 29; DH: 53
    TTC since February 2013 --- mild thin PCOS (or not, depending on which RE you ask), MFI

    TI#1: BFN (April 2014; Clomid 50mg x5 days, Estrace x5 days, Clomid 50 mg x4 days)
    IUI#1: c/p (May 2014; Letrozole 2.5 mg x5 days, Estrace x5 days, Bravelle 75 IU x10 days)
    IUI#2: abandoned... O'd early & DH hormone issues (June 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x2 days)
    IUI#2.1: BFN (July 2014; Letrozole 2.5 mg x5 days, Bravelle 75 IU x4 days)

    Moving on to IVF. (Why we're moving on to IVF)

    IVF#1 (w/ICSI): BCP 9/9-9/23. Gonal-F, Ganirelix, Low-dose HCG (antagonist protocol). 41R/35M/32F... 2 transferred on 10/14, 14 frosties! On cabergoline to help avoid OHSS. BFN, possibly because of 90% drop in estrogen and progesterone a few days after ET.
    FET#1: Transferring 2 on January 8. BFP! beta#1 (1/17): 408, beta#2 (1/20): 1310, first u/s scheduled 2/5

     image 
     image    image
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