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Thin Lining - how thin is too thin?

JessarabJessarab member
edited May 2014 in Third-Party Reproduction
My transfer has been pushed back three different times (three weeks in a row) due to a thin lining - it's currently a 6.5mm and my RE wants to see a 7.5 before we schedule the transfer. I have been taking baby aspirin, prenatal vitamins, estrace and I've been using vivelle dot patches. My hormone levels are right on track but the lining just isn't getting thicker. I had an endometrial scratch last week in hopes to thicken the lining - has anyone else had this? Did it help? 

My RE has said that if we can't get it thicker, we'll have to cancel the cycle. Considering I'm on a bit of a time crunch, I can realistically only cycle twice more. Anyone else have a transfer with a thin lining resulting in a little lovebug?
Pregnancy Ticker

Married September 3, 2011 | TTC since May 2013
Me: Diagnosed with ovarian cancer in 2013, underwent fertility sparing surgery which left low ovarian reserve, no tubes, partial ovary | DH: perfectly normal 
BFP: 5/30/2014 via donor eggs | EDD: 2/6/2015
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Re: Thin Lining - how thin is too thin?

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  • J&D2007J&D2007 member
    I think some RE want above 7.0 and some above 8.0. I think my only PGD normal fresh transfer was a failure because mine was just over 7. I know it's very hard to wait or cancel, but you don't want to look back and wonder if you should have.
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
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  • daydreamer34254daydreamer34254 member
    Sorry to hear that your lining is causing you so much stress. My lining has always been borderline... it has always gotten there, but it was stressful every step of the way. Out of our three IVF egg retrievals, we have only ever had one blastocyst. We did a FET in April, and of course my lining was stubborn. It just barely made it over 7, but I told the doctor that if things weren't absolutely ideal that I'd prefer to cancel and try again with another cycle. After all we went through to get one blast, I didn't want to squander our chances! 

    Like PPs said, I drank POM juice every day and ate Brazil nuts. I also was switched to 2mg of Estrace three times a day taken vaginally. It worked! I got a lining over 7, and the pattern was good! Sadly the cycle resulted in a BFN, but I have no regrets about my lining. I know we did our best.

    Good luck!!
    image
    TTC since March 2012
    Dx: Unexplained IF, Arcuate Uterus, Minimal Endometriosis, Poor Embryo Quality
    Tx History: 1 Injects+TI, 5 IUIs, 3 IVFs, 1 FET = all BFN and full of heartbreak
    Plan: Waiting to see if our potential donor is a match for DE IVF #1


    Pain is inevitable. Suffering is optional.
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  • JessarabJessarab member
    Thank you all for the advice and support! I did start the estrace vaginally so I hope that helps :) I have a follow-up appointment tomorrow for another lining check, so fingers crossed this week was just what I needed! If not, I plan to start drinking some POM and trying acupuncture... I'll pretty much try anything :)

    Happy almost Friday!
    Pregnancy Ticker

    Married September 3, 2011 | TTC since May 2013
    Me: Diagnosed with ovarian cancer in 2013, underwent fertility sparing surgery which left low ovarian reserve, no tubes, partial ovary | DH: perfectly normal 
    BFP: 5/30/2014 via donor eggs | EDD: 2/6/2015
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  • Twinkie0612Twinkie0612 member
    Lining problems is the one issue I never had.  My current clinic looks for at least 7mm, but my previous clinic wanted over an 8. I know some women do better with delestrogen injections over vivelle or estrace.  Also I've known a few women who took viagra suppositories and/or Terbutaline (sp?) to help with lining issues. I've also heard of some women who have to take stims in order to build a lining.

    imageimageimageimageimage

     

    image

    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

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  • chicagobride_07chicagobride_07 member
    My RE did not use lupron with me for any of my cycles. I did take the BCP for a cycle before starting estrogen. I've used delestrogen injections and they seem to work well. They are my REs preference. Best wishes to you.

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

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  • JessarabJessarab member
    @jenek0213 - interesting on the lining increase once off lupron! I've been on it for over 40 days so I wonder if that had any affect.

    I have such good news to share - the endometrial scratch worked! My lining is triple stripe, 7.5mm as of this morning. We have officially gotten a transfer date of Tuesday or Thursday depending on 3 or 5 day embies. I can't believe we're finally moving onto the next step. Tomorrow starts the PIO injections, here goes nothing!

    Hope everyone has fun weekend plans!
    Pregnancy Ticker

    Married September 3, 2011 | TTC since May 2013
    Me: Diagnosed with ovarian cancer in 2013, underwent fertility sparing surgery which left low ovarian reserve, no tubes, partial ovary | DH: perfectly normal 
    BFP: 5/30/2014 via donor eggs | EDD: 2/6/2015
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  • katie_71208katie_71208 member
    I've always had a thin lining. For my de transfer I just barely got to 7 (and that was on the donor's retrieval date...I know they actually like to see 7 before that day) I was really worried about it but it worked! I was on estrace orally 3x per day and vaginally 2x per day.
    29 yrs. old w/ DOR & LPD: Highest FSH 30, AMH 0.16, low antral follicle count
    IUI#1 w/ Clomid, Trigger, and Crinone: BFP 9/12/12, EDD 5/24/13, mm/c 10/13/12, Testing done = Trisomy 16
    IUI#2-8 (injectables): BFN
    IVF #1- April 2013: Only 1 follicle on max stims- Converted to IUI: BFN
    DE IVF#1: BFP!! EDD 11/20/14
    BabyFruit Ticker
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  • DoulaRaVenMaDoulaRaVenMa member
    Big congrats!! That's great news, sending you lots of baby sticky dust for your up & coming transfer!!!

    I hope to transfer next week as well
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  • daydreamer34254daydreamer34254 member
    Good luck, good luck!!!
    image
    TTC since March 2012
    Dx: Unexplained IF, Arcuate Uterus, Minimal Endometriosis, Poor Embryo Quality
    Tx History: 1 Injects+TI, 5 IUIs, 3 IVFs, 1 FET = all BFN and full of heartbreak
    Plan: Waiting to see if our potential donor is a match for DE IVF #1


    Pain is inevitable. Suffering is optional.
    Report Reply
  • Rlipman22Rlipman22 member
    We had several IVF cycles that were cancelled due to thin lining. We finally used vaginal suppositories of Viagra and achieved a lining superior to all of the extra estradiol that they could pump into us:)
    Report Reply
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