Trouble TTC

Question RE: IUI

For those who have been through IUI, I will be giving myself the HCG shot tonight.  I was lucky to have no bothersome side effects really from the Clomid ...I hope I will be as lucky with the HCG shot!  

My question is this.  My IUI will be Saturday at 10:50am.  The Nurse Practitioner instructed me to take the HCG shot tonight at 10pm.  Doesn't ovulation typically happen 24-36 hrs after the HCG shot?  And if that is the case, wouldn't the insemination be possibly "too late" as it will be a little over 36 hours (36 hrs and 50 min to be exact).  I want to trust my provider but I want to make sure I understand the reasoning too.  What do you think, ladies?  
**Formerly EastBayBride508**

Me 34   Him 33

Me - Left salpingo-oophorectomy at 19 due to large cyst/torsion  and 2 large uterine fibroids found at age 30
Him - Borderline low sperm count (correcting through Fertility Blend supplement)

Married 8/20/2011
TTC #1 since Jan 2013
First appointment with RE 10/2013.  
April 2014 - Clomid 100mg CD3-7.  HCG shot CD10 IUI #1 done on 4/12/14 (CD12) ....BFN
May 2014 - Break cycle to repeat saline sonogram and re-group.  Travel to Kauai 5/7-5/12 (Yay!!)
June 2014 - Clomid 150mg CD4-8.  HCG shot CD14.  IUI#2 done on 6/9 and 6/10 (CD15-16) w/ Prometrium suppositories during TWW .... BFN
July 2014 - Clomid 150mg CD3-7.  Ultrasound CD12 - 4 mature follies! HCG trigger shot CD12 AM.  IUI#3 on CD13 w/ Prometrium suppositories during TWW ....BFN
July 2014 - Repeat ultrasound done to measure size of fibroid - 8x9cm (the size of a grapefruit!) Surgery referral made.
August 2014 - MRI done which revealed 2 fibroids: a 13x15cm fibroid as well as an 8x7cm one.  Super freak out mode over surgery plan.  OB-GYN/surgeon said surgery would most likely have to be a laparotomy (open abdominal surgery)
August 2014 - After a 2nd opinion, plan to take Lupron x 2 months to shrink fibroids then laparoscopic/robotic myomectomy.  Surgery date is set for Nov 21st!  
November 2014 - Robotic myomectomy done (2 large fibroids removed, mild endo found).  Benched x 3 months

PAIF/SAIF welcome

Re: Question RE: IUI

  • Interesting, thanks for your response NariaDreaming  :)  I think I will do as your RE told you and do 36 hrs on the dot.  That would be about 11pm tonight (just a 1 hour difference from when she told me ....not sure how much of a difference that will make).  My RE told me that we should abstain from sex until after the insemination though!  It's interesting how recommendations can be so different from 1 RE to another.  
    **Formerly EastBayBride508**

    Me 34   Him 33

    Me - Left salpingo-oophorectomy at 19 due to large cyst/torsion  and 2 large uterine fibroids found at age 30
    Him - Borderline low sperm count (correcting through Fertility Blend supplement)

    Married 8/20/2011
    TTC #1 since Jan 2013
    First appointment with RE 10/2013.  
    April 2014 - Clomid 100mg CD3-7.  HCG shot CD10 IUI #1 done on 4/12/14 (CD12) ....BFN
    May 2014 - Break cycle to repeat saline sonogram and re-group.  Travel to Kauai 5/7-5/12 (Yay!!)
    June 2014 - Clomid 150mg CD4-8.  HCG shot CD14.  IUI#2 done on 6/9 and 6/10 (CD15-16) w/ Prometrium suppositories during TWW .... BFN
    July 2014 - Clomid 150mg CD3-7.  Ultrasound CD12 - 4 mature follies! HCG trigger shot CD12 AM.  IUI#3 on CD13 w/ Prometrium suppositories during TWW ....BFN
    July 2014 - Repeat ultrasound done to measure size of fibroid - 8x9cm (the size of a grapefruit!) Surgery referral made.
    August 2014 - MRI done which revealed 2 fibroids: a 13x15cm fibroid as well as an 8x7cm one.  Super freak out mode over surgery plan.  OB-GYN/surgeon said surgery would most likely have to be a laparotomy (open abdominal surgery)
    August 2014 - After a 2nd opinion, plan to take Lupron x 2 months to shrink fibroids then laparoscopic/robotic myomectomy.  Surgery date is set for Nov 21st!  
    November 2014 - Robotic myomectomy done (2 large fibroids removed, mild endo found).  Benched x 3 months

    PAIF/SAIF welcome
  • Loading the player...
  • I tried to trigger as close to 36 hours ahead of the IUI as possible.  I set an alarm for midnight, woke up and triggered and went back to bed. 
    Married on October 20, 2012.  Began trying in January 2013.
    RE appointment & testing December 2013 - February 2014= Unexplained IF, possible endometriosis
    IUI#1- March 22 (100mg clomid, 75 mg of Bravelle, Ovidrel trigger) = BFP!!!



  • Mine says to trigger between 6-8 and they do the IUI usually around 10 am two days later so we're close to 40 hours (well I usually do at 8 so 38 hours) but I figure if that's what usually works for them that's what I'll do.

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

    image    image
  • **chemical mentioned

    My Re says 36 hours exactly before my IUI appointment. They usually are about 20 minutes late by the time I do my actual IUI. We BD the day of the trigger (or night before) and the night of the IUI. We had a bfp last month (ended in chemical) so I trust my RE's recs.

    ****siggy warning****

    Me 29/ DH 28
    DH- MFI (low count, 2-3% morph)

    IUI #1 January - Clomid, Ovidrel: BFN
    IUI #2 February - Letrozole, Follistim, Ovidrel: BFP 1st beta-25, 2nd beta-56, 3rd beta-45, miscarriage
    IUI #3 April - CD3 U/S 4-10. Letrozole, Follistim, Ovidrel CD11 - Cancelled.. TI w/5 follicles-BFN
    IUI #3.1 May - CD3 U/S 5-6, Follistim start 5-11 thru 5-17, u/s 5-18 3 mature w/ a close 4th, IUI 5-20 - BFP!
                 Beta #1 12dpo - 164 & progesterone - 89!, Beta #2 16 dpo - 1189, 5w3d - u/s shows TWINS!
                 6/19- u/s showed heartbeats! Baby A 111 & Baby B 118, both measuring 6w1d
                 7/3- Baby A hb 170, Baby B hb 166 - both measuring perfect.
                 7/18 - Baby A 165, Baby B 171 - both measuring right on track & moving all around!

    image

    Pregnancy Ticker

  • My instructions were to trigger Monday @10pm and the IUI was scheduled by Wednesday morning at 7:30am. We ended up doing it closer to 9am after prepping the sperm and according to U/S follies were still there so we didn't miss O. Afterwards I was seriously cramping for a good 24h. Good luck!
    *Losses mentioned*
    Me: 34 DH:32
    TTC #1 since Dec 2011
    HSG = tubes clear, bicornuate or septate ute; MRI= severe arcuate uterus no septum seen 
    SA #1 low count, low morph;  SA#2 4% Morph, count OK  SA#3 july 2014= NORMAL!!!
    9/2013  IUI#1 w/Clomid 100mg = over response; cycle converted to cryoocyte IVF
    IVF #1: 9/15 ER= 9 mature eggs, all eggs made it thru vitrification
    10/23 ICSI 6 fertilized; 10/28 5dt of two morulas. Hold on to me babies, stick, stick, stick!!
    11/6 BFP EDD 7/14/14 Beta #1= 18; 11/9 Beta #2= 44.8; 11/12 Beta #3= 7 = Early loss @4w6d. No frosties
    Feb 2014 Hysterscopy = no septum seen ute all clear in the inside
     IUI #1.1 4/2/14 Beta on 4/16 BFN
    Thinking about IUI #2  RE advised to try 3?????
    Natural cycle surprise BFP 8/3/14 EDD 4/11/15  beta#1(8/5/14)=35 Beta#2(8/8/14)=22  CP/Early loss@5w
    PAIF/SAIF Welcome
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