Trouble TTC

WWYD: 4 mature follicles w/ MFI ** BFP/chemical mentioned

Ladies.. I need any advice I can get. My head is spinning. I know it's a decision my DH and I have to make... but just curious what you all would do, especially if you are MFI.

So I had my CD10 u/s today. I now have 4 follicles that will be mature by Sunday at our IUI (triggering tomorrow night). If I triggered today, we wouldn't have any at 18. We are MFI w/ very low morph and low count. We had 9 mil motile post wash on first one & 6 mil motile post wash on second iui. The second IUI I had 2 folliclies and we did get a BFP but ended in chemical. I don't know what to do. My DH can't answer the phone at work so I'm flipping out at having 4 lol. We are okay w/ twins but I'm terrified of triplets now & I don't think we would want to do selective reduction. My DH does have sperm issues. So I'm at a crossroads. I really don't want to cancel, but I also want to be smart. Trying to weigh my probabilities and percentages is making me crazy. My DH has also been taking a Fertility Blend and mentioned he has noticed more sperm come out lately. Whether that's true or not, I have no idea. It's only been about 6 weeks.

Hmmm. Thanks for listening to my scattered brain right now lol. My RE wants us to decide what to do by tomorrow at our u/s.

****siggy warning****

Me 29/ DH 28
DH- MFI (low count, 2-3% morph)

IUI #1 January - Clomid, Ovidrel: BFN
IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
             Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
             6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
             7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
             7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

image

Pregnancy Ticker

Re: WWYD: 4 mature follicles w/ MFI ** BFP/chemical mentioned

  • Do it. Multiples are always a concern, but considering you're MFI, the chances of all 4 of those being fertilized & sticking is slim. Not impossible, but slim.
    Me: 38     DH: 36
    Married: July 21, 2013
    TTC#1 (between us): June/July 2013

    DX: MFI (low count and motility)
    Charting/OPK/CBFM July 2013-present
    1st RE Visit: January 2014
    Cycling: 
    March 2014- 75iu follistim + trigger + progesterone + IUI = BFN and OHSS
    (8 million post wash 47% motility, 18mm/17mm/16mm/16mm/14mm follies)
    April/May 2014- Benched due to cysts/enlarged ovaries
    June 2014- 50iu follistim + trigger + progesterone + IUI = BFP!!
    (10 million post wash 60% motility, 20mm/19mm follies)
    Beta 1- 85 Beta 2- 2,752 - EDD 2/27/2015


    Everyone welcome. Strength in numbers!


  • Loading the player...
  • @nariadreamingI have 2 at 16.5mm and 2 at 17.5mm... doing either 100-125 of follistim tonight and trigger tomorrow night for IUI Sunday.

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

  • Definitely with those sizes.... I was in a similar situation & I went for it. Purely because it sucks to cancel a cycle!
    Me: 38     DH: 36
    Married: July 21, 2013
    TTC#1 (between us): June/July 2013

    DX: MFI (low count and motility)
    Charting/OPK/CBFM July 2013-present
    1st RE Visit: January 2014
    Cycling: 
    March 2014- 75iu follistim + trigger + progesterone + IUI = BFN and OHSS
    (8 million post wash 47% motility, 18mm/17mm/16mm/16mm/14mm follies)
    April/May 2014- Benched due to cysts/enlarged ovaries
    June 2014- 50iu follistim + trigger + progesterone + IUI = BFP!!
    (10 million post wash 60% motility, 20mm/19mm follies)
    Beta 1- 85 Beta 2- 2,752 - EDD 2/27/2015


    Everyone welcome. Strength in numbers!


  • I don't have MFI, but I'm 39. I just triggered with 5 18-19mm and 3 more at 15mm. I'd def trigger with 4 but I'm not sure if you should trust my opinion.
    Fucking bump!!!!

  • Rumbera28 said:

    I'm on mobile so I can't see your siggy. Generally speaking, the older you are, the safer you'll be with a high number of follies.

    Each follie has a 20% chance in the BEST of circumstances,
    so I would go ahead with the IUI in your place. GL

    I love the way you worded this, because I can twist it in my head and say "well since I had 5 follies, I've got a 100% chance of getting KTFU this month" 

    :) Anything to keep my hope up, right? 

    My husband said the exact same thing the other day about our 5. :-)



    Fucking bump!!!!
  • I would follow the advice of PPs. Good luck!
    Love 2010 | Marriage 2011 | TTC #1 since 2012
    PCOS | Anovulatory | Metformin + Letrozole

  • Rumbera28 said:

    I'm on mobile so I can't see your siggy. Generally speaking, the older you are, the safer you'll be with a high number of follies.

    Each follie has a 20% chance in the BEST of circumstances,
    so I would go ahead with the IUI in your place. GL

    I love the way you worded this, because I can twist it in my head and say "well since I had 5 follies, I've got a 100% chance of getting KTFU this month" 

    :) Anything to keep my hope up, right? 

    Yes!!!
    Me: 38     DH: 36
    Married: July 21, 2013
    TTC#1 (between us): June/July 2013

    DX: MFI (low count and motility)
    Charting/OPK/CBFM July 2013-present
    1st RE Visit: January 2014
    Cycling: 
    March 2014- 75iu follistim + trigger + progesterone + IUI = BFN and OHSS
    (8 million post wash 47% motility, 18mm/17mm/16mm/16mm/14mm follies)
    April/May 2014- Benched due to cysts/enlarged ovaries
    June 2014- 50iu follistim + trigger + progesterone + IUI = BFP!!
    (10 million post wash 60% motility, 20mm/19mm follies)
    Beta 1- 85 Beta 2- 2,752 - EDD 2/27/2015


    Everyone welcome. Strength in numbers!


  • Thank you all for the responses. I am def. leaning toward going for it. But I'm going to have a deeper talk w/ my RE tomorrow at my last u/s. I'm hoping tomorrow he can tell me at least some statistics. You all have no idea how much I appreciate your support on here. <3

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

  • I would go for it. I was in a similar situation while on follistim with 4 possibly 5 mature follies. We had 12.5 million post wash and it was a BFN. With MFI, the chances of high order multiples are pretty low and my RE was comfortable with the decision to move forward.



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

    image




    Pregnancy Ticker




    March 15 Siggy Challenge: You had one job

    image
  • MissEm15MissEm15 member
    edited April 2014

    So my E2 number just came back and its 261.. Dr. Google says the number should be 200 per mature follicle. I mean I know mine aren't technically mature yet, but that doesn't sound good right?

    Edit to correct my E2#

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

  • MissEm15 said:

    So my E2 number just came back and its 247.. Dr. Google says the number should be 200 per mature follicle. I mean I know mine aren't technically mature yet, but that doesn't sound good right?

    My e2 never jumps up until the end. This cycle it was on day 11, e2 of 1173 but I had 19 measurable follicle and 6 in the 14-16 range. Day 8 I was only 384. Maybe in 2 days it may change a lot. I also read somewhere that everyone's body is different an e2 of 200 per mature follicle isn't an exact science it's more an estimate. Then again I could have dreamed this.

    Fucking bump!!!!
  • StacyLH24StacyLH24 member
    edited April 2014
    First, I would go for it. We just did an IUI with 4 size wise mature follies. I don't know what my e2 was for them because when I went on a Wednesday, only one was big enough. When I went back that Friday, all 4 were suddenly big enough. We use donor sperm, so we have no MFI. The chances of 3-4 fertilizing and implanting is very very slim. We decided previously that selective reduction was not an option for us. I want 3-4 follies because that means more chances that we will at least get one. We have decided to draw the line at 4, but that is certainly a very personal choice.

    Second, my follies always wait until the end to really mature and grow. It is very possible that your e2 will be much higher at your next check.

    Talk to your RE about your concerns for sure. When I had 6 mature follies back in January, he called me and we discussed the concerns. He supported my decision to cancel as he expressed that we could have high odds of three or more fertilizing and implanting.

    Good luck!

    Edit: I'm getting things mixed up...at my last scan before IUI, only one follie was size mature. The morning of my IUI there were 4 that were size mature. I had no blood work done before my IUI that morning, so I don't know if they were actually mature. Also, my RE says between 150-200 is considered mature.

    Me: 30  DW (aka C): 29

    Together since 2/15/11 ~ Legally married in NY on 9/29/12

    ***CP mentioned***

    We've been working on baby #1 since July 2013 using Open ID donor sperm.  8 IUI attempts with 5 actual IUIs and one chemical pregnancy.  We have one fresh IVF cycle under our belts as well as a FET.  I have endometriosis and a uterine septum that was corrected via surgery in November 2013. 

    11/14/14 -  Second HSG shows that tubes are still clear and ute is looking good. 

    12/6/14 - Started BCPs in prep for IVF #2

    12/22/14 - Saline u/s and endometrial scratch (All was clear and OUCH!)

    1/2/15 - Began stimming for IVF #2

     ****All Welcome!****

    We are Mommas to four fur babies - 3 dogs and 1 cat.

    image   

  • The user and all related content has been deleted.
  • When I had 4-5 follies measuring 15-17mm on CD10, my e2 was 1300 and I triggered the next day. I think everyone is different though and your e2 might climb tomorrow. Good luck!



    ********Siggy/Ticker Warning***********



    Me (35) no known issues DH (37) MFI. TTC 21 months (24 cycles)
    Dx MFI with low to normal count, low motility, morphology 3%
    HSG normal, ultrasound and labs on me all normal. 

    1 cycle of Clomid 50mg and TI, unmonitored by OBGYN= BFN
    1 cycle of Clomid 50mg and IUI, unmonitored by OBGYN= BFN
    Started seeing an RE!!
    2 more cycles of clomid 50mg (great response), with IUI and Pregnyl trigger (4.8-8 mil good ones after wash) = all BFN
    1 cycle of clomid 50mg (3-7) followed by Follistim 75iu (7-11) + IUI = BFN
    December 2013 DH saw urologist and is taking Anastrozole, CoQ10, and L-Carnitine
    IUI #5 natural cycle (needed a med break) = BFN
    IUI #6 Follistim 75iu (CD3-10) + Pregnyl (CD11) + IUI (final count after wash 300K) = BFN
    IUI #7 Follistim 75iu (CD3-9) + Pregnyl (CD11) + IUI on 2/20 (post wash count 12.5 million)= BFN
    IUI cancelled (DH OOT) Clomid 50mg (CD3-7) 1 follicle +(not well timed) TI = BFN
    IUI #8 and last one!! Clomid 100mg (CD3-7) +OPK before US + IUI 4/17 (post wash 8.5 mil)= BFN

    Pre-IVF testing complete! SHG great and measurements taken! Labs for infectious diseases completed, FSH (5.4), TSH (1.6), Prolactin (11), AMH (2.6), Estradiol (40).

    Started BCP 5/29 and Lupron 6/11 prep for IVF #1! Started follistim 225u/day on 6/28. Monitoring on 7/2 >15 follicles measuring 11-14, E2 758. Monitoring on 7/5 all ready to go!! Great follicle sizes and lining is at 9. Tigger 7/5, ER 7/7 16R 9M 3F. Stimmed too fast in just 7 days. 7/10 3dt of 2 8-cell grade 2 & 4. 7/14 P4 >60.
    Holy crap BFP!!!
    Beta #1 (14dpo) 7/21 112 Beta #2 (16dpo) 7/23 286 a Beta #3 (18dpo) 7/25 761 Beta #4 (21dpo) 2631!!! Hold on tight little embies!!
      First Ultrasound 8/7- 1 perfect little bean with a beating heart 117bpm!! EDD 3/30.
    Second ultrasound 9/2 Little bean measuring a few days ahead with a heart rate of 161!



    PAIF/SAIF/All Welcome!

    image




    Pregnancy Ticker




    March 15 Siggy Challenge: You had one job

    image
  • My RE just called and said my 261 E2 was normal (not 247, I remembered wrong). Anyway, I trust him. I just wish he would explain better, but I know he knows what he's doing. He said I don't even need estogen patches this time, which is different.  I'm doing another shot of Follistim tonight with trigger tomorrow and IUI Sunday. I'm sure the Follistim will help my lining and E2 as well.

    Thanks everyone for the info! I don't feel like my number is that terrible anymore... but here's hoping tomorrow is better! Is it sad to be ready for the 2WW lol. So stressfull!

     

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

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