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Those who've had RPL testing (re: MTHFR)

Lucky428Lucky428
in Miscarriage/Pregnancy Loss

What was your diagnosis? I have homozygous MTHFR C677T and Hashimoto's.  For the MTHFR, I just take baby aspirin and folgard because my homocysteine levels are normal.  For my Hashimoto's, I take Levoxyl and my endocrinologist monitors me very closely.  Both my RE and my perinatologist determined I won't need Lovenox shots during pregnancy, but after 3 losses, I just don't know what to do.

Does anyone else have this? What do your drs say? 

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Re: Those who've had RPL testing (re: MTHFR)

  • Anna&MattAnna&Matt member
    Well let me preface this by saying I tested negative for all of the clotting disorders BUT I had a DVT last year. I had 3 veins that were totally blocked in my leg so we are going to do lovenox shots the entire pregnancy next time until 35 or 36 weeks and then switch to heparin so I have the option to get an epidural. There are mixed feelings about lovenox during pregnancy and every specialist I've seen has said something different but my OB and I talked through the options and decided it's better to be safe than sorry so I will take 40 mg Lovenox (1 injection) daily. Lovenox really sucks (stings like hell) but if you put ice on it right afterwards that helps considerably. I highly recommend getting at least a 2nd or 3rd opinion and then weighing the pros and cons and deciding what you want to do. If you have any Lovenox type questions feel free to pm me or page me.
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  • Lucky428Lucky428
    Thank you so much.
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  • Temp893722312503334Temp893722312503334

    My MTHFR protocol is the same as yours but I get my homocystiene levels checked each cycle.  I may need  to do lovenox as well once PG but that is for my Factor V not MTHFR. 

    I think your plan sounds good. I may take Lovenox just to be safe anyways too. 

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  • KarlsSweetie05KarlsSweetie05 member

    I have hetero MTHFR A & C (I think) and Hashimotos.  I take a baby asprin and folguard too and thyroid med too. 

     My RE checked my homocystine levels a few times during this short pg and they were "excellent" so she wouldn't give me the lovenox.

    But I obviously lost this pg early so I am wondering if I actually do need it.

     My thyroid has been fabulous too,but RE mentioned that women generally need to increase their dose of thyroid meds as the pg progresses as the baby uses your thyroid and you have to supplement to keep it at an even keel.

    TTC #1 for over 5 years - too many to count IF treatments (tried everything and anything), repeat miscarriages. Finally, Sticky Success!! B/G Twins arrived 2011. VOTE on my Name List Baby Birthday Ticker Ticker
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