Ladies taking Ubiquinol/COQ10

jbasore1123 · January 2014

For those taking it, how much are you taking?

And does anyone know of any studies that says how long you need to be on it before it is effective?

katib77 · January 2014

I'm not currently on it, but was on it leading up to & during IVF cycle. Because men's sperm takes three months to go from being created to "coming out" RE had DH on it for the three months before our IVF so I just started at the same time since we got a large shipment. I don't even really know if women could just take it from AF on as that's when the egg follicles are developing, my RE didn't recommend it for my but gave me the "It couldn't hurt" talk. We were on 600mg daily. Prior to IVF, dh was only on 200mg a day for the last two IUIs and RE wanted that increased.

RunCC37 · January 2014

I'm taking 600mg daily of CoQ10 (300mg two times a day). I have read here and there that it takes three months to affect egg quality. I am not so sure about the credibility of those sources, but I'm hoping it's right!! I've been on CoQ10 for just over three months and am about to start with our next IVF cycle, so we'll see!

kz's_girlygirl · January 2014

I take 400mg/day. I've been taking it for 3 months, and we are starting our ivf in Feb. I took it for out last cycle as well. Last cycle I had crap eggs- only 4 out of 7 were mature, and only 1 out of that 4 fertilized (but I have a chromosomal issue that affects fertilization) so I am hoping for a better turn out this time.

From what I've read 3 mos is the prime starting time for most things, including vitamins. GL and hopefully it will give you a boost if you decide to take it!

LeggyJeggy · January 2014

I'm taking 600mg a day as well, split into 3 doses. I started it in the beginning of October so I would be on it for a good three months prior to our next cycle. I don't remember where I saw 3 months either, it might have been from the RE we went to for a second opinion - he was the one who suggested it for both of us (we're MFI and I've got poor egg quality/response to stims).

Twinkie0612 · January 2014

I took 300mg of Ubiquinol (advanced active form). I think it is equivilant to 600mg of regular CoQ10. I split it into 2 doses. I started taking it after IVF #1 in August (I stopped after tranfer for IVF #2 in October and started again after our c/p).

jlr96 · January 2014

I am taking 200 mg of Ubiquinol 3 times a day. I have also heard 3 months but not sure how accurate that is.

babydreams13 · January 2014

I started COQ10 200mg twice a day after my chemical with FET. I have been on it for one month now. I am on a break while trying to figure out what to do so I figure it can't hurt. DH is taking 200mg once a day too. I am also taking Royal Jelly.

ekc0630 · January 2014

I am taking 600mg of coq10. 300 2x a day. I too heard it takes 3 months to work. I start lupron on Feb 14th so I will let you know how it works. I am also taking royal jelly

Tenyearwait · January 2014

Same as pp. I am taking 600 mg of CoQ10 a day. I also heard 3 months.

jbasore1123 · January 2014

Where is everyone hearing 3 months from? Their doctor or other women on here? It takes sperm 3 months to mature, but not eggs

pblge · January 2014

@jbasore1123 said:

Where is everyone hearing 3 months from? Their doctor or other women on here? It takes sperm 3 months to mature, but not eggs

I've wondered if these got conflated at some point, too. I've never heard a reason for the 3 month guideline for women, but it does seem to be everywhere.

Miss43 · January 2015

I read it in this book https://www.itstartswiththeegg.com/

I had also read it in medical study articles that I accessed at my local library through a medical journal database.

they all said that while eggs are there when we're born, they do take a journey when they "called up" and that can take 3 to 4 months for them to make their way to a follicle.

emmuffy · January 2015

I also recommend It Starts with the Egg. I'm taking Ubiquinol 200mg/day

tptbabe · January 2015

Miss43 said:

I read it in this book https://www.itstartswiththeegg.com/
I had also read it in medical study articles that I accessed at my local library through a medical journal database.
they all said that while eggs are there when we're born, they do take a journey when they "called up" and that can take 3 to 4 months for them to make their way to a follicle.

Exactly this! In addition to it helping egg quality though, I've got to tell you that I feel fantastic since I started taking it! I'm on 400mg Ubiquinol (200mg 2Xday).

vballbaby · January 2015

I actually just started taking CoQ10 just when I started stimming for this cycle, so probably too late. However my one egg that fertilized was a 1 which is highest quality for day 2

I doubt it was that though but who knows. Mine is only 100 mg but apparently it's pharma grade (per my PHD Dr. friend who I buy them from)- don't know if that's even a legit way to describe it though? Does anyone know about the claim when something is "pharmaceutical grade"? It sounds good and all but I really don't know the difference.

7Kaby · February 2018

vballbaby
The answer is quite simple, very few supplement companies produce to a higher than required standard. If you google it, "pharmaceutical grade" simply means that the manufacturer has chosen to produce their supplements to the same high standard that medicine is produced in a plant without known allergens. They use higher quality raw materials and have stricter requirements for their manufacturing and the finished product - you can therefore feel good about the safety as you will not risk any weird extras in your supplements and there are no fillers or contaminants. Companies like Solaray, Pharma Nord, Gaia Herbs and Nordic Naturals have some of the best quality and yet still affordable products.

Ilky · February 2018

I'm taking 200mg Ubiquinol two times a day, equivalent to 800mg of CoQ10.

prudence9-2 · February 2018

I just found out that I’ll be having another IVF cycle. So I ordered some and will take it starting tomorrow. So I’ll end up taking 2 weeks before IVF and then during. It might be too late but maybe it will help anyway.

prudence9-2 · February 2018

Any other things you’re all doing for better egg quality?

libellula28 · February 2018

@prudence9-2

I believe the length should be at least 90 days, as that's the cycle of an egg?! Also, add some Acai supplements or berries! Apparently that increases IVF odds! I just started taking mine last week.

I take Vitamin D, B-Complex, DHEA, Acai, low level Aspirin, CoQ10. In 2 months of doing that, I raised my AMH from .29 to .628, it's not much in 2 months, but it is better than .29!!

ndz2018 · February 2018

@prudence9-2 I read some where that Vit D is effective for egg quality, I’m looking for the actual article I read and will post it when i find it but Dr Google has a ton of information on Vit D and egg quality.

My RE had me taking 300mg twice a day. I

tosh24 · February 2018

@prudence9-2 I was on 400 mg of ubiquinol/day plus my naturopath had me add in NAC which is a strong anti-oxidant that's REALLY good for egg quality. It bothered my tummy a bit so I dropped it and wasn't on it that long but stayed on the ubiquinol. Also on Vit D3 (was on 4000 IU/day because I was deficient, but once my levels came up to normal range I dropped to the typical 2000 IU/day dosage). B-complex vitamin is important as is folate (which you are probably already on). I suggest a methylfolate supplement rather than folic acid because it is already in its bioavailable form (and I am on a higher dose at 2000-3000 mcg/day total between my folate supplement and my PNV). Other than that, my naturopath has me on a good regimen to support my overall health in addition to egg quality which includes my PNV, a probiotic (the good quality kinds usually have to be kept in the fridge), Omega-3 (super important!!!) and vitamin C (good for reducing inflammation in the body). If your bank account is not completely sucked dry from all the fertility treatments (ugh!), I highly, highly, recommend setting up a consult with a naturopath that specializes in fertility. You really only have to go to about 2 sessions to get everything you need. I keep going to mine because I love her and I notice such a difference in my overall health that it's worth it aside from all the fertility stuff.

prudence9-2 · February 2018

Thanks everyone! Unfortunately I have only 2 weeks to prepare and not 90 days. I’m taking prenatal, some vit d+calcium. And from tonite I’ll start with the CoQ10.

dragonette505 · February 2018

It never hurts to start as soon as you can (even as antioxidants your body can use coQ10 right away)... the cycle of egg recruitment and maturation is about 90-120 days (90 days to mature enough for recruitment and then a cycle to ovulate or IVF)... heres a quote from a supplement site (fertility neutraceuticals)

Women are born with all their eggs, waiting in the ovary in an immature, dormant state. After women reach puberty, these immature eggs start to get "recruited" into the maturation process. At any given moment during a woman's reproductive life span, hundreds to thousands of eggs are in various stages of maturation. Only one of these eggs usually reaches full maturity and is released from the ovary (ovulation) each month for possible fertilization and pregnancy.

The figure above describes this maturation process of eggs. The process in the ovary takes at least 120 days from start (pre-antral follicles) to finish (ovulation), sometimes taking even a little longer. In order for immature follicles to develop into good-quality eggs during this 120-day journey, the entire process should preferably take place in an ovarian hormonal environment that encourages healthy maturation of eggs.

Hope this helps!

prudence9-2 · February 2018

@dragonette505 yep. I know that. But i found out about doing another IVF cycle this week and I start in 2 weeks. So I’ll start with what I can. But I won’t have 90 days

dragonette505 · February 2018

prudence9-2 said:

@dragonette505 yep. I know that. But i found out about doing another IVF cycle this week and I start in 2 weeks. So I’ll start with what I can. But I won’t have 90 days

No i get it... but coQ10 can be used by your body right away... i had a doc tell me that the extra c0q10 may help with adding more energy for meiosis which can make the difference between normal and abnormal embies. 3 months is best but even a few weeks can help!

prudence9-2 · February 2018

@dragonette505 yeah. I hope so. This will be my last attempt at IVF. So I’m hoping for better results than last time. (Which is tough as I was almost 1.5 years younger when I did IVF last)

stephanienj · February 2018

@prudence9-2 . My RE only suggested starting Coq10 a few weeks before my retrieval, but I had already started it as soon as I knew we were going to do IVF (about 3 weeks ago), so it'll only be about 6 weeks total. I also starting taking some other supplements that I've read up on.
I take: Coq10- 200mg 3 times a day. Multi Vit. Vitamin D 1000, 2 times a day (my level was low on blood work, so I was taking this regardless as ordered by my regular endocrinologist who I follow for my thyroid, or lack thereof), Omega 3, fish oil twice a day. Vitamin C- 1000mg twice a day. 400u Vit E once a day. My hormone levels aren't really bad, our biggest battle is severe MFI, so I have hubby taking all of that too, as well as Acytal Carnitine, Arginine, Maca, and Grape Seed.

prudence9-2 · February 2018

@stephanienj I’ll start taking CoQ10 tonite. The box I ordered has 200mg pills and it says to take 1 daily. But I see all of you taking 600mg. Is that the recommended amount?

dragonette505 · February 2018

prudence9-2 said:

@stephanienj I’ll start taking CoQ10 tonite. The box I ordered has 200mg pills and it says to take 1 daily. But I see all of you taking 600mg. Is that the recommended amount?

I’m recommended 600-900 (some brands go up to almost 1000 recommended by chr).
i take 600 right now but was taking 900 ahead of cycles.... overkill, maybe, but I’m old!

prudence9-2 · February 2018

@dragonette505 I’m old too

almost 42.5... so just take one pill 3-4 times a day?

dragonette505 · February 2018

prudence9-2 said:

@dragonette505 I’m old too almost 42.5... so just take one pill 3-4 times a day?

yup! thats the easiest way. I was using the expensive stuff (https://fertilitysupplementstore.com/ovoenergen/)
and they have it broken down to three pills a day. Im now using a cheap Amazon coQ10 (ubiquinol) thats 300 per pill so im doing the same thing. As i head into my FET I'm going back to the ovoenergen stuff though.

stephanienj · February 2018

@dragonette505 - The 600mg per day was ordered by my RE. I ordered from Amazon, was able to get a decent sized bottle of 200mg for about $15. Far Far cheaper than buying them in the pharmacy, but I find amazon's vitamins and supplements are all pretty competitively priced.

prudence9-2 · February 2018

@stephanienj @dragonette505 I got mine at amazon too. 60 200mg pills for about $14. And they are also vegan. Which is always a plus for me (I’m a vegetarian. And most pills have fish products in them which I rather not use).

stephanienj · February 2018

@prudence9-2 can't beat amazon's prices- I just looked at mine- it was 120ct, but mine aren't vegan.

dragonette505 · February 2018

prudence9-2 said:

@stephanienj @dragonette505 I got mine at amazon too. 60 200mg pills for about $14. And they are also vegan. Which is always a plus for me (I’m a vegetarian. And most pills have fish products in them which I rather not use).

yeah, i get many of my supps from amazon (even some from the companies my docs specifically want me to use and have website codes for i can also get for the same price on Amazon!) but i do like to power up on my coq10 when doing a cycle (thus the fertility neutraceuticals brand)

prudence9-2 · February 2018

@stephanienj yep. Amazon the the Best. also my prenatal are from amazon. And also vegan

Knottie60076601 · February 2018

I have been taking CoQ10 since we started IVF last year. For our most recent cycle, I upped my dose from 200mg to 400mg daily and it was our most successful cycle yet in terms of egg production. Still no BFP, but a step in the right direction! I will caution that it tends to mess with my sleep so I never take it later than 2pm.

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