Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).
We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).
Re: Giving up on IUI? Time for IVF?
2008: HSG (normal), couple rounds of clomid through gyno
2008 - 2010: dragging my feet out of fear and procrastination
October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
Oct. 2010 - Dec. 2012: In DENIAL! avoided the issue because I was scared of surgery
January 2013: returned to RE, fibroids grew significantly
February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
March 2013: MRI to determine what type of surgery may be necessary
July 29, 2013: fibroids (5) removed via robotic laparascopy
August 2013 - Nov 2013 : benched due to recent surgery
IUI #3, Feb. 25, 2014 BFN
IUI #4 canceled due to lack of response to letrozole
IUI #4.1 April 28, 2014, BFN
May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis
May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
October 2, 2014 - started metformin treatment
November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5
November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)
IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN
We are done with treatment unsuccessfully.
Edited for spelling!
********Siggy/Ticker Warning***********
Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
Dx MFI with low to normal count, low motility, morphology 3%
HSG normal, ultrasound and labs on me all normal.
1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
Started seeing an RE!!
2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
IUI #5 natural cycle (needed a med break) = BFN
IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN
Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).
Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
Holy crap BFP!!!
Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!! First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!
PAIF/SAIF/All Welcome!
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March 15 Siggy Challenge: You had one job
TTC since 08/2012
DX: DOR
Good luck!
Here is why...
1. We are a same sex couple using donor sperm. $300 per vial and we have one left. We had decided previously to go all out for the last one. Could we buy more? Yes. Do we want to continue to do that? Not unless absolutely necessary. Also, if the donor we like gets low or sells out, then we have to find a new one. I really like the one we have now...based on the information we have anyway.
2. We moved to injects, which I respond well to...too well in some cases. We have cancelled 2 IUIs because of over responding. We live 1.5 hours from the RE's office. To put all that time into a cycle and not even get a chance is crushing. IVF is much more controlled...we aren't interested in the risks of HOM.
3. We want a baby (I know, we all do!) and like the odds of IVF better. My RE estimates a 60% chance that I will get pregnant and deliver a healthy take home baby. I like those odds way better than IUI odds. I'm ready to move on from the getting pregnant part to the being pregnant part. Though I do recognize that IVF is not a "cure all" for everyone.
4. I have endometriosis and that can interfere in all sorts of ways. IVF skips over all of that.
We have been talking about IVF since January, so it was not a decision we made lightly. The morning that we walked out of the RE's office when we knew IUI #6 was going to be cancelled, we were both exhausted. I was near tears. I looked at C and said that I wanted to go to IVF. She agreed and that's the path we are on now.
ETA: A few days ago, C said that she wishes we would have just done IVF to begin with, or at least after the first 3 IUIs. It was a hard decision due to the difference in insurance coverage
though. Had we been OOP from the beginning, we would have done IVF much sooner.
Me: 30 DW (aka C): 29
Together since 2/15/11 ~ Legally married in NY on 9/29/12
***CP mentioned***
We've been working on baby #1 since July 2013 using Open ID donor sperm. 8 IUI attempts with 5 actual IUIs and one chemical pregnancy. We have one fresh IVF cycle under our belts as well as a FET. I have endometriosis and a uterine septum that was corrected via surgery in November 2013.
11/14/14 - Second HSG shows that tubes are still clear and ute is looking good.
12/6/14 - Started BCPs in prep for IVF #2
12/22/14 - Saline u/s and endometrial scratch (All was clear and OUCH!)
1/2/15 - Began stimming for IVF #2
****All Welcome!****
We are Mommas to four fur babies - 3 dogs and 1 cat.
ME - 31, DH - 40
Married 06/25/2011, TTC since 03/2012
BFP #1 on 11/13/12 -- EDD 7/24/13 -- M/C (CP) on 11/21/12
BFP #2 on 7/21/13 -- EDD 3/29/14 -- M/C (CP) on 7/31/13
09/4/13 - 4/16/14 -- IUI #1 - 6 = BFNs
7/13/14 -- IVF #1 w/ ICSI
ER on 7/26/14 -- 20 R, 15 M, 11 F
ET on 7/31/14 -- 1 transferred (4bb); 8 frosties!!!
BFP #3 on 8/8/14 -- EDD 04/18/15
BETA #1: 473, BETA #2: 1009, BETA #3: 1975
** It's a BOY!!! **
These are all really thoughtful and helpful responses. I really appreciate the community here. I think this will be our last IUI cycle, and I feel like it's the right decision. I'm Canadian, and in my province, IUI is covered while IVF is not, and while I have additional private insurance, it does not cover any fertility treatments... so IVF will be entirely out of pocket. In addition, we're using donor sperm (we're a same sex couple), so that's another expense, although it's already paid for at this point (3 units left). While IVF is expensive, the barrier for me has always been less about the money and more about the fact that IVF seemed invasive and scary. Then again, the stats are so much better. Our clinic tells us that with a single embryo transfer, the odds of a pregnancy are about 50%, going up to 70% with two transferred. This sounds about in line with what others on this board have said, but since we're in Canada, I don't think there is any information like what you have with SART. I think that repeated IUI can be very emotionally draining if it drags on and on (as it has for me without any success whatsoever). The only other option my doctor suggested at this point would be laproscopy to address potential endometriosis (suspected due to cysts, but I have no other symptoms such as pain), followed by more IUIs. Frankly, I don't want to go through another six months of IUIs only to find out I will need to do IVF anyway. IVF will also give me more clarity regarding my suspected egg quality issues (low AMH). So it seems like the best choice. I've given it a fair shot with the IUIs but enough's enough. Moving on!! Thanks for your support and wish me luck .
Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).
We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).
Trying since Jan 2011. Unexplained IF.
2 IUIs = BFN.
1 IVF (Dec 2013) = BFN.
FET, 2 frosties (June 13, 2014)
14dp5dt-June 27 -BFP, beta 2061. 2nd beta >5000, 3rd beta >5000, 2 sacs 06/30.
Twin Girls - 02/11/15 - at 37 weeks (no NICU, home with me at 3 days).