Infertility

IVF with high fsh and low estrogen

Hi I'm 30 years old with diminished ovarian reserve0.3 with slightly high fsh and low estrogen. I have used this blog for other questions and have gotten helpful responses from women that have or going through the same thing. This question is for any women that have had up and down fsh and estrogen levels and have had success with IVF with their own eggs?... I'm going to see my doctor on Tuesday to discuss our option of IVF. I did an iui last month but was unsuccessful. I was on bravelle and had 3 out of 9 follicles were growing but only one that was to the fullest number when I did the trigger shot. I also wanted to know what are some questions I should ask the doctor that might help us. Any stories or responses would be awesome thank you!

Re: IVF with high fsh and low estrogen

  • Hi, I'm sorry you find yourself here. Most of the ladies on this board, including myself, are doing IVF and are TTC #1. You should look at PAIF (Pregnant after IF) and SAIF (Success after IF) if you are looking for success stories. If you're looking for a support system of other women going through the same process as you, then you found the right board! Good luck at your appointment on Tuesday!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
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  • Hey @Erinmae23 - Just wondering, did you have your Vitamin D levels checked? Some studies are showing a correlation between Vit D and AMH. I know I was originally deficient in Vit D and once I got mine up my AMH went up 0.3 ... When you have low AMH every little rise counts. Good luck!
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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  • I did not find success with my own eggs and we moved on to a donor.  That doesn't mean there isn't a good egg still in there but at my age(36 almost 37), previous losses etc.. We just had to move on after 2 years and an obscene amount of money spent.  We knew we could only afford one more IVF and we wanted the very best odds.  It is a very personal decision and it took us a LONG time with a lot of failures along the way to be ok with it. It was hard. If I were younger ( and had more money) I would have at least tried another time or two. Just wasn't in the cards for us.



    ***siggy/ticker warning***

    Me:36 DH:38 TTC#1 since 4/2012
    Me DX: Hashimotos,Hypothyroid, DOR, MTHFR,  DH: normal

     IUI #1-#4 BFNs and a few cancelled cycles in the mix.
    - poor responder
    ***Suprise BFP on 6/13/13. Natural MC @6wks 3days
    IVF#1 and 2- Cancelled due to no response on max stimms
    FET 5/20- BFP
    1st Beta- 641
    2nd beta- 2166
    Sono- TWINS!!!!
    Two Boys! Born January 2015 @36 weeks.  Healthy and no NICU!  So blessed!



    image 

  • I had higher FSH and low AMH and got pregnant on my third IVF cycle.  I never had a great response.  But, apparently it was good enough. I was 33 years old for my successful cycle.

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

  • I am very interested in your journey. I too have slightly elevated FSH and low estrogen. My FSH has been anywhere from 7.9 (lowest) to 10.3 (highest). I have not met a lot of women who have this issue. My progress has been so-so. You can check out my signature for my details. I seem to have an egg maturity issue. Best of luck to you.

    Me & DH (33), 3 Furbabies, TTC since October 2011
    Day 3 #’s (Dec 2012) FSH 9, AMH .77, LH 2.4, E2 31, AFC 9 

    DX: Me-DOR + No Tubes, DH-Fine

    Ectopic 2007; lost tube/2nd tube removed Dec 2011 (hydro)

    April 2012=IVF#1- EPP Antag+ICSI, 2R,0F (BFN), Now dx’d with DOR.

    June-July 2012=IVF#2- MDL+ICSI&AH, 8R,4M,3F (BFP 9dp3dt) Beta#1 at 11dp3dt=36, Beta#2 at 15dp3dt=156, Beta#3 at 19dp3dt=671, dx'd with SCH, no growth-m/c at 7wks/Lap Dec 2012 to remove small fibroid.

    Feb 2013=IVF#3-MDL, 2/1=baseline, started 10 units mdl, AFC-7, 2/3 start gonal f, self cxld cycle b/c of low e2.

    April 2013=IVF#3.5-(with new RE)AG/ANT Conv + ICSI. 4/10-4/23 bcp's, 4/20-4/27 lupron, 4/28-ganirelix until end of stimming, 5/2-600 gonal f, 5/4-add 1/2 vial menopur, 5/13-ER (9R,1M,1F), 5/17-ET, 1 beautiful 8 cell (please be my sticky baby!!!!) 5/28-BFFN.

    Oct 2013=IVF#4-LLP+ICSI &AH, 10/14 (6R, 2M, 2F), 10/17-ET, 1 seven cell & a six cell, BFP at 9dp3dt, 1st beta=56, 2nd beta=52, CP.

    Jan 2014=IVF #5-LLP, Cxld after 6 days of stims due to fast response and lead follicle. 

    March 2014=IVF 5.5-LLP, Lupron 3/10, BL 3/18, 11 days of stims, Trigger 3/29, ER 3/31. 7R, 2M, 2F. ET 4/3. Txfd one 5 cell & one 9 cell. BFP on hpt from 7dp3dt & on. Praise be to God. Beta #1 at 11dp3dt=106, #2 at 13dp3dt=239. First u/s 4/28, measuring on track & heartbeat seen. 5/5-2nd u/s, measuring on track with strong heartbeat. 5/12- 3rd u/s & released from RE. Grow baby grow, we love you! Baby G&T is a BOY! Born 12/2014 via c/s! 8lbs, 8oz & 21 inches.


     *******Ticker Warning**********

     
    Lilypie First Birthday tickers

     
    "God's Delay is not God's Denial"
  • **** Loss Mentioned 

    My fsh is borderline high (highest was 10.1 but normally around 9) and my E2 is around 25 at baseline. My AFC and AMH are pretty high, though. I did get pregnant with an unmedicated IUI last march but that ended in a Blighted Ovum. I did my first IVF in Jan - 22 eggs retrieved but only 8 were mature so I think my numbers have to do with an maturity issue. 

    ******Siggy Warning**************

    Me 29 - no known issues ( Highest FSH 10.1??) 
    DH- 36 - quite the perfect man!
    TTC since 1/2011
    IUI #1 March 2012 
    BETA #1  BFP
    B/O at 6 weeks D&C @ 10 weeks 
    IUI #2-7 (2012)= BFN
    IVF  Jan 14 - Follistim, Ganirelix
    22R, 8M, 8F
    ET  (1-14-14) - 1 Grade A 8 cell = BFN
    FET (2-18-14)  1 grade A 12 cell and one early morula!
    BETA #1 (3-3-14) =1,389  p4 17.4
    BETA #2  (3-5-14) = 4,553 u/s showed one small g sac
    U/S #2      (3-17-14) Shows two little beans with heartbeats!!! TWINS!! 
                                       Heartbeats were 119 & 120 beans measured (6 weeks 1 day) (6 weeks 2 days)
    found out at 20 weeks that baby B went to heaven
    11/12/14 Baby girl arrived :)
    FET (1-24-16) Grade A early morula 
    BETA #1 300 p4. 11.1 
    BETA#2 1300
    u/s d 1 tiny babe :)
    10/7/16 another sweet baby girl
    4/18 SURPRISE + HPT 
    Beta #1 6 weeks 16,202 p4. 13.2




  • I'm 27 and also have high fsh. It's really overwhelming to hear that kind of news. I first found out my fsh was abnormally elevated at 25. Wasn't what I expected to hear! I've heard all kinds of things about supplements and diet changes. I've also heard that there really isn't any dietary changes that really help. My first IVF is in about a month and a half. I'm really hoping for a first time positive! Good luck! I don't really know of anyone else my age who have such high fsh.
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