Community› The Bump Message Boards› Pregnant after 35
Pregnant after 35
New Discussion

conflicting test results; overwhelmed

dglvrk2dglvrk2 member
in Pregnant after 35
I'm almost 18 weeks pregnant.  I had the non-invasive prenatal test (NIPT) in July.  It came up negative for chromosomal abnormalities it screens for, including Down Syndrome (trisomy 21). Specifically, my chances of having a baby with DS according to this test is 1/10,000.  I had a blood test at 16 weeks as part of serum integrated screening too.  It's free in CA (I live in San Francisco) and also screens for neural tube deficiencies.  I got the results earlier this week.  It's positive for Down Syndrome; noting my risk for having a baby with DS is 1/13.  I know both of these are screenings, not diagnostic tests and that the NIPT is apparently MUCH more reliable then the serum integrated screening. Nevertheless, it's confusing. Should I completely rely on the NIPT and assume my baby is free of the chromosomal abnormalities it screens for?  Or proceed with an amnio?   I really do want to know if I have a baby with DS; primarily to prepare for him/her as best as possible.  I'm just confused......my emotions change every few minutes.  Do I just trust the NIPT or proceed with an amnio?  Thoughts?  

Visit The Nest! image image
<a href="http://www.thebump.com/?utm_source=ticker&utm_medium=HTML&utm_campaign=tickers" title="Parenting Tips"><img src="http://global.thebump.com/tickers/tt1761a3.aspx" alt=" BabyFruit Ticker" border="0"  /></a>
Report Reply to Post

Re: conflicting test results; overwhelmed

  • RNmommyof2RNmommyof2 member
    The only way to know for certain is to get an amnio. I think if I were in  your shoes, that's what I would do.
    image


    Report Reply
  • Loading the player...
  • LucyRicardo3LucyRicardo3 member
    I would tend to go with the NIPT results. But it's easier to say that when I'm on this side of the thread.
    From what I've been told by my dr's the false positive rates of the standard screening are far more frequent that incorrect NIPT results because the NIPT is reviewing the actual fetal DNA.
    It would be a tough call. In my humble opinion, the minute risks of amnio outweigh my choice of going that route. I would, however, have to deliver at a different (more specialized) hospital a little further away, rather than my local small-town hospital so we would have access to whatever specialists might be needed at delivery.
    Hugs and best wishes on your decision....

    Lilypie Kids Birthday tickers  image


    Lilypie - (9CKY)Lilypie - (xzY1)





    Report Reply
  • happywifemomofonehappywifemomofone member

    Hi-I also screened + for Down's.  We had a Level II u/s.  When there were no hard or soft markers for Down's, we decided NOT to proceed with the amnio.  Had there been markers for Down's, we would not have hesitated with the amnio, so that we could educate ourselves and assemble the very best medical team to deal with any issues that might arise.  GL!!, these decisions are hard!!

     

    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
    Report Reply
  • GuennieGuennie member
    Has your dr not suggested a level 2 ultrasound? I would opt for one before jumping to an amnio, especially since you screened negative with the more reliable test. I screened positive for Downs also and like happywife I had a level 2 ultrasound to check for markers. Everything looked perfect. If you feel you need further reassurance this is what I would ask for.
    Me:41, DH:41 Positive for MTHFR mutations- one copy C677T, one copy A1298C. One daughter born on Thanksgiving in 2013. Six losses.
    Report Reply
  • SurpriseAt39SurpriseAt39 member
    I would definitely get your doctor's thoughts/opinions on this. 
    As well, an ultrasound should be done. 
    (My doc orders ultrasound and bloodwork at same time to get truer results for screening)


    Report Reply
  • jeffraejeffrae member
    With dd1, we had 1/8 result for trisomy 18. We did level two u/s and no markers were found. We opted to not have the amino. With dd2, we skipped all screening based on our "false positive"
    Warning No formatter is installed for the format bbhtml
    Report Reply
This discussion has been closed.
Choose Another Board
Search Boards
"
"