Pregnant after IF

When did you stop taking meds?

Yesterday was my last day of baby asprin and progesterone supps. I'm taking my vivelle patches off in about 5 minutes be so I will be all done.  I am kind of excited to be reaching this milestone, but the insane part of me fears that I'm not ready yet .My RE told me before that there's no science at all behind when to stop meds, every RE does it differently, and I've been weaning off of them for the past 2 weeks.
But from what I've read the placenta completely takes over making progesterone and estrogen by week 12, which is 3 days away for me.  So now I'm a little freaked out that I will lose the baby in the next 3 days.  I'm being totally irrational right?  When did you stop meds?

 

IF, 5 losses, 1 son, 1 on the way.
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Re: When did you stop taking meds?

  • I stopped all meds (estrace and PIO/Crinone) at 9 weeks and everything turned out fine!  I understand your worry, I was worried too.  But I think at 12 weeks, you should be okay.

    I am so excited to see you here!  Congrats!
    TTC since December 2011
    Me: 29 ovulatory disorder
    DH: 30 MFI - low everything

    IUI #1: 11/5/12 BFN
    December IUI cancelled due to cyst
    IUI #2: 1/8/13 BFN

    IVF in April 2013 transferred one beautiful blast on 4/13
    Beta #1 4/22: BFP!! 33 Beta #2 54 Beta #3 70 Beta #4 83 Beta #5 105. Possible ectopic, MTX and M/C 5w4d

    FET 6/21 - Beta #1: 79 BFP!! Beta #2: 253 U/S 7/12: saw the sac! U/S #2 7/19 great heartbeat of 127!! U/S #3 heartbeat of 154! U/S #4 graduated to OB

    EDD 3/9/14

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  • I get to stop everything on Saturday at 10 Weeks!!  I am so counting down the days to the last PIO!!!
    ****Siggy Warning****

    IVF Cycle #1 - 4/06/2013 -3dt of 2 embryos, nothing to freeze - BFN 
    IVF Cycle #2 - 7/18/2013- 3dt of 3 embryos.Froze one 3AA 6 Day Blast! - BFN
    IVF Cycle #3 - 9/15/2013 - 3dt of 4 embryos, nothing to freeze - BFP!!!
    10/7 - +HPT - Beta #1 10/10 - 72, Beta#2 10/14 - 518,Harmony 21 @ 12 weeks shows one very healthy little BOY!!


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  • My RE wanted my off at 8 weeks but my obgyn told me if I felt more comfortable I could stay on it til 12 weeks because he rather not have me a crazy mess but not once did my RE or obgyn check my progesterone levels which I found really odd. You'll be fine that baby is a sticker!
  • I stopped at 10 weeks, too, cold turkey which totally worried me. But after a few days I stopped worrying and started enjoying the freedom. :)
    DH & I: 29
    TTC #1 4/2009 -  DD 2/5/10
    TTC #2 since October 2011
    2IF issues
    7/2013 - IUI #1: 50 units Follistim +  Ovidrel  = BFN
    8/2013 - IUI #2: 50 units Follistim +  Ovidrel  = BFP! Beta #1 (12 dpiui) 8/21: 45  Beta #2 (16 dpiui) 8/26: 301 Beta #3 (21 dpiui) 8/30: 1,929. 1st Ultrasound 9/4 - One perfect sac. 2nd Ultrasound 9/13 - Heartbeat at 124 bpm! Anniversary  

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  • Sounds like my RE is one of those overkill ones :P

    I stopped estrace and Vivelle patches by the end of my 9th week, was never told when to stop baby aspirin(I still have no clue!), and I will have my last PIO injection at 12w3d. I am SO looking forward to the last shot next Friday!!!!
    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • I stopped estrace after my last u/s when I was 8w2d.  My last day of PIO will be 11/26, which will be 10 weeks.  I was worried about just stopping cold turkey, and my nurse said if I wanted from like 11/25-11/28 or so I could do 1/2cc if it made me feel better, but by then the placenta should be doing it's job.  I've also heard that the placenta doesn't take over until 12 weeks, so I was concerned about stopping at 10 weeks, but it looks like it's pretty common and the REs are the experts and have done this many many times :-)  I can't wait for no more shots interrupting my evenings!
    Me 31 ~ DH 30
    IVF/FET #1 - BFP!!
    <3 CJW 6/15/2014 <3
    DX - PCOS 2004
    FET #2 - scheduled for 11/24/15
  • I stopped progesterone at 10 weeks. With my DS I was 9 weeks when I stopped. I was terrified both times but turned out fine!
    Me: 33 DH: 36 Unexplained IF
    First pregnancy - DS 01-Apr-09;
    3rd cycle Clomid/IUI after 2 years TTC
    TTC #2 since ~June 2010
    IUI #1 & 2 - Clomid/IUI - BFN
    IUI #3 &4 - Gonal-F/Ovidrel and IUI -- BFN
    IUI #5 - Gonal-F/Ovidrel and IUI -- BFP!!
    EDD: March 22, 2013
    It's triplets!!


  • i stopped my meds @ 10 weeks. don't worry it'll be ok :)

    TTC#2
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  • I stopped meds at 12 weeks. 

    I wouldn't worry about the next 3 days - your placenta is already pumping out progesterone. It's not like a switch that suddenly turns on exactly when you hit 12 weeks - it's a gradual process, and 12 weeks is on the conservative side for estimating when the placenta can completely take over. So try not to worry (I know, it's hard)!
    *** Trigger Warnings ***

    TTC #1 since March 2011
    Dx = Unexplained IF
    1 medicated TI cycle & 4 clomid IUIs = all BFNs
    June 2013 IVF #1 = 6 frosties + BFP!
    DS1 born 2/14

    TTC #2 since December 2014
    May 2015 unassisted BFP ended in m/c at 7wks
    April 2016 FET #1 = BFN
    June 2016 FET #2 = c/p
    August 2016 FET #3 = BFP!
    DS2 born 4/17
  • I was told to stop all meds at week 10, then I come in 3 days later and they test how well my body is doing without them. Apparently the placenta takes over producing what we need around week 9. 
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  • My RE told me I could stop taking Crinone and baby aspirin at week 8.  I stopped the baby aspirin then, but finished up my Crinone (since I had enough left to get through 8wk6d) - my RE said it was my choice whether to finish up the Crinone I had, that by that point the babies were getting everything they needed on their own. 

    I'm like you, though - in the back of my mind I do worry whether I stopped too soon - I'm 9wk2d right now.  I'll have my first OB appt. on Nov. 25th, and another u/s Dec. 3, so I'll feel better after that.

    TTC since July 2011
     
    Me(33): normal HSG; diagnosed with mild PCOS

    DH(35): normal SA
     
    *6 cycles no meds, July-Dec. 2011, all BFN
     
    *Clomid for 3 cycles, Jan-March 2011: BFP March 2011
     
    *MC at 6 weeks

    *2 cycles off
     
    *Started TTC again July 2012 with Clomid, 6 cycles from July-Dec. 2012, all BFN
     
    *1 cycle no meds: BFN
     
    *1 cycle Femara: BFN
     
    *1st RE visit March 2013 - first IUI in April 2013 with Femara, Menopur, and Novarel (BFN); second IUI in May 2013, same protocol (BFN); two cycle break;  third IUI in August 2013, same protocol (BFN)

    *1st IVF cycle, October 2013 (Synarel, Menopur (75 iu), and Gonal-F (150 iu)) -- BFP!!  Saw two babies at our 5wk5d u/s on Oct. 28th!  EDD=June 25, 2014

  • I was on PIO , Endometrin and estrace.... The PIO and estrace stopped at 7 weeks and the Endometin stopped at 11 weeks. I'm technically supposed to stay on my baby aspirin the whole time but most times I forget to take it :( bad I know but I figure the lovenox is there so it's prob ok
    Me: 33, Endocrine issues & FVL       DH: 32, Nothing 
    NTNP 2009-2012         TTC since 2012:
    • Clomid, 2 IUI cycles, and 5 IVF cycles = BFN
    • FET #1   August 2013 = BFP!     EDD 5/11/14
    • Jack dx at 19w1d with Dandy Walker on 12/16/13
    • Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13
    • FET #2 --July 2014  BFP!  ---  EDD  4/5/15

    Jack has handpicked his sibling up there :)

    My blog about IF and loss ... Kate's IF Blog

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  • My timing was about the same.  I started weaning about 9.5 weeks and stopped at 11.5 weeks.  I was nervous too, but my RE said they allowed for lots of overlap, so I think even if the placenta isn't fully functioning, it is making enough that you don't need the meds anymore.  I went back a few days later for labs and ultrasound and everything was great but I was still nervous!
    Married April 2009 
    TTC since May 2010 
    2011 Unexplained IF
    Spring 2012: Tried Clomid x3 with TI, BFN 
     IUI #1 with clomid Sept 2012 BFN 
    IUI #2 with clomid Nov 2012 BFN
    IVF #1 with half ICSI, 2 embryos BFN
    IVF/ICSI #2 May 2013 BFN
    FET Aug 2013  beta #1 247, beta #2 866!!!!!!!

    Due date 5/15/14!!!

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  • I stopped the vivelle & crinone at 8w, pio at 12w, prometrium at 19w3d.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

    Here Comes the Sun Blog
    PAIF/SAIF welcome!
  • I stopped PIO injections cold turkey at 10 weeks. I was nervous too but so far all is well.
    Me 36/DH 46 Me: Low AMH (.21) DOR, mild endo; Started seeing RE 11/12
    Jan-March '13 3 IUIs Clomid + Trigger = BFN
    April '13 IVF 1 MDLF converted to 4th IUI due to 3 runaway follicles! BFN
    July/Aug '13 IVF 1.2 Long Lupron = 7R, 6F, 2T= BFP!!!
    Beta 1=512, Beta 2=1,368 Beta 3= 4,128
    It's a boy!!!!
    SUA, GD
    EDD 4/26/14

    He's Here! Arrived 4/15/14!!!!

    September 2015 - FET with remaining embryos
    Twins! EDD: 6/14/15

    PAIF/SAIF Everyone welcome!
  • Thanks for all the responses ladies!  Makes me feel less nervous!

     

    IF, 5 losses, 1 son, 1 on the way.
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  • You will be fine, no worries! :)

    My RE just said I can stop the PIO/estrace/baby aspirin at 9 1/2 weeks instead of 10 1/2 weeks. My backside thanks him greatly!

  • I stopped all meds at 10w!
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
    image
    PAIF/SAIF/Everyone Welcome! 


  • I was off everything just past 14w but my clinic was very conservative.

    HOORAY FOR YOU! Huge milestone!
    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • I stopped all meds at 10 weeks. Congrats on reaching this milestone!
    My Blog
    Lilypie First Birthday tickers

    TTC #1 since February 2011
    Me: 29 (3/5/13- high NK cells)  DH: 28 (5/8/12- MFI low morph and motility)
    Cycle #21 (IUI#1), Cycle #22 (HSG 9/21/12) and Cycle #23 (IUI#2)=  image
    Cycle #24- December Snow Bunny IVF #1
    ER 12/6/12 (14R, 11M, 9F), ET 12/9/12 transferred 2 day 3 embies
    Bleeding and low betas=very cautious image C/P 5W3D
    Cycle #26 March Lucky Duck- FET #1
    scheduled 3/20/13- CANCELLED- lining issues
    Cycle #27 May Emerald- FET #1.2
    delayed- Starting Trental for 3 months + natural cycles Cycle #28-30=  image
    Cycle #31 August Shooting Star- FET #1.3 
    transferred 1 hatching blast 8/21/13= imageBetas 8/30 (108) and 9/3 (565)

    U/S 9/19/13- HR is 128!  U/S #2 10/4/13- HR is 174!
    It's a BOY!

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