Infertility Veterans

medical records opened a can of worms....

I recently recieved my medical records from the RE because we will be going for a second opinion Monday and now looking closer at some things, there were some major red flags....Any input is appreciated!
first of all, in all of my husbands SA (but I will be specifically talking about the last one we used for transfer), he only had 6 total sperm 2 motile and 100% forward progression....gradient prep (anyone know what this is?) yielded 23 total sperm, 2 motile, 0% forward progression. Morphology showed head shape defects, double tails and pin heads!!!!   WTF....im guessing this is all bad and will ICSI even work!  I am so ticked we weren't given these details....when asked about the samples they always said they were "good enough" and only talked about totals and motility....never about morphology.  and here is my last cycle details....

 

10/25

 

 

110

 

6.12

 

11/1

 

 

402

 

10.73

 

11/8

 

 

526.81

 

8.61

 

11/15

 

 

261.57

 

N/A

 

11/17

 

 

108.82 *started stimulation

 

N/A

 

11/22

 

 

409

 

8.84

 

11/24

 

 

627.43

 

7.58

 

11/26

 

 

933.46

 

 

11/28

 

 

1260.37

 

 

11/29

 

 

1177.38

 

6.07

notice the lining decrease....I only found out about this on my last monitoring appointment....and also, my E2 levels dropped the last monitoring appointment...
I am now obsessing again over stupid IF!!!!!!  I think I found myself a new job....I will be doing lots of researching in the next few days for sure!

TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each)
IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt.   Beta hell.  #1 2.5, #2 2.2- BFFFN! REALLY?
IVF #3: ER 12/1 and only 2 retrieved.  1 fertilized with ICSI.  Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
IVF #4: Antagonist protocol with endometrial scratch day one of stims.  ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching!  No frosties but hoping we won't need it!  Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002!  THIS HAS GOT TO BE IT!!!!!!!!!!  First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!  
****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!  

BRINLEY AND RILEY LONG.  Born November 20, 2014 at 32 wks 3 days.  4lbs7oz and 4lbs5oz.  1 month NICU time for "B's" and growing and feeding.  Now healthy, thriving, beautiful little girls!
 imagehttp://i62.tinypic.com/2dl9ap0.jpgpghttp://oi61.tinypic.com/o7t1y0.jpg

Re: medical records opened a can of worms....

  • As for the sperm that is very poor if your husband were a stallion he would be snipped and sold as a gelding as you can't get anything viable from that I only say it this way because I went to school for this.

    You can't icsi double headed sperm or ones that go in circles unless you try and manipulate them which it sounds like they put a solution in there to do. I have a call but will give you more detail later

    Hugs
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


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  • I am so sorry that you were blind-sided by this.  I would be upset too.  Huge hugs.


    ***SIGNATURE WARNING***


    TTC #1

    Me 42, DH 47

    Dx = AMA/DOR, MFI

    IVF/ICSI #1 = BFN

    IVF/ICSI #2 = BFP; early loss

    IVF/ICSI #3 (DE) = BFP; early loss

    FET = BFN

    IVF/ICSI #4 (DE w/ CCS) = BFP

    Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

    1st U/S @ 6w2d showed one perfect little heartbeat! 

    2nd U/S @ 7w2d. HB 132 & everything measuring on track.

    Our beautiful little girl arrived January 2015!


  • I'm glad you're going for a 2nd opinion. FX the new RE will be able to give you some answers. ((hugs))

    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 29 ~ perfect swimmers

    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN

    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013
    ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple
    G&B born 6/30/14 at 33w3d via emergency c/s.


    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


    image

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  • luvbostonluvboston member
    edited January 2014
    Ok so let me try to explain this when you get a sperm sample in to the lab there is debris etc that has to be washed off. There are many different ways to do this and also many solutions. In many cases a centrifuge is used with added solution to get the debris caught and then the ability to draw it out is easy. The issue with this is that it can destroy sperm and motility.

    In your husbands case they used way to much fluid to do this and ruined the motility. There was a study done by NIH that's said sperm motility is drastically reduced by 100% fluid. Also the method they used was too strong for the sperm from the little you have told me. Also when you look at sperm you want to see most of them moving forward with good tails and heads not spinning in circles having weird shapes when you do a sperm count all this info is on their when your DH had this stuff checked what numbers did he get?

    There are also methods to improve motility also used in your case but they have pitfalls as well.

    If the sperm were like this I would have suggested freezing eggs and getting a better sample or using ds.
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


  • Thanks so much luvboston. I am so happy we are getting a second opinion! I feel so blindsided!
    TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each)
    IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
    FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
    IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt.   Beta hell.  #1 2.5, #2 2.2- BFFFN! REALLY?
    IVF #3: ER 12/1 and only 2 retrieved.  1 fertilized with ICSI.  Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
    IVF #4: Antagonist protocol with endometrial scratch day one of stims.  ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching!  No frosties but hoping we won't need it!  Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002!  THIS HAS GOT TO BE IT!!!!!!!!!!  First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!  
    ****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!  

    BRINLEY AND RILEY LONG.  Born November 20, 2014 at 32 wks 3 days.  4lbs7oz and 4lbs5oz.  1 month NICU time for "B's" and growing and feeding.  Now healthy, thriving, beautiful little girls!
     imagehttp://i62.tinypic.com/2dl9ap0.jpgpghttp://oi61.tinypic.com/o7t1y0.jpg

  • I'm so sorry. I know when I got my records there were a few things not mentioned to me as well. Just wondering, did you just start PIO when your lining went down? I know its normal for it to thin out once you start it.  ((hugs))
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
    image
    image


  • I'm sorry that the records gave you even more questions. I think the second opinion is a good idea. You have some hard choices to make going forward which may be continuing to keep trying IVF or adding in a third party option. No one ever wants to hear this. I remember a doctor saying to me "do you want a baby now or can you wait for one? If you can wait, keep trying with OEs. It may happen. If you don't want to wait, a donor may get you there quicker". This applies for both eggs and sperm. There's no right answer but its awfully painful to experience. Hugs.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • ((Hugs))  I wish you the very best.  I agree a second opinion is a good idea.  ((More hugs))
    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
  • I agree with the second opinion. It sucks to find out after the fact that the environment was not ideal. I remember looking at my records of failed cycles thinking - why didn't they say anything to me? Don't I have the right to know? Sending you many hugs.
    TTC 1/2010 DH Dx - Azoospermia 2/2011
    Hysteroscopy 3/2011 2 Polyps removed 4/2011
    DH on Clomid / Arimidex to address hormonal issues - Sperm found July 2011!
    IVF #1 September 2011 - ER 9/8/2011- 8R, 5M - icsi - 1 made it to transfer - BFFN :-(
    IVF #2 Lucky November 2011 - ER 11/25/2011 - 15 eggs!, 13 mature, 10 fertilized with isci - 7 made it to transfer! Transferred 1 - 8 cell and 2 - 7 cell. BFP!!!!
    1st U/S - Twins! 2nd U/S - 3 heartbeats!!! - HOLY COW!!!
    Prayers for our take home babies!
    2 babies born on 3/27/12 and lost. Last baby born on 3/29/12 and lost at 20 weeks.
    My angels grew wings shortly after birth.
    Ahava Raisel, Matisyahu Nissim & Zev Chaim - Mommy and Daddy will always love you.
    IVF #3 July 2012 - ER 7/17/2012 - 10 R. 5 F. 4 made it to ET
    Transferred 2 on 7/20/2012 no snow babies :-(
    Beta on 7/31/2012 = BFMFN
    A miracle gift expected to come to us through adoption around 9/2012
    Baby girl adopted - Birth Mother changed her mind and took the baby back
    IVF #4 October 2012 - New RE. Doing PGD Testing. 8 R, 7F, 2 made it to 5 day blast for PDG testing. Both Normal (Thank you G-d!!!) 1 boy and 1 girl
    transferred one beautiful 5day blast (girl)
    Please G-d the almighty one - let this be our take home baby!
    Beta #1 158, Beta #2 318, 1 Absolutely magnificent HB at 175! Thank you G-d!!!
    Baby Girl born August 5th. Thank you G-d for our precious miracle.
    AMA. PAIF & SAIF always welcome - I need all the prayers I can get!

    Lilypie Angel and Memorial tickers
  • That's really obnoxious. I'm so sorry you had to find out things were not as you were lead to believe.

    I would definitely get a second opinion, but try to keep an open mind.

    I have always left a clinic after I felt like they didnt have our best interest at heart or I couldn't trust them.
    Sounds like you're done with them.

    Hoping for only the best for you as you move forward.

    Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI   (TTC#1 since 2009)

    IVFs#1-4: (4/10-2/12) all BFN

    Surprise Bfp (9/11) - c/p

    DS IUI#1-2 (9/12, 10/12) - BFN

    DS IVF: (11/12) - BFN

    DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN

    FET of 2 day 6 blasts: (12/13) - c/p

    DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.

    FET 5/14: 1 day 5 hatching blast transferred...another BFFN

    Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus

    New RE, additional testing reveals elevated NK Cells

    FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October

     

     

     

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