I know we were just talking about PIO injections the other day, but what about the welts that last days? My poor butt is so sore. Anyone with helpful hints for after injections? (I already ice before and use heat after...but the spot I injected 2 days ago is still sore and welted).
Re: OhMyGosh my butt cheeks.
***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage.
Are you massaging the spot after injection? I don't ice before, but I lay down flat in bed, then have DH do the injection and massage the spot for a few minutes. I apply heat for 10-15 minutes and then try to get up afterwards and walk around. I have never had a problem with knots or welts.
It could also be the type of oil. I know some women are sensitive to certain oils.
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
Hopefully that helps, some oils are thicker and might need more help spreading out. I think I usually get Progesterone in ethyl oleate, which I think is a little thinner than say sesame oil. I have a few donated vials this cycle that are in sesame oil, so I might end up in the same boat as you.
Ooh thought of something else. Do you warm the PIO before injecting? Some women warm it with their body heat or run they syringe under warm water. I've never done this but some swear it helps.
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
TTC Since 12/2008; DH: 32, Azoospermia me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due
to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder
High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder
IVF w/ ICSI #1 2/2011 IVF w/ ICSI #2 5/2011 IVF w/ ICSI #3 12/2012 *New RE* IVF w/ ICSI #4 5/2013
IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
IUI #1 12/23- BFN IUI #2 Cancelled (ovulated during AF) Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12, Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week- Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x, Femera & Menopur
IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766 EDD: 3/23/2015
ET 9/10 - transferred 1 perfect 5AA blast
7dp5dt BFP ~~ Beta on 9/19 - 77.4 Beta #2 on 9/21 - 357
Low heartbeat on 10/7 86, lower heartbeat on 10/11 76, no heartbeat 10/14/13. D&C 10/15/13
Tests revealed MTHFR c677t mutation, put on Folgard.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
FET #1 1/6/14 - 4BB blast - BFN
TTC Since 12/2008; DH: 32, Azoospermia me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due
to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder
High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder
IVF w/ ICSI #1 2/2011 IVF w/ ICSI #2 5/2011 IVF w/ ICSI #3 12/2012 *New RE* IVF w/ ICSI #4 5/2013
IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
IUI #1 12/23- BFN IUI #2 Cancelled (ovulated during AF) Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12, Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week- Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x, Femera & Menopur
IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766 EDD: 3/23/2015
************** Siggy Warning************
Married August 2012 -- Me (40 yrs old) My husband (45 yrs. old)
RE referral from ObGYN in late Jan. 2013 -- Testing Confirms Unexplained IF
IUI #"s1 - 3 (Femara + IUI) April - June 2013 - all BFN
Decided to do IVF... Began stimming on September 10th! Egg Retrieval 9/20/13. 19 eggs: 6 to mature to freeze after 6 fertilized with ICSI
3 morula stage embryos transferred on 9/25/13.....Beta #1 on 10/4/13/ = 7.5 Beta #2 on 10/6/13 = negative
IVF#2 - Lupron plan (set to begin on 10/28/13) (Planning on thawing and fertilizing our 6 eggs with ICSI as well as all of the mature eggs they retrieve with this fresh cycle.)
Late October 2013 - ectopic pregnancy - methotrexate injection....benched 3 months
CD1 - 12/5/13...Lupron set to start on 12/26/13; CD1 - 1/2/14....Baseline 1/3/14....begin follistim tonight and continue with lupron. (Got my calendar today! IVF#2 is a go!)
ER = 1/14/14 (11 eggs....9 were mature. 9 fertilized. Of the 6 mature eggs we thawed, only 4 fertilized. At this time, we have 13 eggs fertilized and growing. Waiting for news about a 3-day or 5-day transfer.)
ET = 1/19/14 (5dt).....3 blastocysts transferred! (All nine embryos didn't make it to freeze. =( )
Beta #1 = 1/28/14 (2 weeks after ER) BFP! 209 (9dp5dt) EDD 10/7/14
Beta #2 - 1/30/14 (11 dp5dt) 302
Beta #3 - 2/3/14 (15 dp5dt) 1222
Ultrasound set for 2/17/14......TWINS! Twin A - HR 124 bpm; Twin B - HR 126 bpm
Final Ultrasound with RE 3/10/14 - Twin A - HR 176 bpm; Twin B - HR 177 bpm.
PAIF/SAIF Welcome!
The first night I just sat down afterward and ate chocolate... could barely sit the next day. The second night DH rubbed it for a while after the shot and it was a bit better. Last night I had to be a warrior and do the shot on my own (while looking in the mirror and questioning my life)... afterwards I was up and down stairs putting away laundry, cleaning, etc. Even better today. So for me, the medicine seems to absorb better/break up easier if I move around.
2013: BFP #1 - M/C 3/13
2015: Dance break = got healthy
7/2016: IVF #5 = BFP!!!
This made me LOL! I'm glad this was posted since I'm headed this route. My RE said that I must be metabolizing the suppositories too fast since AF usually starts 10 days after I start taking them.
Me: 32 | He: 35
TTC since Sept 2011
DX: Unexplained
1st round of clomid: Jan 2013 BFP - M/C 8 weeks
surprise BFP Apr 2013 - M/C 9 weeks
IUI #1 clomid Jul 2013 = BFN
IUI #2 clomid Aug 2013 = BFN
IUI #3 injects Oct 2013 = BFN
IUI #4 injects Dec 2013 = BFN
IVF #1 March 2014 - 12R/12F, one perfect day 5 blast transferred
BFP!! Beta#1 = 431 Beta#2 = 914 Beta#3 = 2207
PAIF/SAIF Welcome!
It's twin girls!! Born on 11-2-14!
Me: 32, DH: 34 / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d
5/27/2014: Team purple!!!! EDD 10/10/2014 /
Baby Boy 4lbs 1oz, 17 inches
Baby Girl 3lbs 5oz, 16 inches
09/12 lap/hysteroscopy =removal of mass on bladder, possible blocked tubes
12/12 hysteroscopy=tubes clear. uterine septum removed
01/13 fermara step up + iui=cancelled due to no response
02/13 clomid step up + iui=cancelled due to no response
07/13 gonal-f + trigger + b2b iui = bfn
08/13 bravelle(slow response) switched to menopur + trigger + b2b iui = bfn
10/13 - IVF#1 w/ ICIS. ER= 10/29/13 (21R 10F 6 blasts made it to freeze)
11/25/13 - FET #1, transfer 2=bfn
03/03/14 - FET #2, transfer 2 frosties=BFP! beta#1=22, beta#2=43, beta#3=120. Ectopic Pregnancy 6w5d
07/31/14 - FET #3, transfer our last two.
2013: BFP #1 - M/C 3/13
2015: Dance break = got healthy
7/2016: IVF #5 = BFP!!!
Me: 32, DH: 34 / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d
5/27/2014: Team purple!!!! EDD 10/10/2014 /
Baby Boy 4lbs 1oz, 17 inches
Baby Girl 3lbs 5oz, 16 inches
Me: 32, DH: 34 / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d
5/27/2014: Team purple!!!! EDD 10/10/2014 /
Baby Boy 4lbs 1oz, 17 inches
Baby Girl 3lbs 5oz, 16 inches
2013: BFP #1 - M/C 3/13
2015: Dance break = got healthy
7/2016: IVF #5 = BFP!!!
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
I'm weird and obsessive about following directions so we use a sterile gauze pad. But tonight, for some sweet action, I'm going to wrap some cotton balls in it.
2013: BFP #1 - M/C 3/13
2015: Dance break = got healthy
7/2016: IVF #5 = BFP!!!
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
It's twin girls!! Born on 11-2-14!
2013: BFP #1 - M/C 3/13
2015: Dance break = got healthy
7/2016: IVF #5 = BFP!!!
ET 9/10 - transferred 1 perfect 5AA blast
7dp5dt BFP ~~ Beta on 9/19 - 77.4 Beta #2 on 9/21 - 357
Low heartbeat on 10/7 86, lower heartbeat on 10/11 76, no heartbeat 10/14/13. D&C 10/15/13
Tests revealed MTHFR c677t mutation, put on Folgard.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
FET #1 1/6/14 - 4BB blast - BFN
Me: 32, DH: 34 / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d
5/27/2014: Team purple!!!! EDD 10/10/2014 /
Baby Boy 4lbs 1oz, 17 inches
Baby Girl 3lbs 5oz, 16 inches
TTC #1 since June 2012
Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
DH (29) - MFI low count and morphology
September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN
Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
Results: Cancelled after 11 days of stims due to low response and E2 levels
Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
Results: 1 retrieved / 0 mature = Cancelled after ER
Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours
It's twin girls!! Born on 11-2-14!
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!