Question from IF - re: embryos that made it to blast

katekat8721 · October 2013

Hi girls!

Question for you from an IF lurker

...

If you did IVF and were able to culture out to day 5, how many embryos did you have originally and how many of those made it to blasts? Out of those blasts, how many made it to freeze?

Hope that makes sense. I've been on Dr. Google (bad, I know) and it looks like about 30% make it to blast from embryo stage. I was just wondering what your experience was. Thanks for your insight!

Crystal120410 · October 2013

Every cycle with every person is going to be different.
Ivf#1 6r5f ET1 froze 3
Ivf#2 10r8f ET2 froze 0

PhillyJ33 · October 2013

I had 7 retrieved, 6 fertilized with ICSI and 4 made it to blast. I transferred 2 and froze 2.

Keephope2012 · October 2013

I had 14 retrieved, 13 mature, 11 fertilized. I believe there were 7 on day 5 still growing. I transferred one and had 4 to freeze. Good luck!

GermanGirl2007 · October 2013

I had 4 retrieved, 2 made it to blast and were frozen (w/vitrification) and the one that was thawed continued to grow and was transferred as a hatching blast which resulted in my BFP. The other is still frozen.

VegasGal1978 · October 2013

18 retrieved, 13 fertilized, 4 to day-5 blast, 2 frozen. Currently 33w with first SET of one day-5 blast.

Gr8te · October 2013

I think it's average to lose about half. We lost 11 out of 15 between day 4-5 because of DNA sperm fragmentation. My RE considered the loss significant and we had almost 27% survive. GL

Roeni · October 2013

10 fertilized and 6 made it to blast

ThereBeDragons · October 2013

It varies- even with the same patient and the same treatment.

Our first IVF we had 12 retrieved, 9fert: 2 d5 blasts fresh and 3 d5 frozen (2 morulas).
Second had 11 retrieved, 8 fert: 2 d5 blasts fresh and 3 frozen (all highest quality blasts).
Third had 14 retrieved, 12 fert: (no fresh transfer) but only 2 d5 blasts made it to freeze.

Our worst retrieval/fert numbers resulted in the highest number of high quality embryos.
Our best numbers- the lowest.

In the end it doesn't really matter though- you only need one good embryo to make a baby.

curlylocks3 · October 2013

We had 6 fertilized and 3 made it to freeze (we didn't transfer any).

monimu13 · October 2013

9R, 7M, 4F, only 2 made it to blast on day 5 and we didn't have any left to freeze as we transferred both.

kflynn81 · October 2013

IVF #1- 19R, 11M, 7F--- 0 frozen

IVF#2- 11R, 7M, 5F---0 frozen

IVF #3- 19R, 11M, 8F---0 frozen

IVF #4- 45R, 33M, 26F-- 7 frozen (baby is from FET #1 following this cycle)

So basically I guess my only cycle with frozen embies was 15% of the number retrieved, 21% of those that were mature and 27% of those that fertilized. It was/is suspected that I have an egg quality issue I'm assuming I was only able to get those to freeze due to the large number I had to work with....but thats just me of course

zazu13 · October 2013

For this cycle ( our best of 4) we had exactly 30% - 3/10 embryos were blasts on day 5. We transferred two and froze one. Our previous cycle at this lab was 2/6 so also close to 30%. A lot depends on your lab but the potential of your embryos is heavily dependent on egg & sperm quality.

DebateThis · October 2013

25 retrieved
24 mature
12 ICSI'ed/12 traditional fertilization
11 of the ICSI group fertilized, 11 of the traditional group fertilized (so 22 total fertilized)
15 made it to blasts
1 for SET
4 didn't make it to freeze
10 went in the freezer

xladybassx · October 2013

We had 15 retrieved, and of that 10 were mature. Only 4 fertilized and by day 3 one of them didn't make it, one of them was 6 cells, and two were 8 cells. We transferred the two 8 cell embies and left the six cell to culture. It did not make it to blast/freeze stage. I'm not sure if either of the 8 cell embies would have made it to freeze or not since we decided to transfer them both on day 3.

golfrgal · October 2013

7 retrieved, all fertilized w/ICSI, 4 made it to blast for CCS testing, 2 viable and frozen due to OHSS, SET 1 and saved the other for possible sibling.

htn1763 · October 2013

I had 4 mature and fertilize and 4 make it to blasts.

We put in 1 and 2 made it to freeze.

So we only lost 1 between blast and freeze.

auntjessy · October 2013

15R, 13M, 9F, 4 made it to blast. Transferred 2, froze 2. Expecting twins.

BzeetyD · October 2013

Despite what you see here, having blasts to freeze isn't super common. Maybe 1/3 to maybe 1/2 of women have frozens after an ER. I've been in many support groups and SO many couples do not have frozens. It's really best to not expect it to happen or you'll be crushed.

Also, you're asking on a board of women who have had success, many on their 1st IVF, so it might be better to ask on the IF board, where there's a more varied experience and you'd get a more balanced response.

I totally realize I'm an outlier on this board and our story is an "extreme" on but certainly I am someone with a lot of IVF experience.

Out of 91 eggs retrieved over 4 IVFs, we didn't have any blasts to freeze until we did IVF#4.
And then we had 6. Out of those 3 were normal. PG with 1 now and 2 frozen. Truth.