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IUI - quick timing and HCG questions

JzylaJzyla member
in Trouble TTC
We're going through with IUI#3 this cycle using clomid again, since there is a wait list for injectables where I am (they 'batch' the groups - meaning they need to put a number of clients on BC and then start them all at the same time and I missed the deadline). Annnnyways... here are my questions:

How many hours does your RE wait between HCG and IUI? Our first 2 were only 26 hours from trigger to IUI and I really felt like that was too soon. We will be getting our next IUI from a satellite clinic that's more experienced, and they do more like 36 hours. Just curious about others' timing.

My HCG prescription comes for double the dose I need (1000) so I used half of it and was told to save the other half (it's all mixed) for the 'next' IUI, if there was one. We were told it would be fine as long as it was refrigerated, but we had to stay overnight at a hotel that didn't have a fridge, so it went for the first 24-30 hours after the injection without being refrigerated. So should I cut my losses and pay for a new prescription or is it still usable? 
30 yrs, healthy & TTC since April 2010 
DH 32yrs & healthy
*unexplained infertility* 

Regularly access alternative medicine to supplement a lack of resources in our geographical area.
  • Three rounds of clomid (50mg days 3-7) were useless.
  • IUI#1 w/clomid & HCG in May 2013, BFN.
  • IUI#2 w/clomid & HCG on July 23rd. BFN.
  • IUI #3 in August cancelled last minute, due to lab error.
  • IVF#1 - Started Gonal F stims October 13 2013 for IUI. Over-responded with too many follicles, so converted to IVF. Retrieval October 29th - got 5 eggs, 4 fertilized. Had 2 perfect little embryos transferred on day 3 (Nov. 1). The remaining 2 didn't survive to freeze. Got our BFN on November 13th 2013.
  • IVF#2 - Started stims August 21st. Triggered with Suprefact, started on dostinex due to risk of OHSS. Retrieval September 5th - got 27 eggs! 21 embryos on day 3. Embryos deteriorated quickly. ESet 5day blast on Sept 10. No embryos high enough quality to freeze. BFN came Sept. 22.

Reserved a semi-known proven donor in August .

Waiting for consult/screening and protocols with estimated fresh cycle timing in October



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Re: IUI - quick timing and HCG questions

  • ErinSaysErinSays member
    My clinic gave me a 6-hour window to trigger in, with the IUI scheduled 35-41 hours later. I opted to trigger at the latest time given to cut the wait time to 35 hours.

    No idea on the meds! I would call a pharmacist to be sure. How warm did the room get?
    Me (34) & DH (45) - NTNP since June 2011
    RE: 12/1/12 - Me: PCOS; DH: Low T
    2/13: DH's T went from 190 to 777!
    Cycle 1 1/25/13: Clomid 100mg + Trigger + TI + Progesterone = Ectopic pregnancy
    3/7/13: MTX injections put me on the bench.
    Cycle 2 6/7/13: Clomid 100mg CD3-7 = No response
    Cycle 2.1 Clomid 150mg CD 19-23 + Trigger + TI + Progesterone = BFN
    Cycle 3 7/21/13: Clomid 150mg + Trigger + IUI #1 + Progesterone = BFN
    Cycle 4 8/25/13: Bravelle 75-112iu + Trigger + IUI #2 + Progesterone = BFN
    Cycle 5 9/23/13: Bravelle 75-225iu + Trigger + IUI #3 + Progesterone = BFFN
    Onto IVF - starting injects on Christmas Day

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  • JzylaJzyla member
    Hmm... I think the room was just like 'room temp' - maybe 72 degrees. Silly me, I never thought to call the pharmacist. Good idea. Meds seem to be way more expensive in Canada, considering what I have read about what other people say on here. I was just hoping to save a little money, but not at the expense of our success.

    I figured that 26 hours was way too early. Especially since DH's swimmers apparently die slightly prematurely, and then washed, they would die even faster. I'm hoping 36 is closer to the magic number.
    30 yrs, healthy & TTC since April 2010 
    DH 32yrs & healthy
    *unexplained infertility* 

    Regularly access alternative medicine to supplement a lack of resources in our geographical area.
    • Three rounds of clomid (50mg days 3-7) were useless.
    • IUI#1 w/clomid & HCG in May 2013, BFN.
    • IUI#2 w/clomid & HCG on July 23rd. BFN.
    • IUI #3 in August cancelled last minute, due to lab error.
    • IVF#1 - Started Gonal F stims October 13 2013 for IUI. Over-responded with too many follicles, so converted to IVF. Retrieval October 29th - got 5 eggs, 4 fertilized. Had 2 perfect little embryos transferred on day 3 (Nov. 1). The remaining 2 didn't survive to freeze. Got our BFN on November 13th 2013.
    • IVF#2 - Started stims August 21st. Triggered with Suprefact, started on dostinex due to risk of OHSS. Retrieval September 5th - got 27 eggs! 21 embryos on day 3. Embryos deteriorated quickly. ESet 5day blast on Sept 10. No embryos high enough quality to freeze. BFN came Sept. 22.

    Reserved a semi-known proven donor in August .

    Waiting for consult/screening and protocols with estimated fresh cycle timing in October



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  • RunCC37RunCC37 member
    We've always triggered 36 hours before the IUI and did TI the night of trigger & IUI. Hasn't worked for us yet.

    About the spoiled meds... I'd call my RE to check, but I'd personally not be able to trust it. I wouldn't want to worry about it for the whole cycle, and if I got a BFN out of the deal, I would agonize over it.
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
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  • KendraL86KendraL86 member
    My RE recommends an IUI 26 hours after trigger. What was the reason they gave for only using half the HCG med? I was told to use all 10,000.

    It's amazing the differences in protocol for different clinics.
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  • MrsSJE2011MrsSJE2011
    I second to call the pharmacist.  Also, all my triggers were at exactly 36 hours.  I am really not sure the lifespan on washed sperm to know if 26 was too early.  I am pretty sure unwashed is 24 hours and that it would be shorter for washed.
    Married: 7/2/11 TTC: 12/2011
    Me: 31, PCOS DH: 37, low morph and low counts

    4 medicated TI, 1 IUI+Femara, 1 IUI+GonalF = BFNs
    IVF #1 Lupron/GonalF (Dec 2012)= 30R, 21M, 21F with ICSI, 18 HIP frosties!!!
    FET in August 2013 

    http://i45.tinypic.com/21pym9.jpg

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