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Third-Party Reproduction
Mrs.McIrish
member
Finally A Good First Beta!!!
Mrs.McIrish
member
I'm shocked to say that my St. Patrick's Day Clover has made a liar of me. First beta is 197!!!!! I never thought this would happen as the embryo was a day 6 (FET) and not the best...I even drank 2 glasses of wine last Friday night at dinner- that's how sure I was that it was a bust.. I'm crying tears of joy and hoping this one will stick around. Repeat beta on Monday.
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
This discussion has been closed.
Re: Finally A Good First Beta!!!
We're queer. I'm 33, have severe stage 4 endo, and had both fallopian tubes removed. My love ("Manada" on the boards, 32) was diagnosed with diminished ovarian reserve. We did Partner IVF (my eggs, her uterus). We lost our twins Tavin and Casey at 21 weeks gestation.
Our IUIs
with @Manada: IUI# 1-7 (December 2012- September 2013) all BFN. Tried natural, femara, clomid, puregon/follistim, clomid and menopur combo, both the ovidrel and HCG triggers.
Our IVFs:
IVF #1 my eggs November/December 2013: Cancelled IVF due to poor response
IVF #2 my eggs/Manada's uterus January/February 2014
BCPs and lupron overlap Stimmed: 1/22-2/2: Bravelle and Menopur (dosage ranged from B300 and M150 to B375 and M150 to B300 and M225)
2/4 retrieved 10 eggs. Endo was much worse than expected. Only 3 eggs fertilized; February 7 transferred two day 3 embryos, froze one. All great condition.
BFP eve of 6dp3dt; Beta 1 (11dp3dt): 110; Beta 2 (13dp3dt): 175; Beta 3 (15dp3dt): 348; Beta 4 (19dp3dt): 2222; Beta 5 (21dp3dt): 4255
1st ultrasound (3/6 6w 1d): TWINS!!!! Twin A measuring 6w1d with a heartbeat of 118bpm. Twin B measuring 6w0d with a heartbeat of 113bpm.
***July 18, 2014 we lost our beautiful babies at 21 weeks gestation. They were born too early. Tavin Sara T. and Casey Elizabeth T. are beautiful and precious and we will love them and miss them forever.***
FET #1 December 2014
That is a wonderful first beta!!! I have everything crossed that this little clover (or clovers) will stick around for the next 9 months!!!
Of course, also sending doubling vibes your way as well!!
Me: AMA, DOR, undetectable AMH, carrier of SMA, MTHFR homozygous C677T, high cytokines, low IGg B cells, Factor XIII V34l mutation, High Anti-Phosphatidylethanolmine, borderline hypothyroid and mildly insulin resistant.
MH: No known issues, aside from MTHFR.
Recommendations from RI: LIT, Humira, IVIG, Lovenox, Baby Aspirin, Folic Acid, Low-dose synthroid and Metformin.
Currently taking: Pre-Natal vitamins, Foltanx, Low-dose synthroid and Metformin.
When cycling also taking: Baby Aspirin, Lovenox, Humira and IVIG.
TTC since 7/11/09..with medical intervention starting in 2010, including 4 failed IVF's and 6 failed IUI's...only "success" was a chemical pregnancy in 11/2012 (credited to use of DE).
FET #1 (11th cycle) on 8/23/13 = BFN.
FET #2 (12th cycle) Transfer of last two (day 6) donor egg blasts on 1/22/14 = BFP, EDD = 10/10/14 (please stick little BOY!)
My favorite breed:
***PAIF/SAIF always welcome***
TTC since April 2010
BFP #1 – March 2011, missed m/c April 2011
BFP #2 – October 2011, m/c November 2011
Surprise BFP #3 – December 2011, diagnosed as cornual, terminated January 2012
BFP #4 – June 2012, m/c July 2012
Diagnosed with bicornuate ute and MTHR gene mutation
BFP #5 – October 2012, missed m/c November 2012
BFP #6 – January 2013, m/c March 2013
No longer TTC. Diagnosis: Hostile ute. Heartbroken and bitter. Pursuing surrogacy.
June 2013 - Carrier found! Could this really happen?!
~All AL always welcome~
************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI
12/2/11 - IUI #1- BFN
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
My ovaries are just for decoration
12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts.
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.
6/5/13 - Adopted four new embryos that had been frozen for seven years!
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d.
11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522 Beta #2 @ 16dp6dt - 1373
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!
Snowflake baby is a girl!
Our beautiful Snowflake girl arrived on July 22, 2014!
My embryo adoption blog: Wishing on a Snowflake
Sept '11-April '13 ~ Testing, failed multiple MFI treatments, saving & TONS of praying
January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN
February 2014 ~ On to donor embyros ~ 5 blasts!!!
March 2014 ~ FET #1 ~ Transferred 2 blasts ~ BFN
July 2014 ~ Kliman's mock cycle with endometrial function test
Sample too small for EFT, HE slide showed immature cells
New protocol planned, saving for another biopsy for EFT
January 2015 ~ Considering adoption options
April 2015 ~ Privately arranged adoption of planned pregnancy
DD#1 ~ Lillyana Violet Marie born 6/15/16, Finalized adoption 12/20/16
July 13, 2018 ~ BFP....WTF?!?!
7/16 Beta #1 ~ 466...7/18 Beta #2 ~ 1,077...7/23 Beta #3 ~ 5,291
7/23 US #1 ~ 1 gestational sac seen and yolk sac
7/30 US #2 and 1st OB appt ~ 1 perfectly round gestational sac, 1 perfect yolk sac and 1 teeny tiny heart beat seen!!!
Me (43) and J (45) - same sex couple. And we don't feel 40+!
June'12 - First RE Visit
Sept. '12 - Tubes removed
Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
Loss due to umbilical cord clot...baby was perfect.
Jul '13 - FET#1 - c/p
Sept. '13 - FET#2 - BFN
Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
Dec' 26, 2013 - hb!!
EDD 8/20/14 with a baby girl!
Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
We live in Seattle and used SRM for our donor egg IVF cycle
ME:46 MH:44 DE IVF 2014
Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive. Waiting for another donor. Donor picked!! (1/18/14)
DE IVF #1 (4/26) BFN DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!
12/2011: Finished chemo
5/2013: Cleared for DE IVF
11/13: DEgg IVF#1
8/5/14: Grace was born!
Praying unceasingly for a miracle. ALL welcome!
April 2013 DE IVF= BFN
September 2013 DE IVF (Fingers Crossed) = BFFFN! again...
October 2013 FET of our last 2 = Beta Hellzz for 6-7 Weeks. M/C
TTC #1 since June 2012
Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
DH (29) - MFI low count and morphology
September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN
Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
Results: Cancelled after 11 days of stims due to low response and E2 levels
Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
Results: 1 retrieved / 0 mature = Cancelled after ER
Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
TTC Since 12/2008; DH: 32, Azoospermia me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due
to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder
High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder
IVF w/ ICSI #1 2/2011 IVF w/ ICSI #2 5/2011 IVF w/ ICSI #3 12/2012 *New RE* IVF w/ ICSI #4 5/2013
IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
IUI #1 12/23- BFN IUI #2 Cancelled (ovulated during AF) Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12, Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week- Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x, Femera & Menopur
IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766 EDD: 3/23/2015
DOR and AMA
2/12-5/12: 4 IUI cycles = all BFN;
7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
Lupus anticoagulant initially high, then found to be normal on hematology consult;
Follow up testing in September all clear;
Started synthroid for "high normal" TSH;
FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
12/12- Officially an OB patient!
Level 2 ultrasound at 20 weeks shows vasa previa and VCI
Referral to MFM and mandatory c section for delivery
Beautiful baby girl born at 34 weeks
Finally home after 15 day NICU stay!
Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
FET #3, early July 2014; beta 7/14, BFN
DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
FET #4- December 2014, yet another BFN
Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)
Added baby aspirin, prednisone, supplements, Metanx, and intralipids
Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN
Likely OAD- NBC
Diagnosed with Ovarian Cancer January 1996
One small cancerous cyst (left ovary) removed Jan '96, chemotherapy Jan - July '96
Three more cancerous cysts found July 1996 (left ovary), ovary removed July '96, chemotherapy July '96 - Feb '97
February 1997 given all clear! Told of suspected infertility
Tove Ikarus born July 2010, given guardianship September 2010
April 2014 infertility confirmed
IVF with sister's eggs July 2014
(Hopeful) adoption of Tove July 2015
@LaireAndLia is my sister's partner, @DragonsLaire is my sister