New here! Feeling anxious.

AnnaClaire256 · April 2014

I'm new here so I thought I'd give y'all a little back story. I'm 28, DH is 37. He has two teenage boys from a previous marriage but we have been TTC together for 2.5 years (16 months of medicated cycles). I started out on 50mg of clomid and worked all the way up to 150mg with some success. I have had several cycles where I developed nicely and received a trigger shot. One resulted in a chemical pregnancy, the others just BFN. My last cycle with clomid 150mg was a bust. No maturing follicles on CD14. Instead of waiting a month he immediately restarted my cycle and switched me to femara 5mg. I went in 12 days later and was thrilled to see three large follicles! I took the trigger shot that day and felt really good about things. 5 days later, AF came. The dr tested my progesterone and said it looks like I had a late ovulation with the CLOMID!? All so strange. He started me over on femara and the cycle was a bust. Follicles that never grew past 11mm. Our last resort before switching to injectables and IUI was one last round of clomid but 200mg this time. CD 10 I had 5 follicles (15mm, 16mm, 18mm, 22mm, 24mm)! I triggered Wednesday afternoon and my dr said I should've ovulated Friday morning early. Of course, I'm nervous and skeptical...so I took an at home OPK. I got very negative tests until Saturday morning when I THINK I had a surge. It's just so hard to tell with those tests and sometimes I think I see what I want to see. I want to believe that we have got a shot this month...but I'm just so anxious. Is it possible to have mature follies, trigger and then not ovulate? Any thoughts or good vibes are sooo appreciated!!! I'm so glad boards like this exist.

KT416 · April 2014

I don't have any experience with your exact situation but I wanted to send good vibes your way! Welcome!

Pintobean39 · April 2014

OPK's don't really work when you do a trigger shot. Trigger shots are HCG which will turn an HPT and an opk positive so I wouldn't put much thought in the positive opk you got after the trigger. I'm not sure about triggering and not actually ovulating, I think you just have to have faith in your RE that he/she knows what they are doing.

Welcome and Good luck!

Just curious did you take clomid for 16 months?

AnnaClaire256 · April 2014

Thanks ladies!
I've done 16 cycles all together. First with clomid, then femara, now back to clomid. I called and asked about the negative OPKs after the trigger and my dr said the same thing you did....that the trigger should've automatically given a positive. I guess that's why I worried. Hopefully they know. That's why we pay them the big bucks, right?

Pintobean39 · April 2014

I thought you could only do 6 cycles of clomid in a lifetime? Without causing long term problems.

AnnaClaire256 · April 2014

RE now. But only just recently. She's the one who suggested going back to clomid since I had had "success" there before. And yes, triggered with 5 follicles but they said they only thought two would ovulate. Not sure why. I do have PCOS so there's always the fear that they are cysts

erollis · April 2014

Welcome! Fingers crossed for you getting pregnant soon.

I haven't started on Clomid yet because we aren't done doing all our tests. My Doctor refuses to do more then 6 cycles of it. They feel it's a waste (and not good medically) to start before you know what's wrong. You may need to find a new doctor.

sweetsurrender9 · April 2014

Welcome. I'm sorry that you've got to be here, but you've found a great group for support.

I echo the idea that you might want to seek a second opinion; that many cycles on Clomid is kind of unheard of.

AnnaClaire256 · April 2014

Oh my!? I did 6 cycles on 50mg alone! We stuck with that because I responded well. When I stopped responding there they bumped me to 100mg. Same thing to 150mg. Then technically 3 cycles with femara. Now back to the clomid. This was by FAR the most response I've had.

AnnaClaire256 · April 2014

I guess I never knew that it was abnormal. I have started seeing the RE but she's been overseeing my case for months.

Lillovebug79 · April 2014

Pintobean39 said:

I thought you could only do 6 cycles of clomid in a lifetime? Without causing long term problems.

Yo can actually do more clomid cycles as long as you are responding and being monitored. My RE said that most people get a benefit from it if they are going to within 6 cycles but it doesn't hurt anything to do more. Since our issue is MFI and I've responded well to clomid,she would prefer to keep using it as opposed to trying Femara. I have noticed that my body seems to be building up a resistance to it though and my dose had to be increased this cycle. Luckily, this is my last cycle before IVF!

AnnaClaire256 · April 2014

Hoping4LO said:
Welcome! 16 cycles seems like a lot.

Thanks. It seems like a lot to me, too. Trust me! Hoping for the best this cycle...ready to move on to injectables if this doesn't work.

Pintobean39 · April 2014

AnnaClaire256 said:
RE now. But only just recently. She's the one who suggested going back to clomid since I had had "success" there before. And yes, triggered with 5 follicles but they said they only thought two would ovulate. Not sure why. I do have PCOS so there's always the fear that they are cysts

Do you know what your E2 level was at time of trigger?

I'm trying to figure out why they would say only 2. I'd think all 5 have a chance but I'm no Dr. I thought I read somewhere anything above 12mm has a chance, but I could have dreamed that. Does anyone know?

I've been googling all day about E2 levels and follicle count. My RE will let me trigger with 5-6 but I have egg quality issues because of my age.

AnnaClaire256 · April 2014

No clue. They haven't ever tested my levels. My dr asked if we were prepared for a multiple pregnancy and then said, "Highly unlikely it would be more than twins. I only think two will ovulate." I should've asked more questions...maybe since I triggered right away and two were so large?

CaitlinAnn24 · April 2014

Welcome! I hope you find this board as helpful as I do

I do have to echo the PPers, though...that sounds like A LOT of clomid!

AnnaClaire256 · April 2014

CaitlinAnn24 said:
Welcome! I hope you find this board as helpful as I do I do have to echo the PPers, though...that sounds like A LOT of clomid!

Thanks! I'm hoping for the best but ready to move forward

BunnyBerry · April 2014

Welcome, sounds like you've been through a long struggle already. I hope this month is it for you!

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