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What protocol do you have for highish fsh level & older age??

Jill WheatJill Wheat member
in Infertility
We will most likely have a WTF appointment, assuming that our BETA tomorrow is negative, within the next two weeks.  The past two days of HPTS have been suggesting that it will be.  I am wondering what other protocols might be good for us besides the Patch & Microdose Lupron ones.  I have an fsh level of 12.8, am 38 and was producing a relatively low number of eggs with microdose lupron, only 6-12 of them per cycle.  On a higher Gonal F dose one egg took off & the rest were super slow.  I also have had a few miscarriages and chemical pregnancies over the past year which makes us think that egg quality is probably an issue now as I am getting older.

What other protocols might we ask about at our WTF meeting??
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Re: What protocol do you have for highish fsh level & older age??

  • violetmarie61516violetmarie61516 member
    From what I've recently learned, EPP and antagonist might be a better protocol for you.  Lupron sometimes over suppressed ovaries.  Good luck at your WTF!
    TTC #1 Since May 2011 ~ Everyone Welcome
    Me (34): DOR d/t chemo/radiation, Immature Endometrial Lining, Hypothyroidism
    DH (35): MFI d/t testicular torsion and removal, Low T, Oligospermia, Anti-Sperm Antibodies, Currently on T supplements
    Sept '11-April '13 ~  Testing, failed multiple MFI treatments, saving & TONS of praying
    January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN
    February 2014 ~ On to donor embyros ~ 5 blasts!!! 
    March 2014 ~ FET #1 ~ Transferred 2 blasts ~ BFN
    July 2014 ~ Kliman's mock cycle with endometrial function test
    Sample too small for EFT, HE slide showed immature cells
    New protocol planned, saving for another biopsy for EFT
    January 2015 ~ Considering adoption options
    April 2015 ~ Privately arranged adoption of planned pregnancy
    DD#1 ~ Lillyana Violet Marie born 6/15/16, Finalized adoption 12/20/16
    July 13, 2018 ~ BFP....WTF?!?!
    7/16 Beta #1 ~ 466...7/18 Beta #2 ~ 1,077...7/23 Beta #3 ~ 5,291
    7/23 US #1 ~ 1 gestational sac seen and yolk sac
    7/30 US #2 and 1st OB appt ~ 1 perfectly round gestational sac, 1 perfect yolk sac and 1 teeny tiny heart beat seen!!!
    Lilypie Maternity tickers


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  • STBMrsMillerSTBMrsMiller member
    I'm DOR and my protocol last cycle was two weeks of BCP, then stims with high doses of menopur and bravelle, and we used ganirelex to prevent O. I'm not sure what the official name is, but it's a little different than what I see for a lot of others.
    Pregnancy Ticker

    TTC #1 since June 2012
    Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
    DH (29) - MFI low count and morphology

    September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
    October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN

    Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
    Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
    Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
    Results: Cancelled after 11 days of stims due to low response and E2 levels
    Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
    Results: 1 retrieved / 0 mature = Cancelled after ER

    Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
    October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
    May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
    October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
    February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
    Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours

     

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  • herecomesthesunherecomesthesun member
    I have an FSH that has been all over the place. My AFC and AMH levels were fine though. I am on my way to 36.

    STBMrsMiller said:
    my protocol last cycle was two weeks of BCP, then stims with high doses of menopur and bravelle, and we used ganirelex to prevent O. I'm not sure what the official name is, but it's a little different than what I see for a lot of others.
    This sounds a lot like mine, though the doses were mid-level and the bravelle was increased towards the end. and cetrotide was used to prevent O. My ER and fert report were beyond what was expected… ET is in a few days.
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