Infertility

Medication Delivery Left Out in 5 Degree Temps, UGH

My big box of meds came earlier this week.  FedEx never rang the bell when they came and just dropped the box on my front stoop at 9 am.  All day I looked out the little window by the door and saw nothing. Finally at 6pm I opened the front door to investigate further and saw the package sitting there way off to the side and out of view of the window.  When I brought the box inside all the boxes of meds were freezing cold.  The temp high that day was about 5 degrees so well below freezing. 

All the boxes of meds and pills say to store them between 30 and 80 degrees.  I'm always a paranoid mess about my meds and having them sit outside in the very cold air for 8 hours makes me scared to inject them.  I did call the pharmacy and she said she's not concerned so I shouldn't be.  I know this all sounds silly, but I still can't shake the anxiety.  I start my meds tomorrow am after my baseline appt. 

Anyone have issues like this with their med delivery???

**** siggy warning - bfp & loss ****   ---- All Welcome ---

Me: 44 - Hashimoto's (under control), DH: 38 - (minor issues)


IUIs: 2 in 2012 ... Both BFN
IVF #1: 10/16/13 ... BFP, however it was not viable and ended in an early loss at 7weeks.

IVF #2: Feb '14 ... Cancelled. Positive beta at baseline appt, became very early loss.
IVF #2: Apr '
14 ... Retrieval Only. 2 embryos made it to day 3 freeze & will be batched with IVF #3 for PGD testing.
IVF #3: June '14
...
Retrieval Only. 4 embryos growing, all arrested before day 5. Two from April thawed, but also arrested.
Currently benched while determining how to proceed.

"Keep going until you can't fail"

 

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Re: Medication Delivery Left Out in 5 Degree Temps, UGH

  • I had to sign for all of my med deliveries. Since they were packed in a box, they should have been insulated some. If the pharmacy isn't concerned, I would try not to be concerned either.

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    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

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  • If you're really worried, I'd call your pharmacy and tell them what happened.  Ask to speak to a pharmacist about it (not the customer service)- they aren't out to make money and want to be sure everything is right.  Don't worry about it, but better safe than sorry if it's really bothering you.

    IVF #1 Oct 2013- cancelled 
    IVF #2 Mar 2014- success.... baby girl born 11/28/14
    FET #1 Mar 2016- baby boy due 12/16/16


  • All my meds come packed in ice, the label on most of them read to store them at x temperature but with excursions allowed to lower or higher temps for shorter periods of time.  I would think that the only thing that might be affected is if you have any oil based products or suppositories, check with your clinic or pharmacist on those. 
    Me 39, DH 40
    Male Factor (severe oligospermia) 
    IVF#1-December 2013: Conversion Protocol @ SIRM, Canceled on day 10 of stims due to poor response
    IVF#2- February 2014:  Estrogen Priming Conversion Protocol @ SIRM (ER 2/22: (9R, 7M, 4F, All arrested, nothing to trasnfer)
    IUI#1-May 28, 2014- 100mg clomid, HCG Trigger, 100mg progesterone oral--BFN
    IUI#2-June 24, 2014- non medicated, HCG 2,500mg x 4 doses (over a week), Endometrium- BFN
    Suprise BFP- September 1, 2014- miscarriage at 5 weeks. 

  • I agree with PP's.  If the pharmacist isn't concerned, don't worry.  

    I have had the opposite issue- our power went out for 27 hours and I had meds (gonal-f) that required refrigeration.  My pharmacist told me that as long as there were no visual changes (change in color, separation, smell) the main worry with that particular med would be a potential loss in effectiveness- basically moving the expiration date up.  Most likely, your expiration dates are months if not years away so if you are using the meds for an upcoming cycle, you shouldn't have any issue.  


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    Anniversary

    TTC since 2008
    Dh:34, no issues.  Me:31, Endo, slightly hypothyroid, deformed ovary, paracentric inversion.
    4 Gonal-F, Cetrotide, HcG, Crinone +TI cycles= all BFN
    Lap in 2012 to remove large unresolving cyst discovered endo and double lobed ovary.
     6 Gonal-F, Cetrotide, HcG, Crinone IUI cycles= All BFN,
    1st IVF w/ICSI- June '13 Antagonist: Gonal-F, Menopur, Ganirelix, HcG, Estradiol, Crinone= 7 retrieved, 4 mature, 1 unfertilized, 2 abnormally fertilized, 1 normally fertilized.  2DT of only embryo and our miracle BFP.
    Our beloved baby boy was born sleeping Oct. 13, 2013 due to pROM/IC/Uterine infection.
    2nd IVF w/ICSI- Feb. '14 EPP/lupron/antagonist: Estrace, lupron, HGH, Gonal-F, Menopur, HcG, PIO, lovenox, doxy/dex.=21 retrieved, 16 mature, 15 fertilized!!  5dt of 1 blast/ 6 frozen. BFP!  Beta 1 9dp5dt:83.9  Beta 2: 11dp5dt: 145.2  Beta 3  14dp5dt: 497  Please be our sticky rainbow baby!

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  • Thanks everyone!  Started my shots with microdose lupron today.  So far no issues, so I'm just going with it. I now realize it was prolly just a little crazy IF panic I was having.  All's good :)

    **** siggy warning - bfp & loss ****   ---- All Welcome ---

    Me: 44 - Hashimoto's (under control), DH: 38 - (minor issues)


    IUIs: 2 in 2012 ... Both BFN
    IVF #1: 10/16/13 ... BFP, however it was not viable and ended in an early loss at 7weeks.

    IVF #2: Feb '14 ... Cancelled. Positive beta at baseline appt, became very early loss.
    IVF #2: Apr '
    14 ... Retrieval Only. 2 embryos made it to day 3 freeze & will be batched with IVF #3 for PGD testing.
    IVF #3: June '14
    ...
    Retrieval Only. 4 embryos growing, all arrested before day 5. Two from April thawed, but also arrested.
    Currently benched while determining how to proceed.

    "Keep going until you can't fail"

     

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