Infertility

CD 10 Monitoring

Hey ladies - So I'm on CD10 of my natural frozen embryo transfer. I posted this in the fireflies check-in, but it was five pages deep so I thought I would get your feedback here. Yesterday was an early monitoring, because I haven't ovulated or even had an LH surge on a digital OPK. Here were my stats: 

Lining: 4.6

Follicles: 2 follicles naturally grown, each around 10mm, one will likely take the lead soon 

E2: 65

LH: Elevated (which is okay, right? since I"m getting closer to ovulating?) 

Can someone give me some feedback on how I'm doing? I'm really worried because the lining sounds so thin...will it really build up enough in the next 8-10 days?  

| Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
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PAIF/SAIF/Everyone Welcome! 


Re: CD 10 Monitoring

  • I haven't done a natural cycle before but I wanted to wish you good luck!!! I usually start amedicated cycle around 4 something.  I think 8-10 days is enough time for the lining to thicken up and become triple layer.   When do you go back for your next monitored appt? 

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


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  • I also wanted to add that I saw my naturopath who is really great with fertility, and I saw her right after my monitoring. She gave me a few new supplements and I wanted to share: Shatavari root powder (I take a shot of it dissolved in warm water, 1 tsp to a shot of warm water 1x/each day) and also another natural supplement. She said this should really help with lining. She also has me starting up at the acupuncturist next week. Fingers crossed it helps! 
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
    image
    PAIF/SAIF/Everyone Welcome! 


  • imageBrideJackie11:
    I haven't done a natural cycle before but I wanted to wish you good luck!!! I usually start amedicated cycle around 4 something.  I think 8-10 days is enough time for the lining to thicken up and become triple layer.   When do you go back for your next monitored appt? 
     

    Thank you so much, Jackie - I'm headed back for more monitoring on Sunday morning...so another four days. I'll update then for sure. Hopefully the stuff my naturopath gave me will help, because it sure tastes awful. :)  

    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
    image
    PAIF/SAIF/Everyone Welcome! 


  • imagegeordie314:
    I done lots of reading last night about lining!
    I read that it should grow 1 to 2 mm every other day.
    I hope the stuff you were given helps. I did respond on the fireflies check in and ask if you would consider taking e2v if you needed it to help.
    Let us know how it goes on Sunday!


    What is e2v? Thanks, Geordie!
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
    image
    PAIF/SAIF/Everyone Welcome! 


  • As you get closer to ovulating and your e2 rises, your lining will thicken up quickly.  I think your lining looks fine for follies that are so small still.  Your e2 also looks fine for that size follicle.  When you say your LH is elevated, how elevated are you talking?

    What does your clinic say?  That's what I would be using a basis for how well you're doing. Are you generally a late ovulator? 

     
    me 33/DH 36
    ttc since 10/2008; d/x: mild MFI, stageII endo
    ~~PAIF/SAIF Welcome~~
    11 IUI’s = 1 m/c (7w4d)
    IVF#1 January 2012 BFN, FET #1 April 2012 BFN
    Surprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)
    IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762
    U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160
    Stick Frogger Stick! Please!!!!!!!!!!!!!   It's a Girl, EDD April 7, 2014

    BabyFruit Ticker

  • I don't know much about your lining question but I just wanted to say how happy I am for you that you have started your cycle!! I'll be rooting for you!!!!

    Married my best friend on 9.6.11 
    Me 31 DH 29 
    TTC since 12/2011 
    Me - all normal test results 
    DH - SA #1, #2 and #3 - 0% morphology 
    Straight to IVF w/ ICSI 
    April 3 - start date for BC 
    April 18 - tentative start date for injections 
    Tentative IVF dates: ER - 4/27 and ET - 5/3!! DELAYED.
    IVF #1 - May 6 - Estrace
    May 17 - started injections!
    ER and ET end of May!! BFFN :(
    FET #1 - June 28th - BFP!!!! :)
    Beta #1 - 164, Beta #2 - 381
    1st u/s 7/16/13 - 2 sacs with yolks! 1 smaller than the other - Possible Twins?! 
    2nd u/s 7/26/13 - 1 healthy baby with heartbeat of 123bpm! Second sac empty. Next u/s 8/5/13.
    8/5/13 (7w2d) - no heartbeat. Lost our precious LO :-/
    D&C on 8/12/13 - finally neg hcg 2 months later on 10/3/13.
    Saline Songram on 10/10/13 - found polyp :-( post-poned again.
    Hysteroscopy on 10/29/13.
    FET #2 - BFP!!!! :-) 
    Beta #1 - 265, Beta #2 - 692
    12/24-12/28 (6w) - lost our LO (2nd miscarriage in a row)
    RPL panel and Karyotyping; results all normal!
    Started bcp's 1/24/14; saline sonogram 1/30/14 - All clear!!
    IVF #2 02/15/14; ER 02/26/14 - freeze all due to mild OHSS. 
    7 blasts; PGD on all 7 - all 7 normal!!!
    FET #3 4/8/14; BFP!! :-)
    Beta #1 - 235, Beta #2 - 539
    1st u/s - It's TWINS!!!!
    2nd u/s- both babies measuring on track! Heartbeats of 118 and 122!!
    EDD: Christmas Day!!!

    ** ALL ARE WELCOMED **

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    image  photo 866da40f5178fed79efe23fc8a4e8a_zps4498a9cc.jpgimage 
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