Success after IF

WWSAIFD?

So I really am starting to get frustrated with not getting KU. To TTC#2 I have done 3 clomid/IUI cycles, 2 of which made it to IUI. I did one menopur/clomid but it was cancelled due to no response. I have also done 3 menopur cycles and 2 have made it to IUI. It seems my follicles stop growing after about day 12.

I am thinking about going back to clomid because at least I have a good response and ovulate but then I thought injects had a higher success rate. WWSAIFD? Should I give injects another shot or clomid? 

DS was conceived on the second round of clomid and we are dealing with MFI, low sperm count but DH is on clomid and that has fixed his count in the past but the last few IUIs his count has been low.
Diagnosed MFI- low sperm count  
DS-Born 7/27/11 After 2 years of IF we have our little man
TTC#2 January 2013
11 Medicated cycles gave us
B/G Twins born 10/8/14 @ 32 weeks

Re: WWSAIFD?

  • Yes injects do have a higher rate. Could you try a different inject med with clomid like gonal f? Thats what i used with DS1.
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  • I also would inquire about a different injectable. What about ovidrel?
    TTC since August 2009
    Clomid for 6 cycles starting August 2010- O but no BFP
    SA Septemeber 2010 Looking good 
    HSG September 2010 All clear 
    1st RE visit May 2011 - IUI#1 June 20, 2011: BFN
    IUI #2 July 31 2011: BFP - m/c @ 5w1d
    Surprise BFP on a break cycle 10/4/11, Due June 4, 2012, Born 6/9/2012
    TTC Blog
    TTC#2 : Cycles 1-3 Protocol 1500mg Metformin Daily, Femara + Ovidrel, Progresterone support 
    HSG#2 November 2013 All clear
    Cycle 4 Metformin, Femara, Bravelle, Ovidrel, Progesterone = BFP
    Little Lady Born 8/28/2014
    image

    "There is a design, an alignment, a cry of my heart to see, 
    the beauty of love as it was made to be"
    Mumford & Sons
  • Can you try femara instead of Clomid? You might get a better response. I'm sorry you have not had any luck :( maybe add an hcg trigger for more pinpointed ovulation for IUI.
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    TTC# 1 since 5/10
    Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
    DX: Unexplained IF
    Many IUI's with various meds all BFFN
    IVF #1 11/11 canceled due to OHSS
    IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
    IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
    Healthy baby girl born at 36w4d on 3/9/13

    Baby Birthday Ticker Ticker
    TTC #2
    IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
    Beta 6/18 BFFN

    FET of 2 blasts 7/24...BFP!
    Healthy baby girl born at 36w3d on 3/17/15

    TTC#3
    IVF #5 June 2018- PGS planned, no surviving embryos
    IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
    IVF #7 August 2019-....?
  • Thanks ladies. I'll ask about gonal f and ovidrel. Kmc I am using a trigger as well but I think I'll ask about femara too. I think the RE and I need to do some more brainstorming.
    Diagnosed MFI- low sperm count  
    DS-Born 7/27/11 After 2 years of IF we have our little man
    TTC#2 January 2013
    11 Medicated cycles gave us
    B/G Twins born 10/8/14 @ 32 weeks
  • My RE said that injects produce better quality eggs, for what it's worth.  Injects are the more aggressive route, I wouldn't go back to clomid.

    ___________________________________________________________________________

    Trying for #1 since May 2010   l   DX ~ Unexplained Infertility June 2011

    IUI #1&2 = BFN; IUI #3 = BFP, m/c @ 6 weeks

    November '11 ~ IVF#1 ~ ER 11/18 (29R, 17F) ~ 5dt of one beautiful blast on 11/23 = BFP!!

    Beta #1 9dp5dt = 116, P4 = 28 ~ Beta #2 13dp5dt = 700 ~ Beta #3 20dp5dt = 9500, P4 = 26

    1st u/s 12/27 - hb of 156!! EDD 8.10.12 :)   **TEAM GREEN!**

    Sweet baby boy born 8.18.12

    Baby Birthday Ticker Ticker

    Trying for #2

    FET #1 - October '13 - c/p   l   FET #2 - December '13 - cancelled :(   l   FET #2.2 - 1.30.14 - BFN

    ~ More testing - hysteroscopy, endometrial biopsy & more b/w - all normal / negative~

    Surprise BFP while waiting on FET #3 ~ beta #1 500; beta #2 1600; first u/s 4/3 - measuring 5w5d, no hb yet!; 2nd u/s 4/10 - hb 132, measuring 6w6d - EDD 11.29.14 :)    **TEAM GREEN!**

    Beautiful baby girl born 11.24.14

      Baby Birthday Ticker Ticker

  • I would second asking about femara. It worked for me. GL, I know this is frustrating. Hugs.
    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
     image
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  • Also, I believe Clomid has a 6 cycle limit and it looks like you have already done 5. I would definitely not do another round of Clomid.
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    TTC# 1 since 5/10
    Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
    DX: Unexplained IF
    Many IUI's with various meds all BFFN
    IVF #1 11/11 canceled due to OHSS
    IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
    IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
    Healthy baby girl born at 36w4d on 3/9/13

    Baby Birthday Ticker Ticker
    TTC #2
    IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
    Beta 6/18 BFFN

    FET of 2 blasts 7/24...BFP!
    Healthy baby girl born at 36w3d on 3/17/15

    TTC#3
    IVF #5 June 2018- PGS planned, no surviving embryos
    IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
    IVF #7 August 2019-....?
  • Ok so I have been googling and it looks like Ovirdrel is used as a trigger. But I remember reading about someone using Follitism in their siggy so I googled that one and I think that may be the way to go. I haven't gotten AF yet so Im waiting to schedule my CD3 appt. 

    Anyone have any good/bad experiences with Follitism? 
    Diagnosed MFI- low sperm count  
    DS-Born 7/27/11 After 2 years of IF we have our little man
    TTC#2 January 2013
    11 Medicated cycles gave us
    B/G Twins born 10/8/14 @ 32 weeks
  • Compared to Clomid, Follistim was a breeze for me! 

    ___________________________________________________________________________

    Trying for #1 since May 2010   l   DX ~ Unexplained Infertility June 2011

    IUI #1&2 = BFN; IUI #3 = BFP, m/c @ 6 weeks

    November '11 ~ IVF#1 ~ ER 11/18 (29R, 17F) ~ 5dt of one beautiful blast on 11/23 = BFP!!

    Beta #1 9dp5dt = 116, P4 = 28 ~ Beta #2 13dp5dt = 700 ~ Beta #3 20dp5dt = 9500, P4 = 26

    1st u/s 12/27 - hb of 156!! EDD 8.10.12 :)   **TEAM GREEN!**

    Sweet baby boy born 8.18.12

    Baby Birthday Ticker Ticker

    Trying for #2

    FET #1 - October '13 - c/p   l   FET #2 - December '13 - cancelled :(   l   FET #2.2 - 1.30.14 - BFN

    ~ More testing - hysteroscopy, endometrial biopsy & more b/w - all normal / negative~

    Surprise BFP while waiting on FET #3 ~ beta #1 500; beta #2 1600; first u/s 4/3 - measuring 5w5d, no hb yet!; 2nd u/s 4/10 - hb 132, measuring 6w6d - EDD 11.29.14 :)    **TEAM GREEN!**

    Beautiful baby girl born 11.24.14

      Baby Birthday Ticker Ticker

  • I used Follistim in 8/12 of my cycles. It's a total breeze and the injection pen is super easy to use. I also used Ovidrel triggers for all of my IUI cycles (I used Pregnyl for my IVF retrivals). No problems with either one.
    TTC in 2009, Dx: Unexplained IF
    Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
    12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
    Our perfect baby boys were born at 36w1d!! 








  • I think this may be the way to go. I am hoping the clinic I go to uses this drug and that its covered by my insurance. I read that its pretty expensive because there is still a patent on it. But for the future the patent expires in 2015.
    Diagnosed MFI- low sperm count  
    DS-Born 7/27/11 After 2 years of IF we have our little man
    TTC#2 January 2013
    11 Medicated cycles gave us
    B/G Twins born 10/8/14 @ 32 weeks
  • I agree with trying injects as opposed to going back to Clomid. We used Follistim for three IUI's total, one time for G and two times so far for baby #2. 
    Dx: Unexplained Infertility

    TTC #1 
    IUI's #1 - #3 Clomid = BFN's, IUI #4 Follistim = BFP
    Grayson arrived via emergency c-section on 7/28/12!

    TTC #2 
    IUI's #1 - #4 Follistim = BFN's
    IVF #1 w/ ICSI + PGS: Lupron/Follistim/Menopur
    ER 4/13 - 19R, 13F, 4 PGS tested embryos, 1 normal
    5/14 FET: BFP. Beta #1: 123, Beta #2: 327, Beta #3: 854
    Cora arrived 1/23/15 via RCS!
  • I agree with trying injects as opposed to going back to Clomid. We used Follistim for three IUI's total, one time for G and two times so far for baby #2. 
    I think it was your siggy that i remembered seeing Follitism used in. I am def going to ask about it.
    Diagnosed MFI- low sperm count  
    DS-Born 7/27/11 After 2 years of IF we have our little man
    TTC#2 January 2013
    11 Medicated cycles gave us
    B/G Twins born 10/8/14 @ 32 weeks
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