IUI for MFI (morphology) ?

bcw2009 · January 2014

Hey Ladies,
I am gearing up for my RE appt on Tuesday where we will develop at medication/treatment plan. We have been working with him since Sept and only done diagnostics thus far so I am really ready to hear what he recommends as far as treatment. My guess from family/friends experiences and the internet is that we will start with IUI? So far our diagnosis is borderline low morph (5% in Sept and 9% in Dec)/unexplained. I am just curious to know what your thoughts/experiences are on IUI success for morphology/unexplained. I don't have much data but a strong gut feeling that IUI is just not going to do much for us

I understand how IUI would be beneficial if you needed to trigger ovulation or if there was a motility issue it would get the sperm closer to the tubes. For morphology what would the rational be for IUI and how much does it really increase our chances of conception?
TIA!!

Momarazzi007 · January 2014

IUI may not be first step, what are his numbers? If below, what 5, 15 mil? (Help me ladies my hubs has never been above 3) then IVF w ICSI would be recommended route, not enough for IUI to really work. That being said, if only 5% are good morphology, but those are a good number, whatever high millions, IUI could still be option because of sheer numbers. It's a numbers game, after all motility and morphology are considered.

cerad5 · January 2014

I agree with PP, from what my RE explained morphology wasn't as big of a deal if the count is really high, or at least normal. For instance my DH's morph was around 5% I think, but his count was 95mil so the RE wasn't concerned. Also I believe some RE's use different criteria, Kruger model vs others which changes the percentages around.

Momarazzi007 · January 2014

95 mill? Holy cow! We got a stud!!!

lol, sorry I'm just amazed by numbers... Like I said highest hubs ever had was 3!

EmilyB15 · January 2014

DH's morphology was only 1% Kruger. He was dxed with mild MFI. But he had really good count and good motility. Our first RE recommended IUI. We did 1 IUI and it failed. The second month we chose to skip IUI and do TI and we got pregnant. We are now seeing a new RE (due to a move) and he said he would never recommend IUI for low morphology. He recommended TI, which is what we are doing. I agree that morphology is the least important 'defect' in sperm and IUI is not necessary unless there is a low sperm count or motility issue. Also, IUI is not really fun. DH felt so uncomfortable with the whole thing and his count on the day of the IUI was really bad. He put it down to performance anxiety and he thought that was the reason I didn't get KU that cycle! For us, it has been much better to do TI since it is more relaxing for both DH and I.

cerad5 · January 2014

Momarazzi007 said:

95 mill? Holy cow! We got a stud!!! lol, sorry I'm just amazed by numbers... Like I said highest hubs ever had was 3!

Sorry, I don't intend to sound braggy. He's got a great count but I make crappy eggs.

bcw2009 · January 2014

Thanks ladies! I appreciate your thoughts. I am just being impatient now that my appt is right around the corner and doing a lot of speculating about what might be ahead in our future...

Momarazzi007 · January 2014

Cerad5- No no no!!! Didn't think you were being braggy at all! We all have infertility, some male, some female, some both! I just thought it was a great number and was trying to be happy for you in a funny way that you have that going for you!

cerad5 · January 2014

Momarazzi007 said:

Cerad5- No no no!!! Didn't think you were being braggy at all! We all have infertility, some male, some female, some both! I just thought it was a great number and was trying to be happy for you in a funny way that you have that going for you!

Oh good, just making sure

Jen071407 · January 2014

I somehow missed this post 8-} MH's first SA over a year ago came back with 3.5% strict morph, but high count (I think 70mil that time). My RE also said the high count can outweigh the low morph. MH just had a repeat SA and his strict was up to 10%, so it really can change. In regards to IUI, we've done 6 and 1 resulted in a pregnancy - I also have crap eggs though, and this last IUI was pretty much thrown out the window when I got a fever/stomach bug the day after, so 1/5 I guess. So if his count is high and you're "normal", then I'd say go for a couple IUIs, especially if insurance covers it. IUIs will also involve washing the sperm, which typically leads to an even better sample that is used.

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