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Decrease in stim dose

BRaven985BRaven985 member
edited January 2014 in Infertility
I have done 4 days of stims...tonight will be 5.  Went in this morning for a check and got the message to lower my dose and come back tomorrow.  For some reason the results aren't in the system so I don't know the specifics (or my E2 at all) but I did have some follies this morning that were in the 10-11 range.  Last time at this point they were all less than 9.  I always hear people getting an increase...but not a decrease.  Does this mean I am moving too fast?  I am high risk for OHSS based on having had it before so not sure if that is part of the reason for the decrease.  Anyone have their stims lowered in the past?

ETA: Went from 100 to 75 for Follistim and 150 to 75 for Menopur
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Me: 36, unexplained 
Him: 36, slightly low count 
TTC since May 2011 
IUI #1 w/Clomid - 10/2012 BFN 
Break for cysts 
IUI #2 w/Clomid - 12/2012 BFN 
Break for cysts 
IUI #3 w/Clomid - 2/2013 BFN 
Break for sanity and to work on health with diet, exercise, and acupuncture 
IVF/ICSI #1 - BCP, 150 Follistim, 150 Menopur, and Ganirelix
Retrieval 9/11/2013 - 31 eggs, 17 fertilized, 3 blasts frozen 
Transfer cancelled - Moderate OHSS 
FET #1 - 10/22/2013 Transferred 2 (1 did not survive thaw) BFP resulted in CP 
IVF/ICSI #2 - EPP - Starting stims 1/5/2014 (100 Follistim, 150 Menopur)
All welcome!


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Re: Decrease in stim dose

  • pblgepblge member
    edited January 2014
    A decrease is usually good news, as it means you're responding well and they want to slow you down. I think this is definitely due to concern about OHSS. Some women, myself included, are very sensitive to these meds, and you may be one of them.

    Good luck, and don't worry!
    **********************siggy/ticker warning**********************

    ***Losses mentioned.*** TTC #1 since May 2012. Me: 37, OH: 41. Ectopic August 2012 => tubal damage. :'(  Stage 1 endo removed June 2013. IVF #1 Oct/Nov 2013: Long Lupron with Gonal-F. 7R, 7M, 7F. 2 txfer@3d. Nothing frozen.  => M/C @ 8 wks. :'( Selected RPL panel all normal. Very hyper and brittle response to stims. IVF #2 (antagonist protocol) Feb 2014 => Converted to IUI (Perfect conditions). BFN. IVF #2.1 w/ new RE June 2014: Antagonist protocol. 33R, 31M, 30F, 19 blasts to test!!! I made it through without crashing!! :) Hats off to Dr. Fancypants!! ET of one 5AB blast. BFN. 13 10 CCS'ed snowflakes! FET #1 PUPO as of 7/29 Betas: 8/7@24, 8/9@97, 8/11@334 (etc.) Two sacs on 8/15, one seen on 8/18 after a bleed. U/s 8/25 (6+3) "perfect": 5.9 mm + HB@120bpm! U/s 9/4 (7+6): 15.9 mm + HB@172 bpm! Please, PLEASE stick this time!!!!
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  • BRaven985BRaven985 member
    Thanks @pblge I am worried about the OHSS....hopefully this decrease will get that under control.  I just wasn't sure if moving too fast had any other concerns.
    image
    Me: 36, unexplained 
    Him: 36, slightly low count 
    TTC since May 2011 
    IUI #1 w/Clomid - 10/2012 BFN 
    Break for cysts 
    IUI #2 w/Clomid - 12/2012 BFN 
    Break for cysts 
    IUI #3 w/Clomid - 2/2013 BFN 
    Break for sanity and to work on health with diet, exercise, and acupuncture 
    IVF/ICSI #1 - BCP, 150 Follistim, 150 Menopur, and Ganirelix
    Retrieval 9/11/2013 - 31 eggs, 17 fertilized, 3 blasts frozen 
    Transfer cancelled - Moderate OHSS 
    FET #1 - 10/22/2013 Transferred 2 (1 did not survive thaw) BFP resulted in CP 
    IVF/ICSI #2 - EPP - Starting stims 1/5/2014 (100 Follistim, 150 Menopur)
    All welcome!


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  • absolutelymaybeabsolutelymaybe member
    edited January 2014
    I'm glad you asked this question. I was on 225 of Gonal F to start. On day 3 went in for ultrasound and had about 25 small follicles and four that were slightly larger (8-10mm). They reduced my Gonal F to 150. I didn't ask why but assumed it was a good thing. 

    N14 Nov. Siggy: CELEBRATION!
    image image
    TTC since 2011
    Aug. - Sept. 2013 - dIUIs = BFNs
    January 2014 - IVF = 3 freezer babies
    March 2014 - FET of AA and AB blast = BFP! Twins! 
    Nov. 7, 2014 - Wilhelmina "Willa" Suzanne (4lb 14oz) and Ari Jose (6lb 4oz) were born via CS
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    image image image image 

    Lilypie Premature Baby tickers
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  • jbasore1123jbasore1123 member
    My doc decreases me even before I go in for an u/s.

    TTC since April 2012

    BFP #1, 10/03/2012 - EDD 6/15/2013 - MMC 11/15/2012 - D&C 01/04/2013

    BFP #2, 04/06/2013 - EDD 12/17/2013 - MC 04/19/2013

    6/12/2013 Diagnosed with Balanced Translocation (12 & 16)

    IVF #1 with PGS: 10/2013: Canceled 9/27/2013 for issues with genetic lab

    IVF #1.5 with PGS: 11/16/2013: Canceled. 11 eggs retrieved, 9 mature & 9 fertilized, all unhealthy embryos

    IVF #2: 1/22/14: Canceled. 16 eggs retrieved, 14 mature, 7 fertilized, all unhealthy embryos

    IVF #3 with PGS: 5/10/2014: Switched to FET in July. 10 eggs retrieved, 9 mature, 8 fertilized, 2 healthy embryos!

    FET #1: 7/31/2014: Transferred 2 nearly perfect (6AA, 6BA) healthy embryos- BFFN

    Laproscopy: 10/2014: Healthy uterus

    IVF #4: 12/8/2014: Canceled. 17 eggs retrieved, 15 mature, 10 fertilized, all unhealthy embryos



    Lilypie Angel and Memorial tickers

    Lilypie Angel and Memorial tickers

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  • LSN8308LSN8308 member
    yes its to prevent OHSS. i was always decreased on all 3 IVFs and coasted on 2 of them. its a good thing and hopefully they know how to maintain your levels so u can do a fresh transfer hopefully FXXXXX for u!!
    **SIGGY TICKER WARNING**
    Me: 27 High FSH (POF?) DH: 33 Slightly Low Morphology / Married Aug '08 TTC since 7/2009
    6 rounds of clomid = no luck
    IVF w/ ICSI & AZH #1 - Jan/2011 = ET cancelled OHSS
    FET #1 & #2 - March/2011 & June/2011 = Chemical Preg.
    IVF w/ Half ICSI #2 New RE - May/2012 = BFN!
    May '12 - Sep '13 - Took A Break
    Dec '13 IVF w/ Half ICSI #3!!!!! Switched RE
    Protocol - Lupron trigger/Follistim/Ganirelix/Estrace/Vivelle/Crinone
    12/27 - BFP! TWINS! EDD 9/3/14 ...Team PURPLE!
    6/27/14 - Emergency C/S @ 30w2d - Baby A 2lb 14oz, Baby B 2lb 11 oz
    image
    ALL WELCOME :)
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  • FloridaSun82FloridaSun82 member
    I had a decrease in mine after a couple of days, too. Mine was because they were worried that my E2 was getting too high, but I did not end up with OHSS. 
    Me (31) - PCOS with insulin resistance

    4 rounds of Clomid = no response
    IVF # 1 - ET (1 3AA, 4 frosties): 12/22 = BFP
    EDD: 9/9/2014

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