Well folks, my period has arrived again. We now have 4 unsuccessful IUIs under our belts. Part of me wants to plow ahead full steam with another medicated IUI cycle, part of me wants to get off the meds and try another natural cycle, and part of me wants to take a month or two off... My wife an I are equally conflicted as to next steps. I have a call into the dr to see what she thinks....
What say you wonderful ladies? Any advice?
Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012
5 medicated IUIs w/ RE (March - July 2013) = BFN
Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer! *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581 *********William George born June 4, 2014*********
Re: To take a break or not, that is the question...
Nuts
I'm so sorry to hear that, KH! I haven't even had my first IUI yet so I don't know if I'm qualified to give you advice, but I thought I'd throw my 2 cents in for what it's worth.
My OBGYN told me it usually takes 3-6 tries. You've tried 4 times, so you still have 2 more before doctors might think you have a deeper problem. I've done the research, and I know how much it costs to keep trying... so I know that may not be very comforting. If you're emotionally drained and exhausted by the process, maybe it wouldn't hurt to take a month off. I heard accupuncture helps a lot (I'm going to make an appointment for that myself!) and maybe taking time to relax, do something fun, and take your mind off of it will refresh your spirit and help you with your next round
Hang in there! It will happen - just a matter of time.
I'm so sorry about your BFN this cylce.
Obviously this is your choice and any of the options you've mentioned are perfectly good ones.
We took a one cycle break after two IUIs because the stress of cycle monitoring and the TWW and the BFNs was really getting to us. It was lovely. I'm so glad we did it. We came back to the third IUI feeling ready to get started again. (To be honest, the clinic quickly got the best of us and it felt like our break hadn't even happened soon after we started again, but I'm so glad that we did take it.)
Are there things you could do or enjoy this summer if you do a cycle or two off? If so, it might be worth it to rejuvenate, re-evaluate, and reconnect.
Good luck with whatever you choose.
We're queer. I'm 33, have severe stage 4 endo, and had both fallopian tubes removed. My love ("Manada" on the boards, 32) was diagnosed with diminished ovarian reserve. We did Partner IVF (my eggs, her uterus). We lost our twins Tavin and Casey at 21 weeks gestation.
Our IUIs
with @Manada: IUI# 1-7 (December 2012- September 2013) all BFN. Tried natural, femara, clomid, puregon/follistim, clomid and menopur combo, both the ovidrel and HCG triggers.
Our IVFs:
IVF #1 my eggs November/December 2013: Cancelled IVF due to poor response
IVF #2 my eggs/Manada's uterus January/February 2014
BCPs and lupron overlap Stimmed: 1/22-2/2: Bravelle and Menopur (dosage ranged from B300 and M150 to B375 and M150 to B300 and M225)
2/4 retrieved 10 eggs. Endo was much worse than expected. Only 3 eggs fertilized; February 7 transferred two day 3 embryos, froze one. All great condition.
BFP eve of 6dp3dt; Beta 1 (11dp3dt): 110; Beta 2 (13dp3dt): 175; Beta 3 (15dp3dt): 348; Beta 4 (19dp3dt): 2222; Beta 5 (21dp3dt): 4255
1st ultrasound (3/6 6w 1d): TWINS!!!! Twin A measuring 6w1d with a heartbeat of 118bpm. Twin B measuring 6w0d with a heartbeat of 113bpm.
***July 18, 2014 we lost our beautiful babies at 21 weeks gestation. They were born too early. Tavin Sara T. and Casey Elizabeth T. are beautiful and precious and we will love them and miss them forever.***
FET #1 December 2014
Married to M and proud mothers to Olivia and Elise (8/19/2014) and to our fur-babies: Capone (pitbull), Jax and Atticus (cats)
I'm so sorry to hear this, that disappointment is awful. I don't know if I could give direct advice, but I can tell you what we did and why because we considered the same thing. After three failed iui's we were both feeling really stressed and upset. We considered taking the next month off, especially because there were some extra hoops to jump through that month with TTC. My wife did not want to take a month off so we compromised and said we would really focus on being relaxed, changing our mind-set, and trying some new coping strategies (going out more, not focusing on TTC, etc...) and if we started to feel better, we would do an iui that month. It turned out that we both felt better in a few weeks AND her ovulation was a week late which gave us some extra time so we went ahead and did it. That was actually the month we got pregnant. I think being more relaxed was really important for us (not necessarily to get a BFP, but just to feel happier overall). If that would have required a month off to get to that place, then we would have done that.
I wish you peace in whatever decision you guys make
Thanks,everyone. I appreciate your thoughts/insights.
After a long discussion, I think my wife and I have decided to go ahead with another medicated cycle this month and do back-to-back IUIs with the two remaining vials of sperm that we have left. And we are going to talk to our Dr about triggering later, since we fear that we are not allowing my follicles enough time before we trigger.
CD12 is on a Sunday for me this cycle, so we will do a CD13 u/s instead of CD12 this time, and hopefully that extra day will help us to see slightly more mature follicles at the time of the u/s... And we can monitor at home with OPK to make sure I don't surge earlier, but otherwise perhaps we can wait til CD14 or 15 to trigger...
Those are our thoughts and tentative plan. I left a detailed message at the Dr's office and now I am waiting for another call back.
Thanks again for all of your thoughts and kind words - keep em comin if anyone else has 2 cents to add. I am starting to think that in addition to taking a village to raise a child, it may very well take us a village to conceive one!
Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012
5 medicated IUIs w/ RE (March - July 2013) = BFN
Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer! *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581 *********William George born June 4, 2014*********TTC with RE since March 2012
3 missed O's, 6 IUIs = 1 BFP then 8 w M/C, 5 BFNs
(2 unmedicated IUIs, 2 clomid IUI, 2 femara IUI)
Shared maternity/partner IVF, transfer #1 BFP!
EDD 11/28/13
No kidding
back in my hetero days I was scared to death of getting knocked up. Based on our sex education class you'd think even fooling around would result in a pregnancy! When DP and I talked about having kids together 7 years ago I imagined we'd just do it at home with a vial of sperm and badabing, badaboom, a baby. No one ever told me an egg only lives something like 12 hours, and that sperm may or may not find their way up your uterus, and that the uterus is a hostile environment already for sperm...
And I get why they did that (to keep us from making a mistake when we were far too young) but they also gave us the impression that we could get pregnant anytime, anywhere and have absolutely no trouble.
Update: I just had a long conversation on the phone with my RE
She told me that she does not support the back-to-back IUIs b/c there is no increased success rate from her research, and she also told me she doesn't think I need the trigger shot anymore and I can wait for my body to feel the eggs are mature enough to release in terms of timing b/c we know that I am ovulating on my own. She also does not think I need the CD12 u/s since she says that she has enough data now on how my body responds to 5mg of Femara, and now she just thinks it is a waiting age to see when I will get pregnant. Since she knows I am paying out of pocket for everything, she wants me to save the $350 that I will save by not having the trigger and not having the u/s and just "go back to basics" with less intervention and see what happens.
So, my wife and I discussed and that is what we are going to do. We trust he RE and have no reason to believe that this is not a reasonable approach. We will save the $350 and see what happens for IUI#5 with just the 5mg of femara and no monitoring and no trigger. If the 5th IUI doesn't work, we will go in and have a face-to-face consult with the RE about next steps.
Me - 30, My wife - 31 , Together for 10 yrs - Married August 2012
5 medicated IUIs w/ RE (March - July 2013) = BFN
Fresh IVF Cycle in September 2013 resulted in 18 mature eggs, 16 fertilized, 12 made it to day 5. Transfer of 2 Grade A blastocysts on 9/15/13, and 10 embryos in the freezer! *****BFP on 9/25/13 - betas: @10dp5dt = 232; @12dp5dt = 465; @15dp5dt = 1,581 *********William George born June 4, 2014*********I'm really sorry that this IUI wasn't successful. This process is so emotionally taxing and I really feel for you.
For what its worth, the approach your RE wants you to take for your next cycle is exactly what we did after our first two failed IUIs, in which I took 5mg Femara, midcycle U/S, and Ovidrel trigger. I did have a midcycle U/S with IUI #3 on CD15 and that is how I know that my follicles were much larger than with IUI #1 and #2. Two of the next three IUIs resulted in pregnancy.
Someone else mentioned acupuncture. During a couple of my cycles, I used acupuncture to help with both the fertility and the emotional aspect. I can't say for certain whether or not that contributed to my getting pregnant, but those two cycles resulted in pregnancies. Where I live, there is a community acupuncture place that charges on a sliding scale (you pay whatever you want). It was really affordable. Just a FYI in case you're interested.
Despite all the science behind reproductive technology, we're all individuals and we each have to find the right combination that works for us. Wishing you much luck and positive thoughts that you are headed in the right direction.
It sounds like you already have a plan, but for future reference (in case you need it, which I hope you don't), here's my 2 cents on breaks.
I never did decide, myself, whether they were a good idea or a bad idea. I did take breaks during our IUI process (generally a month/cycle at a time) but they weren't entirely voluntary. I took them because we had a trip planned that would have coincided with an IUI, or because we needed to take some time to pick a new donor, or because we were switching to the RE and needed to go through testing. I was always frustrated by them because it was a month during which I KNEW I wasn't going to get pregnant, and it already seemed like it was taking forever (still taking forever!).
That said, there were certainly benefits to taking them. I could theoretically relax a bit, though I'm not sure I ever really did (I'm better about that now). It took some pressure off, temporarily. It gave me time to make decisions (like picking a new donor or a choosing a new course of action) without being subject to the timing of my cycle. Right now I have to take two cycles off, and I am using it to try to relax a bit, lose some weight/get back into being healthy, and do things I can't necessarily do or are not comfortable doing while pregnant (like painting our front door and shutters).
I'm sorry this cycle didn't work. I hope your new plan with the RE saves you some money AND works for you!
9 IUIs = 9 BFNs
IVF October 2012: 22 eggs retrieved, 17 fertilized, 5 frozen
ET #1: 1 blast = BFP; Blighted ovum discovered at 7w5d; D&E
FET #1: 1 blast = BFP; Missed m/c discovered at 9w5d; D&E
Karyotyping: normal ~ RPL Testing: normal ~ Hysteroscopy: normal
FET #2: 1 blast transferred 10/25; BFP 10/31!
EDD 7/13/14 ~ Induced at 37w4d due to pre-eclampsia ~ Born on 6/28/14
*Everyone welcome*