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IUI# 1 Down, Frusterated

LindseyNicholle84LindseyNicholle84 member
in Trouble TTC
Hi Ladies, 

A little about me first since I am to this. My husband and I have been ttc for almost two years now. We have done four rounds of clomid with one of them being an IUI. I am currently 3 days before my scheduled AF and I am spotting. No other period symptoms. I took a pregnancy test yesterday and it was negative. I am so tired of being heartbroken every month. The doctors say that both my husband and I are very healthy. I hate not being able to understand why we can't seem to have a baby. It almost seems like it is easier for other people and so hard for some. I can't help but get angry. Lately I have just felt like throwing in the towel. 
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Re: IUI# 1 Down, Frusterated

  • jencity9jencity9 member
    edited May 2014
    Sorry about your BFN. We all know the feeling of that frustration and the renewed hope we get at the start of every new cycle. What is your diagnosis, or is it unexplained IF?

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary
    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN
    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis
    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5
    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)
    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

    image    image
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  • Pintobean39Pintobean39 member
    I'm sorry ((hugs))
    Fucking bump!!!!
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  • tumbleweed123tumbleweed123 member
    I'm so sorry - I totally understand how you feel.  Just know that you aren't alone!  (((hugs))) and FX for you.  
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  • Lillovebug79Lillovebug79 member
    I'm sorry! I know it's hard, I think all of us on here have been or currently are in the same position. The disappointment is so much worse the more invested you are in a cycle. It definitely takes a toll, emotionally, financially, physically, and all the time you invest. Unfortunately, all we can do is hope that the next cycle will be different. There is so much that is out of our hands. Good luck and I hope AF isn't on the way!



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!


    PAIF/SAIF/All Welcome!

    image




    Pregnancy Ticker} 




    March 15 Siggy Challenge: You had one job

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  • modernfairytale8709modernfairytale8709 member
    I'm sorry you're experiencing this. IF blows.
    BabyFetus TickerBabyFruit Ticker
    imageImage and video hosting by TinyPicImage and video hosting by TinyPic
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  • lebradfordlebradford member
    I'm sorry. :-( I know it doesn't fix everything, but you're not alone.
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


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  • LindseyNicholle84LindseyNicholle84 member
    Thank you for the replies. Its unexplained but for some reason my doctor isn't doing an HSG test. I think I am going to push for one. I am surprised she hasn't done that to rule out a blockage. Its also hard because husband is trying to be supportive but I know he is just as frusterated. 
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  • BunnyBerryBunnyBerry member

    So sorry, what an awful place to be in (I hate spotting hell).

    Kudos to you for asserting your right to an HSG!!

    Ditto PPs, if you're not already seeing an RE, they might be able to give you some clues better than an OB/GYN.

    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009 | RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
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  • TVLilyTVLily member
    So sorry for the BFN, IF is a witch. ((Hugs))

    EDD 5/2/14, NMC 9/11/13
    EDD 10/15/14, CP 2/8/14
    IF Diagnosis: PCOS, MFI 

    Current Cycle: 5 mg Femara/1000mg Metformin + TI = BFP, EDD 4/23/15 Please be our RAINBOW

    image

    **ALL AL/IF Welcome**
    My Chart

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  • LindseyNicholle84LindseyNicholle84 member
    I am being monitored while on clomid yes. I have been getting an increase in folicles every month. This last cycle had two really good ones and two small ones. I just send an email to my OB/GYN on her thoughts for the HSG. A part of me feels like there is something that isn't quite right. I have never had a pregnancy scare ever and before I was really proud of that.. now I am wondering if there is a reason.
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  • [Deleted User][Deleted User] member
    I would recommend seeing an RE, and getting the HSG done to check your tubes.

    I'm so sorry for your bfn :(
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  • Waterlily234Waterlily234 member
    I am so sorry for your BFN. I agree with previous posters, I am sure you are very healthy and hubby too but after two years, why NOT have the HSG and a hysterosonogram to make sure there is nothing structurally going on there? Also your spotting a few days before AF is due might be something to bring up as well. Have you had day 3 and day 21 b/w done? Has hubby had an SA? I hope you get some answers, TTC is the worst.  Hugs!

    ME:      36, on BC since 1996,  irregular periods.   HUBS:      37, healthy

    2001—meet.  2005—marry.  2006—Furbaby is born. 

    On BC till end of 2009.  2010 NTNP.   

    New Year’s Eve 2010—BFP?! January 13, 2011—early loss, HCG peaked at 324, no D&C needed.

    +++++

    Feb 2011-Nov 2012—NTNP 

    Dec 2012 --present (TTC 20 months) Not even a hint of a BFP

    Me:  BW, U/S, HSG, HSN normal.  AMH 2.33.  Hubs: SA normal 

    +++++

    April 2014--IUI #1 Clomid 100 4-8 Follistim 150 9-14, 5 mature follies at trigger, Peak E2 5/5 1100, BFN 

    May 2014 ---IUI#2 Clomid 100 3-7 Follistim 150 8-13, 3 mature follies at trigger, Peak E2 6/6 547, BFN

    June 2014--IUI#3 Follistim 150/225 3-15, 3-5 mature follies at trigger, Peak E2 7/11 1450, BFN

    July 2014--IUI#4 Follistim 225 2-12, 3 mature follies at trigger, Peak E2 8/12 841, BFN

    Breaking till after Christmas, then IVF...taking 4000 mgs daily Inositol and Melatonin 3mg


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  • nswain85nswain85 member
    I'm sorry that you are having a hard time right now :( This ride is such an awful one sometimes! I think you are right to want to push the HSG and hope that it leads to some answers for you. I would also look into getting in with an RE, you might be able to bypass some waiting around time and get straight answers. Best of luck!

    Trying to have baby #1 since April 2013

    DH SA March,May 2014 - Low motility and shape issues. On vitamins per RE to help

    Me testing April 3, 2014 - FSH and LH good, HSG showed blocked right tube

    April 29, 2014 - First RE appt., right tube needs to be removed and possibly left also if

    it's bad too. RE suggests going straight to IVF

    June 4, 2014 - LAP/HSC and unexpected endo. removed but tubes got to stay!

    June 13, 2014 - Post-Op appointment. We decide where to go next since main issue

    is MFI influenced. Trying naturally until decision... Repeat SA  in September. Aiming for IUI #1 November 2014.

    image

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  • LindseyNicholle84LindseyNicholle84 member
    I just made the appointment for the HSG. Got AF today. Starting the clomid in two days again. Thank you everyone for the support :D

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  • aves0708aves0708 member
    (( Hugs)) The IF world is so frustrating and disappointing. We also have an unexplained diagnosis, and I also experience a lot of spotting.  Because of the spotting my RE immediately wanted to do an SHG along with the HSG just to check everything out. You are smart for making that HSG appointment. I hope it's quick and painless, and that everything comes back good :)

    Me (29): Hashimoto's, CD3/7DPO bloodwork & ultrasound normal, HSG & SHG(x2) all clear
    DH (29): SA Perfect
    TTC Since Jan '13, First RE Appt Jan '14
    DX: Unspecified Ovarian Dysfunction, Long Cycles
    May '13 BFP, C/P 4w3d
    Apr '14:  50mg clomid + ovidrel + B2B IUI #1=BFP,  Natural M/C 6.5wks
    Aug '14: 50mg clomid + ovidrel + B2B IUI #2=BFN
    Oct '14: 100mg clomid + ovidrel + IUI#3 =BFN
    Nov 14: 100mg clomid + ovidrel + B2B IUI#4=slow response, bad lining, cancelled
    FU with RE, more bloodwork: Anticardiolipin +
    Dec 14: 5mg Letrozole+baby aspirin +ovidrel + B2B IUI#4.1=BFFN
    Jan '15: 5mg Letrozole +baby aspirin + ovidrel +B2B IUI #5= BFP!! 
    Beta #1 210  Beta #2 546


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