Third-Party Reproduction

new this board. hi there.

I just found out that my two IVF banking cycles at CCRM failed. We got 4 embryos from the first IVF and 3 from the second. Only 2 embryos made it to blastocyst and CCS testing. They were both abnormal. It's devastating to have spent over $50k for nothing. Nothing to transfer. 

I'm grieving the loss of ever having my own biological child but considering other options. Does anyone have any recommendations for blogs or websites about egg donation? I'm not sure if it's the right path for us but need to do some research. 
Me: 36 - stage 2/3 endometriosis, diminished ovarian reserve (DOR), poor responder
Hubs: 37 - low morphology
TTC since 2008

Referred to local RE: 6/22/2010
HSG + Saline sonogram: 8/13/2010
IUI #1: BFN 09/2010
IUI #2: BFN 10/2010
IUI #3: + acupuncture: BFN 12/26/2010
Laparoscopy: Diagnosed and cleaned out endometriosis 1/9/2012
IVF#1 (ICSI): Long Lupron + acupuncture = Cancelled 1/11/2013
Second opinion phone consult with CCRM: 5/13/2013
ODWU at CCRM: 6/10/13
IVF #2 (ICSI): Estrogen Priming Protocol - ER 9/28/2013 = 7 eggs retrieved, 4 fertilized (banked and frozen at one cell stage for PGD testing with embies next retrieval)
IVF #3 (ICSI): Estrogen Priming Protocol - ER 1/10/14 = 8 eggs retrieved, 3 fertilized. My 4 from previous cycle were thawed at Day 1 to grow to Day 5 blastocyst phase with my 3 fresh embryos. Only 2 embryos made blastocyst and were biopsied for CCS testing. Both were abnormal. Nothing to transfer from either cycle. Told that I should move onto other options.Grieving loss of any biological children with my genes.

My blog: Dreaming of Dimples

Re: new this board. hi there.

  • I'm so sorry about your embryos. I did 4 OE IVFs to no avail. Donor eggs is not a sure thing so that's my first bit of advice. Do your research. Check out PVEDhttps://www.parentsviaeggdonation.org/, https://www.network54.com/Forum/57451/, google donor egg blogs. There are a ton of ways to do DE: dedicated cycles, shared/split cycles, agency donor, in house donor pool, frozen eggs, guarantee programs. Lots to consider.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • Loading the player...
  • The user and all related content has been deleted.
  • edited January 2014
    First, I'm so sorry you find yourself here.

    I used an egg donor right out of the gate as an OE cycle wasn't really an option. The first thing I'd suggest is talking to your RE if you have one you are attached to because they may have rules you'll need to consider. My RE required we use in-house donors or myeggbank.com which they are associated with.

    There is an overwhelming amount to consider, but figuring out what's most of a priority to you is a good first step. If its cost, you might want to consider RBA in Atlanta for a frozen cycle, or a shared cycle with a fresh donor at your clinic. If it's success rate and money is no object, head over to sart.com and find stats. There's an incredible place in Oregon with tremendous success, adult donor photos, etc, but the cost was outrageous compared to our clinic here in Seattle. I let go of adult donor photos and a few higher points in terms of success to save $10k.

    There are lots of donor egg moms and IPs here. Our weekly checkin (I just posted it) has "D-EG" after the names of donor egg peeps.

    Good luck on your next steps.
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

  • Just wanted to say welcome.  Not being able to use your own genetics is a big adjustment and takes a period of mourning, I think.  But donor eggs can be an amazing solution.  After much OE heartbreak I am now pg with donor eggs and couldn't imagine being happier even if I had used my own eggs. 

    I second McIrish's recommendation to look at PVED.  They have some good info write-ups on the site, plus message boards full of knowledgeable people.  There's a lot of knowledge on this site as well -- if you have questions, ask away.  The big choices are:  fresh or frozen eggs, guarantee program or not, in-house or agency donor, shared or exclusive cycle.  Here is PVED's FAQ page that addresses some of these issues:  https://pved.org/faq.php  The ladies here can give you feedback on these choices as well.  Good luck!


  • Grieving the loss of the biological link was the most difficult part for me. ((Hugs)) it's a really difficult time. I don't remember which blogs I looked at but I remember starting to feel good about DE when I first did a google search on "epigenetics donor egg".

    imageimageimage
    Lilypie First Birthday tickers
  • PP have given great info and I don't have any to add except to say "welcome"!

    TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own, autoimmune disease 3 Failed IUI's (2/2012, 4/2012, 6/2012) 
    IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d
    FET #1 December 2012, BFN
    FET #2 February 2013, no embies survived thaw
    IVF #2, BFP #2, Loss #2 March 2013, Scar tissue discovered, RPL testing,
    IVF #3, BFP #3, Loss #3 (twins) September 2013
    Hostile ute, moving onto Gestational Carrier!

    GC/FET #1 of 1 5AA blast and 1 compacted blast, February 2014, BFP #4 on 3/1/2014!
    6w u/s 1 bean with h/b of 145 bpm, 8w u/s 187 bpm
    EDD 11/7/14. Please, please, please stick little one!

    Praying unceasingly for a miracle. ALL welcome!

    image










  • thank you ladies. it is all so overwhelming and a lot to take in. but i appreciate all of the awesome information. guess its time to pick myself up by the bootstraps and start doing some research.
    Me: 36 - stage 2/3 endometriosis, diminished ovarian reserve (DOR), poor responder
    Hubs: 37 - low morphology
    TTC since 2008

    Referred to local RE: 6/22/2010
    HSG + Saline sonogram: 8/13/2010
    IUI #1: BFN 09/2010
    IUI #2: BFN 10/2010
    IUI #3: + acupuncture: BFN 12/26/2010
    Laparoscopy: Diagnosed and cleaned out endometriosis 1/9/2012
    IVF#1 (ICSI): Long Lupron + acupuncture = Cancelled 1/11/2013
    Second opinion phone consult with CCRM: 5/13/2013
    ODWU at CCRM: 6/10/13
    IVF #2 (ICSI): Estrogen Priming Protocol - ER 9/28/2013 = 7 eggs retrieved, 4 fertilized (banked and frozen at one cell stage for PGD testing with embies next retrieval)
    IVF #3 (ICSI): Estrogen Priming Protocol - ER 1/10/14 = 8 eggs retrieved, 3 fertilized. My 4 from previous cycle were thawed at Day 1 to grow to Day 5 blastocyst phase with my 3 fresh embryos. Only 2 embryos made blastocyst and were biopsied for CCS testing. Both were abnormal. Nothing to transfer from either cycle. Told that I should move onto other options.Grieving loss of any biological children with my genes.

    My blog: Dreaming of Dimples

  • Hi friend, and welcome. I'm so sorry you're in this difficult spot, but I can tell you that things do get easier with time. You hit the nail on the head - what you are feeling is GRIEF. It's being forced to let go of the dreams that come with a genetic child. But as with any other grief, moving through the process and allowing yourself to feel everything as it comes to you will help. Take good care of yourself in the process.

    One thing that really helped me was talking to a counselor that specialized in donor gametes. She talked to me about the concept of epi-genetics. There is a lot of research that supports the idea that the DNA of a baby is only a part of the makeup of a child. Many other factors are determined by the mother the baby is gestating inside of. Environmental factors play a big part in how the child develops and certain DNA traits are triggered or not triggered based on that mother.

    Also, if you think of your baby as a beautiful house, the DNA is just the blueprints. Everything else that builds this child comes from you - The framing, the pipes, the finishing touches....he/she is from your blood and tissue. There is a strong connection to a baby born of donor genes because of this alone. These concepts really helped me embrace using donor genes.

    I pray that you are able to find strength as you move forward and you'll have a great support group here to come to as you walk through the stages. I think of you often and hope that you'll find comfort and peace in your next steps.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • I also wanted to welcome you, but I'm sorry that you find yourself here.

    While many of the ladies here have had success, some of us have not (at least not yet). As @MrsMcIrish pointed out, it's important to know that TPR isn't always a quick fix and sometimes takes multiple times to work and sometimes just doesn't work. However, that said, it does provide a wonderful alternative especially if you know you don't have great eggs (or sperm) to work with.

    (Hugs) and welcome!

    Me: AMA, DOR, undetectable AMH, carrier of SMA, MTHFR homozygous C677T, high cytokines, low IGg B cells, Factor XIII V34l mutation, High Anti-Phosphatidylethanolmine, borderline hypothyroid and mildly insulin resistant.

     

    MH: No known issues, aside from MTHFR.

     

    Recommendations from RI: LIT, Humira, IVIG, Lovenox, Baby Aspirin, Folic Acid, Low-dose synthroid and Metformin.

     

    Currently taking:  Pre-Natal vitamins, Foltanx, Low-dose synthroid and Metformin. 

     

    When cycling also taking: Baby Aspirin, Lovenox, Humira and IVIG.

     

    TTC since 7/11/09..with medical intervention starting in 2010, including 4 failed IVF's and 6 failed IUI's...only "success" was a chemical pregnancy in 11/2012 (credited to use of DE).

    FET #1 (11th cycle) on 8/23/13 = BFN.

    FET #2 (12th cycle) Transfer of last two (day 6) donor egg blasts on 1/22/14 = BFP, EDD = 10/10/14 (please stick little BOY!)

     

    My favorite breed:

     

    image

    ***PAIF/SAIF always welcome***

  • So very sorry for your troubles. Welcome to the board and best of luck in your next attempt!!

    Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI   (TTC#1 since 2009)

    IVFs#1-4: (4/10-2/12) all BFN

    Surprise Bfp (9/11) - c/p

    DS IUI#1-2 (9/12, 10/12) - BFN

    DS IVF: (11/12) - BFN

    DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN

    FET of 2 day 6 blasts: (12/13) - c/p

    DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.

    FET 5/14: 1 day 5 hatching blast transferred...another BFFN

    Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus

    New RE, additional testing reveals elevated NK Cells

    FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October

     

     

     

  • Sorry to hear what you're going through.  We are in the process of using DS after failed ivf/icsi attempts.  It took me 3 + years to come around to this -  this is what our RE suggested the instant we got the results of our testing back then.  If I could I would go back and have used a donor then and hopefully been on baby #2 by now.   I turned into a bitter person, angry, hurt, for awhile and tried to hide my feelings with work, or staying busy for awhile.  It's been a long road to acceptance - I don't want anyone to suffer in infertility silence.  

    This isn't where I ever imagined we would be either. 

    Grief sucks.  I went to therapy.  Therapy helped me process enough to become wiling to go through ivf... and ultimately now ds.

    The bump helps when I need somewhere to retreat with other women who understand (I don't have any in my personal life at this time).  Keep posting
    Me (28) DH (34) - married and ttc since 2010.  dx w/ severe MFI 2011.  10/12 ivf w/ icsi, long lupron protocol, menopour etc. resulted in 3dt 2 embies bfp - beta 38, beta #2 numbers dropped to 22... early m/c.   4/13 ivf w/ icsi #2 = pushed hard on stims - all embies ceased on day 3, nothing to transfer and nothing to freeze.  ***Break from RE for sanity & $ .  IF is incredibly painful and I found that the grief process is chock full of suckiness.
    Currently: Accepting RE's original recommendation to use DS during IVF w. icsi as back up bc DH #s are so low. 
    AI w. DS 3x 1/23, 1/25, & 1/27.  8dpo- bfn, 9dpo- bfn. Hubby is calling me Pupo, <3 him.

    Important part of my story: 1.17.08: I lost my baby girl @ 21weeks. Pathology reported that she was "normal" and I was healthy.  I was high risk on modified bed rest when dx with case of placenta previa/ abruption which ultimately led to too much lost amniotic fluid. After weeks of bed rest and hospital stays; I had to say goodbye.  
    My arms have ached for my Juliette Marie ever since.

This discussion has been closed.
Choose Another Board
Search Boards
"
"