Anyone else feel like all their friends have disappeared?  I haven't been out with any friends since months before I even had Broderick. Now I'm home all day with 2 under 2 and I never get a break. 
I asked a few friends if they wanted to go have drinks tonight and got the I'm busy or ignored one friend even asked me if I was too tired to go out! Hell yes I'm too tired to out, but I need it. Seems the only people that want to hang with me is my mother in law and my dad. 
I also just had my 6 week appointment got the all clear to do all things physical again and got my birth control. She didn't ask me how I was feeling though and to be honest I'm starting to feel depressed. Don't know if it's just I need to get out or because she was picking at my weight again or the fact that my Brody cries nonstop from tummy issues or what. Oh an Hubby won't even look at or touch me. 
OK whine over....                
                
             
        
Re: Lonely. ...
I think if you are starting to feel depressed, then you really need to talk with someone who is a professional about it. Its better to talk about it and figure things out now then allow them to get worse until you get to a point where you are seriously down.
I'm sorry about your husband, its a transition for them too, and maybe he is going through some things as well. Hopefully things get better in that department too, and I would suggest just being direct with him to see what's up.
as far as your first question, yes, I have lost some friends too and rarely go out anymore. But the good friends will stick around and come see your babies, and you will make more mom friends that understand your life.
remember how precious your babies are, and remind yourself that they are the ones that need you right now, and love on them as much as possible, and whenever you can get a babysitter, try to get a night out - sounds like you need it. Hang in there! We all make sacrifices for our children, because they are worth it.
I think what you are feeling is normal as you try and get a new routine, but that sucks about your friends and your hubby. Have you tried initiating with your hubby? And what about hosting something with your friends?
Eta: god I hope this makes sense... I'm half asleep..
I am pretty darn good at being a lone wolf but I never thought I would have to reappraise the strength of my friendships just because I started a family when most of them swear to never have kids.
I am very thankful for my family that keeps in constant touch with me and for the few mom friends that I have.