Trouble TTC

Disappointing IUI#1

At my HSG last month, after RE couldn't get the catheter to my uterus (he ended up injecting the dye from the cervix), I was nervous about IUI, but he insisted that the firmer catheter used for IUI would work fine.

This morning, after more than 20 excruciating minutes of cervical abuse, the nurse finally transferred the sperm to a different catheter and performed an ICI instead!

I'm so unhappy after reading the much lower success rates of ICI compared to ICI. And DH's sperm had only 44% motility poast wash (though the 22 million motile post wash blew me away).

I feel like our chances are tiny this cycle, since the things that normally help increase chances didn't happen - I ended up with one follicle (and I already O each month anyway), no IUI, and DH's last two SA's had come back with 70% motility without any wash. Only real difference I see in this first treatment cycle is that I went on Estrace for a thin lining (I'm on Letrozole/Femara, which I don't think thins a lining, and I have really short, light periods, so it makes me think I had that problem to begin with). Happily, my lining was almost 10mm today. 

Well, I always told DH we are "just practicing" to avoid disappointment. I just need to make sure he doesn't feel like this cycle is a waste because I'm afraid he's not going to want to move to IVF when/if it's time.

I have a couple questions: Is it normal for them not to do more rounds of washing to cut down on immotile sperm, since the count was clearly good enough, and would a 44% motility harm IUI chances? Also, has anyone had that procedure where they dilate your cervix before IUI (the nurse mentioned maybe this for next time), and does it need to be done every cycle, and is there any pain meds or anesthesia? Thank you so much in advance for sharing your experience! I kind of felt like crying, but then got a despondent, "well what do I expect, this is our hopeless TTC journey after all" kind of feeling.
January 3T Siggy Challenge - New Year's Resolutions
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Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
IUI #5.1 - Jan (Bravelle) Cancelled 
Planning to start IVF in March!
***All Welcome***

Re: Disappointing IUI#1

  • Awww, I'm so sorry! I don't really have any answers for you, but I can see why you would be disappointed. I try to frame each cycle as an opportunity for us to learn about my body in hopes that we can make improvements for the next cycle. I know that doesn't really make the disappointment go away though. I hope you guys can figure your cervix issue out. ((hugs))
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


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  • I'm so sorry your IUI was disappointing. I don't have any advice but I wanted to give you a big internet ((HUG))

    Me-36
    DH -35
    Married in 2008
    Started TTC in 2011
    Began testing May 2014
    Test Results
    HSG- clear
    Hysteroscopy- clear
    SA- 11 mil count
    45% motility
    Diagnosis: MFI
    July 2014: Femera 5mg CD 4-8, Trigger, IUI = BFN
    August 2015: Femera 5mg CD 4-8, Trigger, IUI = BFN
    September 2015: Femera 5mg CD 4-8, Trigger, IUI = BFN
    May 2018 after long period of not trying, starting adoption process with family friend's newborn
    November 2018 Adoption complete!


  • BunnyBerryBunnyBerry member
    edited June 2014

    @lebradford Thanks, that does help a lot to hear! I'm sorry, too, that your IUI#3 isn't working out as you planned. Actually, I definitely needed to remind myself that this kind of thing is just a hiccup in the road, not the end.

    @caterinac Oh, I'm so sorry! The bleeding was scary but I was also glad in a way that DH was there to see all of that because I needed him to know how hard this is, not just like, Oh and then they put your happy little spermies in my uterus. Also, great practical advice. I tried to empty my bladder for comfort (and by the end I honestly thought I was going to start peeing from all the pressure) but if it helps get the sperm there.... I also want to know why she never bothered with the ultrasound machine, it was right there??

    @daydreamsam Oh ouch, I'm so sorry! I had heard that kind of thing about the cervical dilation before, and I am almost as petrified of the procedure as I am of nothing ever, ever getting to my uterus!! I am going to share your experience of the softer catheter with my RE. I was really unhappy that the nurse doing the procedure had no idea of what happened during the HSG - it could have saved us a few steps I'm sure. And RE had also assured me a doctor would be in the building to help make sure the procedure would work well, but the nurse never asked him to help, so I have a few things to add to my WTF if it's needed. :(

    @awiley10 Thank you. Just woke up from a nap and it was this beautiful surprise to see all these encouraging words. :)



    January 3T Siggy Challenge - New Year's Resolutions
    image
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    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • No advice here either but I am sorry things didn't go as planned. Are you able to call you doctors office and speak to your assigned nurse and get some answers just so you can be informed in case this process doesn't work as we all want it to for you. Sometimes I felt that I would save all my questions not to bother our nurse and wait to see if it was a bust, but then I felt rushed to get my questions answered prior to the next cycle. Not sure if that makes sense, but I will add you to my prayer list so count on some extra coming your way! {{Hugs}}

    **June Celebrity Crush**
    imageimage

    ~*~*~ ALL ARE WELCOME & GREATLY APPRECIATED~*~*~

    TTC since October 2012

    Went to OBGYN in August 2013-Referred us to UCONN RE in September 2013

    Me (31):  Blood / Ultrasound / HSG / SIS- All Great  -  DH (32): SA is very low

    DH met with Urologist nothing is "wrong" just very low count and low mobility

    RE 1st Consult October 31, 2013 - Male Infertility Dx.

    RE Appointment on 1/15/14-Decided on 1st IUI

    IUI Cycle #1-Clomid 50mg 2/14-BFN

    We decided to take a break for 3/14-4/14

    IUI Cycle #2-Clomid 50 mg 5/9-BFN

    IUI Cycle #3-(RE Office called us in for a back to back IUI for another SA) 5/12-BFN

    *Husband's count is still very low post wash however after 4+ months on supplements, vitamins, and a healthy lifestyle (aka no beer)  his mobility has doubled! I am very happy for him, small victories!

    May 2014-RE wants us to progress to IVF as 3 failed IUI's.

    IVF Seminar meeting on 6/12 & then meeting with RE on 7/9 to come up with our plan for our miracle baby!

  • @amazing817 That is really wise advice. I was just thinking to hang on to the questions for later, after the beta, but you are totally right - that is just adding more stress and why shouldn't we be free to get some answers instead of one more thing depending on whether I start bleeding in 2 weeks? (Sorry, feeling a bit bitter.) Thank you so much for your prayers!!!
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • I'm sorry that you and your cervix went through so much :( I've never had a problem with IUI because my cervix was soft and open but I've heard of woman being dilated. I think they just use a metal dilator before doing it and it doesn't require any meds I'm pretty sure. One of my friends had to have it done for her HSG and said it was uncomfortable but didn't last long (no where near as uncomfortable as the actual test). I hope that your ici works but if not, you should definitely look into dilation. FX for you!



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

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    Pregnancy Ticker




    March 15 Siggy Challenge: You had one job

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  • @lillovebug79 Thank you so much for sharing that, I was just kind of assuming that the dilation procedure would be equally drawn-out and uncertain. Oh, how I hope a quick easy dilation is the answer. Thank you for the kind wishes. :)
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Ouch!  I'm so sorry you had to go through that!  I don't know anything about the washing, other than it happens.  At the very least your lining if pretty awesome so if nothing else you did have that positive outcome this cycle.
    image
    Me:36 DH:40
    Married since May, 2012; TTC since September, 2012
    DX: Blocked Fallopian Tube, Hashimoto's
    March 2014 - Clomid, Trigger, TI = BFN, April 2014 - Clomid, Trigger, TI = BFN, May 2014 - Clomid, estrogen, trigger, IUI = BFN, June & July 2014 - Natural cycles = BFN, August 2014 - Femara, estrogen, trigger, IUI = BFN, September 2014 - Femara, estrogen, trigger, IUI = BFN
    Prepping for IVF in with ER/ET slated for early February


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