Third-Party Reproduction

It didn't work

I can't believe it didn't work. We had a 70% chance and yet again we fell on the bad side of the odds.

We have 2 frosties from this cycle, but the success rate at my clinic is half of what it is with a fresh cycle.
I'm not optimistic, but I'm relieved.

It made the decision for us as to what our next steps will be. I don't know where we go if this FET doesn't work either.

Neither of us WANT to keep trying. This is all so painful and disappointing, but we have agreed the alternative is far worse.

Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI   (TTC#1 since 2009)

IVFs#1-4: (4/10-2/12) all BFN

Surprise Bfp (9/11) - c/p

DS IUI#1-2 (9/12, 10/12) - BFN

DS IVF: (11/12) - BFN

DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN

FET of 2 day 6 blasts: (12/13) - c/p

DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.

FET 5/14: 1 day 5 hatching blast transferred...another BFFN

Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus

New RE, additional testing reveals elevated NK Cells

FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October

 

 

 

Re: It didn't work

  • Oh KM, I am so so sorry. It's so unfair. Take good care of yourself.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

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  • I am so sorry, sweetie.  DE failures are especially cruel, I think.
  • Giant hugs. I am so sorry this happened. :( 

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Oh no no no KM :-( hugs and take care of yourself.

    April 2013 DE IVF= BFN

    September 2013 DE IVF (Fingers Crossed) = BFFFN! again...

    October 2013 FET of our last 2 = Beta Hellzz for 6-7 Weeks. M/C

  • I'm so sorry to hear this.  I will keep you in my thoughts.
  • Big hugs KM. I am so very sorry :(

    ME:46 MH:44 DE IVF 2014
    Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive.  Waiting for another donor. Donor picked!! (1/18/14)

    DE IVF #1 (4/26) BFN  DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!


     

     

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  • Oh KM, my heart hurts to hear this update.  =((

    I am so very sorry....huge (((HUGS))) to you!!

    I can certainly relate to how you're feeling about your next FET, but I will keep you in my T&P's.

    Me: AMA, DOR, undetectable AMH, carrier of SMA, MTHFR homozygous C677T, high cytokines, low IGg B cells, Factor XIII V34l mutation, High Anti-Phosphatidylethanolmine, borderline hypothyroid and mildly insulin resistant.

     

    MH: No known issues, aside from MTHFR.

     

    Recommendations from RI: LIT, Humira, IVIG, Lovenox, Baby Aspirin, Folic Acid, Low-dose synthroid and Metformin.

     

    Currently taking:  Pre-Natal vitamins, Foltanx, Low-dose synthroid and Metformin. 

     

    When cycling also taking: Baby Aspirin, Lovenox, Humira and IVIG.

     

    TTC since 7/11/09..with medical intervention starting in 2010, including 4 failed IVF's and 6 failed IUI's...only "success" was a chemical pregnancy in 11/2012 (credited to use of DE).

    FET #1 (11th cycle) on 8/23/13 = BFN.

    FET #2 (12th cycle) Transfer of last two (day 6) donor egg blasts on 1/22/14 = BFP, EDD = 10/10/14 (please stick little BOY!)

     

    My favorite breed:

     

    image

    ***PAIF/SAIF always welcome***

  • huge hugs. it is brutal, there is no better description.
    take special care.
    TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own, autoimmune disease 3 Failed IUI's (2/2012, 4/2012, 6/2012) 
    IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d
    FET #1 December 2012, BFN
    FET #2 February 2013, no embies survived thaw
    IVF #2, BFP #2, Loss #2 March 2013, Scar tissue discovered, RPL testing,
    IVF #3, BFP #3, Loss #3 (twins) September 2013
    Hostile ute, moving onto Gestational Carrier!

    GC/FET #1 of 1 5AA blast and 1 compacted blast, February 2014, BFP #4 on 3/1/2014!
    6w u/s 1 bean with h/b of 145 bpm, 8w u/s 187 bpm
    EDD 11/7/14. Please, please, please stick little one!

    Praying unceasingly for a miracle. ALL welcome!

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  • I am so sorry, sending you a big hug. I know how much this process sucks!! 
    Me- Ok as 1/13
    DH- Azoospermia diagnosis
    DIUI #1 7/13 BFN
    DIUI #2 8/31/13 BFN
    DIUI #3 10/26/13 Fingers crossed!




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  • Yes, DE BFN's are pretty much the worst thing ever.  I am so, so sorry you are going through this.  (((HUGS)))
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

    Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker
  • Km, I'm really sorry your cycle didn't work out.  Hugs to you!

    9/15/14 - Our first son born thanks to donor eggs at RBA after 7 failed own egg IVF cycles.
  • Huge hugs. I'm so sorry.

    imageimageimage
    Lilypie First Birthday tickers
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