Trouble TTC

Finally, I'm going to see an RE and some other junk...

Good News:  As the title says, I'm going to see an RE at the University hospital tomorrow afternoon!  Yay!  I'm a bit nervous and not sure what they are going to do.  Anything I need to know?  My husband is going too, I'm so glad he gets to go, we weren't sure if he would be able to with work being short, but they are not going to be short tomorrow (well now they will be with him gone...)

Bad News:  I never got a + on my OPKs so I think we missed our chance for IUI#2, but considering I supposedly have PCOS (see other junk note below) I guess they don't work.  Can anyone actually tell me WHY they don't work with women with PCOS?  I can't seem to find a "real" answer anywhere... This ticks me off because by now we should have had 4... Oh well, on the bright side I finally get to see a specialist and someone who deals with this on a daily basis. Hopefully things are looking up!

Other Junk:  I am a little upset with my OB's office.  I got all my records from them and the notes from when I had an u/s to check for PCOS the results say "POSS PCOS" and hand written on the bottom of the same page is "?PCOS"  WTH does that mean! A year and a half and I'm just now finding out this is a POSSIBLE dx!  Grrr!

Back to the RE appointment, since it seems like OPKs are unreliable for me, would it be prudent to ask for a trigger for next month??  I'm also going to ask for something other than clomid, because that's all I've been on so far...  Any other suggestions for my first appointment?  Ahhh!  I'm super excited!!

 

Brief history since I am a little technologically challanged and can't figure out how to SAVE a siggy!  :-)

TTC since Nov 2011

Me: Possible PCOS 2/2013

DH: SA 4/2013-abnormal (low count [17.6 million/ml] and motility [0%, swear that is what the paperwork says]), 2nd SA 11/2013-Normal (37.1 million/ml & 60%)

Jul 2013-50mg Clomid, TI, BFN, Day 21 Progesterone-21.30 ng/ml, according to my chart I got a surge, but got + 2 days in a row...

Jan 2014-50mg Clomid, TI, BFN, Day 21 Progesterone-28.48 ng/ml, told I didn't need to keep testing, no LH surge??

Feb 2014-50mg Clomid, TI, BFN, also had TSH tested-high for TTC (3.16), Rx for Levothyroxine 25mg, possible LH surge

Mar 2014-50mg Clomid, supposed to be IUI#1.1, no LH surge, TI as best we could, BFN, HSG performed-everything ok

Apr 2013-50mg Clomid, supposed to be IUI#1.2, out of town on mini vacay/DID get a surge, TI, BFN

May 2013-50mg Clomid, IUI#1.3, got LH surge, had IUI, BFN

Jun 2013-50mg Clomid, IUI#2, no LH surge, Retest TSH-very good (1.77)

Going to see RE on June 30th

Me: PCOS Dx: Feb 2013 and Low Thyroid Dx: Feb 2014

DH: SA #1: Apr 2013 – low count/low motility, SA #2: Nov 2013 - Perfect

*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~*~

TTC History

Off BC November 2011

Visit with OB/GYN February 2013

Ultrasound confirms PCOS, OB/GYN suggests Clomid

Due to a bad beginning in 2013 didn't start Clomid right away

Clomid +TI August 2013 – BFN

Another break, 2013 was a really bad year for us...

Clomid +TI January 2014 – BFN

Clomid + TI February 2014 – BFN

Follow up with OB/GYN, tests Thyroid – LOW

HSG planned for March 2014

Clomid +IUI #1 planned also for March 2014

Re: Finally, I'm going to see an RE and some other junk...

  • The RE will probably want to do even more tests with you before they start a cycle (an HSG, a saline u/s, more bloodwork).    Then they will figure out a plan.  My RE said that Clomid doesn't work as well for ladied with PCOS because it thins out the uterine lining so she put me on the Letrozole with an Ovidrel trigger shot and I've had a much better response with that.  And I have no idea why the stupid OPKs don't work with people with PCOS but I know for me they don't so I've just stopped using them completely.

    Me: 30 yrs (PCOS), DH: 28 yrs (SA normal)
    June 19, 2008: Started dating
    August 12, 2012: Got married
    September 2012: Came off BC pills after 12 yrs
    September 2012-May 2013: Irregular periods (every 45-55 days), no positives on OPKs, used fertility friend
    May 2013: Started actively TTC, talked to OB about irregular periods and possible anovulation
    October 2013: HSG all clear, hormone levels normal, U/S showed polycystic ovaries, PCOS diagnosis
    February 2014: Clomid 50mg days 4-8, many follicles on CD14 but none bigger than 8mm
    March 2014: Switched to RE, saline u/s all clear
    April 2014: 3hr glucose showed IR, started on Metformin 1000mg/day, put on low-carb low-sugar diet
    June 2014: Femara 2.5mg x10 on CD3, 19mm follicle on CD17, Ovidrel, TI, Endometrin suppositories = BFP!!!

    Our little one due March 11, 2015

  • catlover790catlover790 member
    edited June 2014
    Hi and good luck at your appointment. At my first appointment the RE talked with us about our history, and I'm sure they will go over the paperwork that you have from your OB but they will probably want to do their own blood tests as well. I also got a transvaginal ultrasound (so be prepared for that). It was more of an introduction. They may have your DH do a SA if it's a good time for him. we were able to drop my DHs sample off from home on another day. I hope it goes well!

    I have read the reason OPKs don't work for PCOS ladies as well is because PCOS women tend to have higher LH levels at all times which causes multiple days of positive OPKs or false positives. I don't remember if this is right so please correct me if I'm wrong!

    autocorrect changed transvaginal to translational!
    ***********siggy warning **********



    Me: 26 DH: 27
    TTC #1 Since Aug. 2013
    Cycle 1: O CD 25=bfn
    Cycle 2: O CD 48=bfn
    Cycle 3: Anovulatory/Provera =120 days!
    Cycle 4: Anovulatory/Prometrium=127 days! RE consult 6/16
    Me: Anov/poss. pcos?  HSG=normal/SA= Normal 
    July/Aug. 2014= Femara+trigger+TI=BFP!!
    Beta #1@ 16dpo=626!! Beta #2=1510
    Ultrasound @ 5w6d=heartbeat at 110!
    Ultrasound @ 6w6d =heartbeat at 131!


    Pregnancy Ticker

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  • Like @catlover790, I have read that ladies with PCOS do have the higher levels of LH so even a slight increase in LH will trigger a +OPK, but that increase is not enough to trigger ovulation in a PCOS-er.  Does that make sense?  Has anyone else heard it explained that way?

    I don't know if that is helpful.  You said you never got a +OPK so perhaps you never had that increase in LH?  The RE will be able to monitor you frequently enough to tell you what is going on for sure.  

    Good luck with your consult!  My consult was an introduction with an overview of a preliminary plan.  My RE got all of my records and reviewed them before my consult, so she had an idea of the direction we should go.  I would get those ob/gyn records to the RE's office asap, if you haven't already.  They will want to update most of the tests which may be cycle day specific.  If so, you'll wait for AF (or trigger AF if you're as irregular as I am!) and do bloodwork on CD 2-4 and other tests on CD 5 - 12.  This will give the RE a baseline from which to work.  They'll also probably want your husband to do or redo his SA.  After all that is done, I'm not too sure what happens because I haven't gotten there yet.  Good luck!!!

    Me: 28  MH:35

    Married September 2012. TTC since September 2013

    June 2014 - Dx w/ significant PCOS and referred to RE.

    July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+

    Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN

    Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN

    Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN

    WTF consult scheduled for 1/29

  • On your medicated cycles, the 2 days of OPK+ is really normal - the timing of your testing each day could have caught the beginning and the end of your surge.

    In the cycle where  you had a CD21 progresterone of 21, that indicates O occurred. It's always possible to miss the surge during the day if it happens to be short (again, can be normal) or if the urine isn't concentrated enough.

    Since OPKs have not been friendly to you, it makes tons of sense to request a trigger shot. Actually, although I did not use a trigger for my first medicated IUI cycle personally, almost everyone on this board does.

    I hope working with an RE relieves some of these concerns and gives both of you some renewed hope and energy for this process! We certainly felt better after getting testing and a plan with the RE.

    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Everyone else covered it. So good luck at the RE!
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