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Can anyone that was finally successful give me some encouragement/hope? ALL BFN IVF ATTEMPTS

SKLHSKLH member
in Success after IF

I'm pretty new to The Bump so I hope it's okay for me to post this question here. I could REALLY use some encouragment:

 

Has anyone endured several BFN (literally NO implantation) IVF cycles and went on to a successful preganacy via IVF? We have done 1 failed IVF and 2 FET. I am only 28, husband 30. We produce a lot of embryos and none seem to stick around. We recently switched RE's... did a new cycle with the BEST results yet. We biopsied all the blasts and they are being tested. My new RE seems to think it's just a matter of the perfect embryo as all of my tests come back normal (including immune/RPL). Anyone have a encouraging stoy for me that you eventually found the "perfect" embryo that stuck after several rounds of total BFN - one stark white preg test- no implantation at all? I just want to know I CAN physically get pregnant. It's so discouraging to have all the right ingredients but never have any of them stay and grow... Encouragement needed!<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

Me (28) DH (32)  Endometriosis                                                                                   IVF  #1 (1/2013) - 17 Retrieved, 16 Mature, 14 Fertilized- 2 transferred- BFN
FET #1 (7/2013) - 2 embryos - BFN
FET #2 (9/2013) - 2 emrbyos - BFN
New RE. Fresh Start
IVF  #2 (2/2014) - 25 Retrieved, 19 Mature, 16 Fertilized, 9 blasts.
                             CGH Testing: 6 Normal
FET #3 (4/2014) -1 embryo -  BFP! Beta#1: 35 Beta #2: 16 :(
FET #4 (5/2014) -1 embryo -  BFP! Beta#1: 321!!! Beta #2: 727.9! 6/5/2014 Heartbeat! 144bpm It's a girl! Due January!
   

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Re: Can anyone that was finally successful give me some encouragement/hope? ALL BFN IVF ATTEMPTS

  • STL34STL34 member
    My only pregnancy (previously no implantation at all with betas always at 1 or less) came on IVF #3.

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • Ruthie04Ruthie04 member
    I'm so sorry about your failed cycles. A failed IVF is extraordinarily hard to make sense of. My first cycle was canceled for a dominant follicle and the follow up cycle yielded a good egg/embryo count, but awful quality (with the exception of 1 "perfect" blast- BFN) on day 5. The second full cycle brought us 16 embryos with about 8 blasts, but only two were even mediocre enough to transfer. Those blasts became my twins. We never met the quality standards for my clinic and do not have any frozen embryos. My RE thinks we have embryo quality issues that result in complications around implantation. I had a previous pregnancy, but it was an early miscarriage. We added in assisted hatching and pre/post transfer acu and I can't help but wonder if that helped. I was 29 at the time of my ERs.

    GL to you and your husband.
    TTC in 2009, Dx: Unexplained IF
    Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
    12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
    Our perfect baby boys were born at 36w1d!! 








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  • luvbostonluvboston member
    what kind of immune testing have you had?
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story


    image
    image


    Lilypie - (ugiy)


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  • CarrieB.CarrieB. member
    Have you done the Etrigrity test? Not sure on spelling, but it tests implantation.
    IVF, acupuncture, meditation and a miracle. 

    image

     Our sweet Valentine's Day FET.

    image

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  • LittleLady77LittleLady77 member
    I have a different problem that required donor eggs but I just wanted to hop on and say I'm so sorry you're going through this. There is always hope. A friend of mine finally had success on her 9th transfer (combo of IVFs and FETs).

    imageimageimage
    Lilypie First Birthday tickers
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  • Julie21613Julie21613 member
    My successful pregnancy came on my 5th fresh IVF.  Never had any frosties.  Out of the 5, I did get pregnant on the 1st & 3rd cycles too.  First one ended in a m/c at 6 weeks 2nd was a missed m/c.  Seems I get pregnant every other cycle.  Info in my siggy...
    Me 35, DH 36
    TTC summer 2008
    Diagnose me. DOR, DH perfect
    IUI # 1 6/2010, BFN
    IUI # 2 8/2010, BFN
    IVF # 1 10/2010 Canceled poor response
    IVF 1.2 12/2010 BFP! mc 6 weeks 2 days
    Mental health break for 10 months
    IVF # 2 10/2011 BFN
    IVF # 3 5/2012 BFP! 10 eggs retrieved (best ever)
    7 fertilized transferred 3
    Beta #1 14dpo - 72, Beta #2 17dpo 145 Beta 3 20dpo 521
    First u/s June 15 saw HB 126 bpm missed m/c 7/5/12 10 weeks D&C 7/6/12
    IVF#4 ER 9/30 ET 10/3 Beta 10/16 BFFN. IVF #5 final with o/e. ER 1/21 only 1 retrieved, hoping my lonestar is the one. Beta #1 2/6/13 = 209.... please let this be it! Keep growing lonestar! Beta #2 2/8/13 - 586! , Beta #3 2/10/13 = 1898. First u/s perfect little heart beat at 116 bpm. Measure 6 weeks 1 day. EDD 10/14/13
    3/4/13 measuring right on track beautiful heartbeat 171 bpm, graduated from RE to OB... bittersweet.
    PAIF/SAIF always welcome! Its a girl! 

    Maggie Grace is here!  10/5/13... 8lbs 6 ounces of pure joy!

    TTC#2  No birth control since DD was born.  Getting ready to jump back in the saddle.  Weaning this month. RE
    appt scheduled 5/8.   Here we go again!

    IFV# 6.  10/27  6 retrieved 4 mature 3 fertilized.  2 made it to 3dt 10/30. 1"very pretty 8 cell" and 1 6 cell.  Beta
    11/13.   Please stick embies!!!!  We love you so much already! 11/12/14  POAS, BFP... beta tomorrow!
    11/13 beta #1  924!!!  2nd bet 11/15 1906, one more on 11/17 3rd & final beta 3430.  First u/s 12/5, 7w4d, 2 heartbeats,
    both measuring right on track....2nd u/s... all is well... both beans measuring right on track... released from RE... first
    appointment with MFM 1/5.  Looks like this is really happening!

    image




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