We've done two Clomid cycles without IUI and two with IUI.  I know two IUI's isn't that many but I am so ready to move on to IVF. I just don't believe that IUI is going to work for us.  How many cycles have people done before moving on to IVF.  I am thinking one more... is 3 too few?                
                             
        
Re: How many IUI's before IVF?
Trying since Jan 2011. Unexplained IF.
2 IUIs = BFN.
1 IVF (Dec 2013) = BFN.
FET, 2 frosties (June 13, 2014)
14dp5dt-June 27 -BFP, beta 2061. 2nd beta >5000, 3rd beta >5000, 2 sacs 06/30.
Twin Girls - 02/11/15 - at 37 weeks (no NICU, home with me at 3 days).
June- Femara 7.5mg + Trigger + IUI = BFN August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
September- Femara 5mg = CX - No Response on Left = BFN October- 100mg Clomid + Trigger + TI = BFN
IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176 c/p @ 4w4d
FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
FET #2.2 Scheduled for September 20th
2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
2015- 2 failed FET. We are done
SURPRISE! BFP 8/8/16 EDD 4/1/17
************** Siggy Warning************
Married August 2012 -- Me (40 yrs old) My husband (45 yrs. old)
RE referral from ObGYN in late Jan. 2013 -- Testing Confirms Unexplained IF
IUI #"s1 - 3 (Femara + IUI) April - June 2013 - all BFN
Decided to do IVF... Began stimming on September 10th! Egg Retrieval 9/20/13. 19 eggs: 6 to mature to freeze after 6 fertilized with ICSI
3 morula stage embryos transferred on 9/25/13.....Beta #1 on 10/4/13/ = 7.5 Beta #2 on 10/6/13 = negative
IVF#2 - Lupron plan (set to begin on 10/28/13) (Planning on thawing and fertilizing our 6 eggs with ICSI as well as all of the mature eggs they retrieve with this fresh cycle.)
Late October 2013 - ectopic pregnancy - methotrexate injection....benched 3 months
CD1 - 12/5/13...Lupron set to start on 12/26/13; CD1 - 1/2/14....Baseline 1/3/14....begin follistim tonight and continue with lupron. (Got my calendar today! IVF#2 is a go!)
ER = 1/14/14 (11 eggs....9 were mature. 9 fertilized. Of the 6 mature eggs we thawed, only 4 fertilized. At this time, we have 13 eggs fertilized and growing. Waiting for news about a 3-day or 5-day transfer.)
ET = 1/19/14 (5dt).....3 blastocysts transferred! (All nine embryos didn't make it to freeze. =( )
Beta #1 = 1/28/14 (2 weeks after ER) BFP! 209 (9dp5dt) EDD 10/7/14
Beta #2 - 1/30/14 (11 dp5dt) 302
Beta #3 - 2/3/14 (15 dp5dt) 1222
Ultrasound set for 2/17/14......TWINS! Twin A - HR 124 bpm; Twin B - HR 126 bpm
Final Ultrasound with RE 3/10/14 - Twin A - HR 176 bpm; Twin B - HR 177 bpm.
PAIF/SAIF Welcome!
IF, 5 losses, 1 son, 1 on the way.
Like others have said, it depends on your diagnosis. We are MFI. He was going to do a couple natural IUIs, then a couple medicated IUIs before moving to IVF. However, that all depended on his post-wash counts.
When we are ready to go back to the RE in a couple months, I'm going to suggest skipping the natural IUIs and trying a lightly medicated IUI to hopefully increase our chances. We will probably do three before moving on.
TTC since March 2012
DX: MFI (4% motility)
Cycle 13: Natural cycle w/ HSG test = BFP
Identical twins!
Lost my angel boys at 10.5 weeks
Cycle 14-16: Natural Cycles = BFN
Cycle 17: Follistim + Trigger + IUI = BFN
Cycle 18: Natural Cycle = BFN
Cycle 19: Follistim + Trigger +IUI#2
Polyp found: SIS 11/11 - hysteroscopy 11/14
Cycle 20: Follistim + IUI#2 = BFFN
Cycle 21: Follistim (adj. dosage) + IUI#3 TI = BFN
IUI cancelled due to weather
Cycle 22: Follistim + IUI#3.1 = BFN
Cycle 23: treatment break, IVF consult
Cycle 24 - 26: natural cycle w/ acupuncture + Chinese herbs = BFN
Cycle 27: Follistim + IUI#4 = BFFN
Natural Cycles until IVF
Cycle 30: IVF#1 - Starting with Menopur + Follistim + Ganirelix
17 retrieved, 12 fertilized, 5dt w/ 2 blasts, 5 frosties
Betas: #1-156(9dp5dt), #2-1200(13dp5) #3-6112(17dp5)
Ultrasound #1 10/6: 1 bean!
TEAM BLUE!
My Chart
~~ALL WELCOME~~
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
I think this really depends on your diagnosis. Both REs I saw recommended moving on to IVF for us after 3 clomid + IUIs. We are "mostly" unexplained and are OOP. Both felt that the money spent on injects + IUI would be better put towards IVF, since the success rates are so much higher.
TTC #1 since August 2011
My Blog
September 2012: Start IF testing
DH (32): SA is ok, slightly low morph, normal SCSA Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA
October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos
November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues. Converted to freeze all due to lining issues. 2 blasts frozen on day 6!
January 2015: FET #2 Cancelled due to lining issues
April 2015: FET #2.1
PAIF/SAIF Welcome!
This. We only did two due to MFI, but my RE said he always likes to do an injects IUI before moving on to IVF as it also gives him a good idea of how you are going to respond to injects before going all in with IVF so that he can best anticipate the right protocol and starting doses for you. I don't think it is coincidental that he has the lowest IVF cycle cancellation rate in a 10+ RE practice!
Me: 31, PCOS DH: 37, low morph and low counts
IVF #1 Lupron/GonalF (Dec 2012)= 30R, 21M, 21F with ICSI, 18 HIP frosties!!!
FET in August 2013
I start my first round of clomid on Saturday too! My doc is combining clomid with injectables and IUI. Again its probably based on your specific problems as other ladies have said. My problem is that my eggs don't mature before ovulation so DH's little swimmers can't fertilize them. Im hoping that this treatment works out. I wish you all the best of luck and plenty of baby dust! Lets go July...ladies lookin' for a BFP!
Our RE recommended that we do 3 rounds of IUI before moving to IVF.....but he said that we can do as many as we want. We are on our 3rd now, but if it works, it sure is a lot less money then IVF.
We are using Femara and consistently have at least 2 follies each time. Our RE said that using injectables wouldn't help our odds enough considering it's an extra $800 per month. Since we have 2 follies every time, adding injectables would just mean that that we might have 1 or 2 more....but that is just a maybe. So if we can be on meds that cost $9 a month and still produce 2 follies each time, then no need for injectables.
Little Man arrived 3/28/14 at 10:32pm
9 lb 1 oz & 21 3/4 inches
SA - Normal CD3 Bloodwork - Normal HSG- All clear!
July 2012 50mg Clomid CD3-7 Trigger+TI = BFN
August 2012 50mg Clomid CD3-7 Trigger+IUI = BFN
September 2012 50mg Clomid CD3-7 Trigger+IUI = BFN
October 4th LAP - Mild Endo - All Removed
Treatment Break 3 cycles = BFN
1st Treatment Cycle Post Lap --
February 2013 50mg Clomid CD3-7 Trigger+IUI = BFN
March 2013 50mg Clomid CD3-7 Trigger+IUI = BFN
April 2013 Break Cycle ~~~ May 2013 Meet with RE discuss next steps
July 2013 IVF ~ Stims start 6/28
ER 7/10 20R/14M/14F
Day 3 - 10 Embryos
ET 7/15 Transferred 1 Blast on day 5 - Froze 6
7/24 Beta 1 150 7/26 Beta 2 313 7/30 Beta 3 1,084 Beta 4 3,000 Beta 5 8,120 1st U/S 8/8
With our mild MFI and my LPD my RE recommended doing four IUIs because he said 80% of people that are candidates for IUI (ie can be brought fully to ovulation and have enough sperm for IUI) get PG within the first four. And those 20% that don't get PG in that first four don't seem to have better chances by doing more.
That said, we did land in that percentage since we got PG on our fourth IUI but had a c/p m/c. So instead of moving on to IVF after our fourth he said he was fine with continuing a few more IUIs since we'd shown that everything happened as it was supposed to (sperm met egg, I was able to implant, etc) but that I just came down on the side of the odds for my age of 35, that 30% of pregnancies will end in m/c. We finished our fifth IUI a few weeks ago and agreed that while we could do another one or two, we'd rather move on to IVF due to success rate and money concerns.
IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
IUI#5 BFN (April 2013)
S/PAIFW , S/PALW
My Blog
1/7/2015 Twins born @ 34 weeks
All of this. We are not doing injects per the recommendation of my RE. We did 4 IUI's, and are moving on to IVF (hopefully) this cycle.
** After 2 1/2 years of Unexplained IF, 2 failed medicated cycles, and 4 failed IUI's - our baby girl came to us through the miracle of Mini IVF! **
We are OOP for EVERYTHING too! Did your doc say you could skip over the IUIs and go right to IVF? We will give it 2-3 tries
We were lucky on IUI # 4....twice but unlucky in that they didn't stick. Since we got a bfp on a IUI cycle, we knew we could connect and implant so we were willing to go more. We have done a total of 8 IUIs but hopefully we are moving on to IVF after my next AF.
Married 11/27/09 and TTC right away
Dx: Complete septate uterus with cervical duplication, endometrial polyps, PCOS, endometriosis, hypo thyroid, luteal phase defect
4 uterus surgeries to correct my complete septum and to remove polyps and 2 years of seeing the RE, medicated cycles and IUIs
Baby 1 and 2: BFP 3/3/11 with 2 babies EDD 11/1/11, M/C 4/6/11
Baby #3: 8/11 pregnant EDD 4/27/11 and m/c:(
Baby #4: 10/12/11 BFP! EDD 6/16/12m/c 10/26/11
Baby #5: 3/13/12 BFP! EDD 11/25/12 ANOTHER m/c
Baby #6: 2/14/13- BFP! EDD 10/24/13, CP 2/19/13
Baby #7: 3/15/13- BFP! EDD 11/27/13, another CP
Baby #8. BFP 5/19/13 EDD 1/22/14. 8 was not our lucky number
4th septum resection on 5/31/13.
Baby #9: 6/29/13 BFP. C section scheduled for March 5th!
My miracle baby was born March 5 at 9:33am. He was 8 lbs 12.5 oz and 21.25 inches long!