Trouble TTC

cancel or trigger?

damn it...

My nurse just called. I have 4 follies at 16mm and 2 at 15mm. I didn't ask for exact e2, but she said it rose appropriately

The RE said I can trigger tonight, IUI Sunday or cancel.

So, triggering tonight may mean no mature follies or high multiples. The nurse seemed to think that bc follies continue to grow after trigger that maybe some would mature, but maybe not...but if all mature, that's a shit storm too

And canceling just plain sucks

Ugh. What would 3T do??

4 Losses (2003, 2008, Apr 2012, & Oct 2012)
All RPL and IF testing with multiple REs = normal

5 IUIs = BFN

All AL are welcome
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Re: cancel or trigger?

  • MissEm15MissEm15 member
    edited May 2014
    I was in your exact same situation last month.. I ended up 5 mature and two more borderline. I had the option to trigger when the lead two follicles were at 16.5mm but I decided to wait bc at that time I was okay w/ an IUI w/ 4 follicles. I was not okay w/ IUI w/ 7 however so we cancelled. We did go ahead w/ TI (we are MFI too that is why). It was a BFN. Looking back, I would have triggered w/ the two almost mature to at least have some hope instead of none from a cancelled cycle. The risks are up to you tho & you need to be comfortable w/ whatever the outcome. I wish you the best luck and peace w/ your decision!

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

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  • I think if I was ok with selective reduction, I would do it, and if I wasn't, then I would cancel.

    I'm sorry you have to decide. :-(
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • Thanks for your responses, ladies

    We're going to trigger tonight, IUI Sunday

    *sigh*

    4 Losses (2003, 2008, Apr 2012, & Oct 2012)
    All RPL and IF testing with multiple REs = normal

    5 IUIs = BFN

    All AL are welcome
    Image and video hosting by TinyPic

  • Wow with 6 follies all in the same range, I would definitely not trigger, IUI or even TI.

    I would feel that is just asking for trouble.

    Looking at your sig, those MFI #s seem less than average for good IUI chances, but certainly not awful for IUI, and it's always possible that the count on IUI day (or even TI day) could have a random improvement.

    But my #1 reason would be what it would do to me emotionally to have to wait out the TWW. I'm sure by the end I'd just be praying that nothing happened rather than the risk of multiples.

    Of course, we all have different thoughts/feelings when it comes to selective reduction. For me, I hate the thought of it, but I would probably feel somewhat okay about it for health/safety reasons if I had a fluke HOM - like, identical twins or invisible follie or something. (And if we never had success and then I learned that I have really poor egg quality or something, then I would also not feel like I'd made a horrible mistake if I tried with 3 or 4 or something and got HOM.) But I would not want to put myself in a position where I felt like I had taken a serious known risk and then having to deal with the results.

    Would your RE be willing to go through the risks as they apply to your individual diagnoses and history? Perhaps you'll find that in your situation, risk of HOM are still extremely low. I would want as much info as possible before having to throw away a cycle.

    Good luck with whatever you decide! I'm so sorry that you are in this position. Do you feel comfortable that your RE made wise choices about your injection protocol, and this was just an unlucky surprise?

    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Wow with 6 follies all in the same range, I would definitely not trigger, IUI or even TI.

    I would feel that is just asking for trouble.

    Looking at your sig, those MFI #s seem less than average for good IUI chances, but certainly not awful for IUI, and it's always possible that the count on IUI day (or even TI day) could have a random improvement.

    But my #1 reason would be what it would do to me emotionally to have to wait out the TWW. I'm sure by the end I'd just be praying that nothing happened rather than the risk of multiples.

    Of course, we all have different thoughts/feelings when it comes to selective reduction. For me, I hate the thought of it, but I would probably feel somewhat okay about it for health/safety reasons if I had a fluke HOM - like, identical twins or invisible follie or something. (And if we never had success and then I learned that I have really poor egg quality or something, then I would also not feel like I'd made a horrible mistake if I tried with 3 or 4 or something and got HOM.) But I would not want to put myself in a position where I felt like I had taken a serious known risk and then having to deal with the results.

    Would your RE be willing to go through the risks as they apply to your individual diagnoses and history? Perhaps you'll find that in your situation, risk of HOM are still extremely low. I would want as much info as possible before having to throw away a cycle.

    Good luck with whatever you decide! I'm so sorry that you are in this position. Do you feel comfortable that your RE made wise choices about your injection protocol, and this was just an unlucky surprise?

    We did decide to trigger, but in regard to your question about the injection protocol...

    No, I don't feel like my RE made a wise choice. Last IUI, we ended up triggering on cd 9 as well (today is cd9) bc we had 1 follie that was 18, but quite a few at 16. Knowing that I responded like that, my DH and I assumed that my dose would have been lowered to begin with, but decided to trust in the REs decision this cycle

    Of course we would discuss it if we don't get a bfp this cycle, but actually that RE is leaving in 2 weeks, and a new one starting

    Again, *sigh*

    4 Losses (2003, 2008, Apr 2012, & Oct 2012)
    All RPL and IF testing with multiple REs = normal

    5 IUIs = BFN

    All AL are welcome
    Image and video hosting by TinyPic

  • It is all just a crap shoot. I have gone ahead with 3 mature and a 4th close...got triplets. On another cycle I had 3 mature and got a BFN...and another time I had 2 mature and 2 close got a BFN, my second pregnancy was 2 mature...they were the same size even, and I got 1 baby. You just never know. I myself can not do selective reduction unless it was more than quads...but that is just me. Fingers crossed you get just one, or two. A HOM pregnancy is nothing to sneeze at, but there are great Doctors out there that can do their best to get everyone through safely. Good luck!
    photo 203b9128-895f-464c-a378-ff73eaf8c1ce_zps4de57ab1.jpg
    Xander, Hayden & Lily 5 1/2 and Jericho 3 My Blog!
  • MrsM429MrsM429 member
    Thanks for your responses, ladies We're going to trigger tonight, IUI Sunday *sigh*
    Good Luck! I would have made the same decision

    Me: 27 (PCOS/Hashimotos/Irregular Cycles) // DH: 38 (MIF- low count/motility)

    Married: 4/29/11

    TTC: Since 10/2011

    3 CP (3/2011, 11/2011 & 6/2014)// HSG 5/14: ALL CLEAR!


    10/2012: 100mg x2 Clomid/IUI: cancelled due to poor response (stubborn follies)

    02/2013: 200mg Clomid//IUI: 2 follicles (21mm &19mm) / 1.3m P/W= BFN

    04/2012: 200mg Clomid/IUI: 1 follicle (20mm) / 1.6m P/W= BFN

    10/2013: 250mg Clomid/IUI: 1 follicle (23mm) / 4.5m P/W= BFN

    02/2014: Follistim/B2B IUI: 1 follicle (23mm)/ #1: 2m P/W & #2: 800K P/W= BFN

    05/2014: 50mg Clomid/Follistim IUI: 3 follicles (21mm, 15.5mm & 15.5mm)/ 4.7m P/W= CP

    On a TTC break for 3-6 months while DH gets treatment with a Urologist


  • Good luck!
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • rella22rella22 member
    I would have/did make the same decision last month and a BFN. Good luck and I hope you have a different outcome!

    ***SIGGY WARNING***




    me: 28 - all test normal
    DH: 33 - SA normal

    *unexplained*

    TTC since September 2011
    2011-Oct.2013 - trying off and on, ob/gyn, no meds
    November 2013-December-EOD, ob/gyn, no meds

    January 2014- ob/gyn ordered Clomid (50 mg) unmonitored, EOD-BFN
    February-Clomid 50 mg. unmontiored, EOD - BFN
    March-Switched to RE
    April- 100 mg Clomid/Ovidrel-BFN
    May - 100 mg Clomid/Ovidrel-BFN
    June-*BREAK/Switch RE*
    July- 5 mg Femara/Ovidrel + IUI #1- BFN
    August- 5 mg Femara/Ovidrel + IUI #2 - BFP!!!!

    EDD: May 7th, 2015: Team PINK



  • I see you triggered already. Sending you hugs I know it's frustrating, hope it works out this cycle.

    Lilypie Angel and Memorial tickers

    TTC: Started May 2012
    Bloodwork - potential ovulation issue which seemed to be fixed by clomid.
    SA - Mot (36%) and count low 9.3 mil (updated) 
    HSG - Oct 16 2013 - came back clear
    Clomid #1 - Nov. 2013 - BFN
    BFP#1 =  Clomid #2, Dec. 2013 - EDD 9.9.14 Loss Jan 9
    Femara #1 + Trigger (2/21) Feb. 2014 +ruptured ovarian cyst - BFN
    SIS clear
    April 2014: 50IU Follistim CD3-CD9 + 25IU CD10-CD13+CD13 trigger 1 mature follie= BFN
    IUI #1: May 2014 50IU Follistim + trigger + IUI = BFN
    IUI #2: June 2014 50IU Follistim + IUI (3 mil sperm)=  BFN
    TI #2: June 2014 50IU Follistim  + Trigger = BFN
    BFP#2 = IUI# 3: Aug 2014 75IU Follistim+ Trigger + IUI (2 mil sperm) EDD May 15

    BabyFruit Ticker


    image
     Love bugs unite!
    Daisypath Anniversary tickers

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