Postpartum Depression

anyone ween off of zoloft

I've been taking the generic form of zoloft since I was pregnant almost 3 years ago. I'm on 50mg and want to ween off of it.  I've tried taking one every other day but that did work because after a few days I was feeling not myself.  My doctor said it was ok for me to get off of it but didn't really give me much instruction.  Has anyone here weened off of it successfully and how did you do it?  I just bought a pill cutter and am thinking of just cutting it in half to 25mg and see how that goes
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Re: anyone ween off of zoloft

  • No answer for you but I am also on 50mg of Zoloft and am curious to see the responses.

    Do you mind me asking why you have decided to ween off? I have been on it for about 5 months and have never felt better. I don't know if I ever want to ween!
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  • imagemagpiemama:
    No answer for you but I am also on 50mg of Zoloft and am curious to see the responses. Do you mind me asking why you have decided to ween off? I have been on it for about 5 months and have never felt better. I don't know if I ever want to ween!

    a few years before I was pregnant I was on ativan once a day because of a very intense family situation.  After a year I was taking it as needed until I got pregnant. Had to get on zoloft instead and have stayed on it ever since.  I developed depression when I was pregnant and really needed it plus a lot of the pregnancy symptoms I had made me anxious.  It definitely helped that and only took about a week before I noticed a good improvement.

    Currently and for the last couple years I feel like there are no stressors in my life and I'm not depressed.  that went away after I had the baby.  I've just been putting it off because I'm scared of the weening side effects.  I figure if I can get thru the weening process I'm good.  Plus my doctor thinks I'm fine to get off of it but it seems like the doctors want you to stay on it.  It's not something I want to be on the rest of my life. 

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  • Never weaned off Zoloft, but other meds like it. You are suppose to cut it down like you said and take the 25mgs for 3 to 4 weeks, every day. Then you can cut the 25 in half and do the same for another 3 to 4 weeks. After that you may be fine to stop it all together. It can take anyone a few months to wean off a med...if you want minimal side effects. It is well worth the wait...trust me! Go slow!
    PPD/PPA Mom...it has been super hard, but I'm making it! Slow steps...
    Mom to Carter (6), and Calianne (1).  
    Proud VBAC, natural birth, breastfeeding, cloth diapering momma!


  • I was always told to keep cutting the pill in half. 

    So cut it in half and take 25 mg. Do that for a week (or two). Then cut it in half again (so ... roughly 12 mg) and do that for another week (or two). Then take the pill every other day.

    If at any point you feel weird or depressed/anxious, just go back to the previous step and take that for a little bit longer. 


    Evelyn (3.24.10), Graham (5.30.13) & Miles (8.28.16)
  • Thanks for the replies.  I'm going to start weening tomorrow
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  • LJR 84LJR 84 member

    I weened when TTC this baby. I was on 100mg. I went down to 50mg for about a month. (By cutting pills in half). After that, my doctor wrote a script for 25mg. I took those for about two weeks before taking one every other day and eventually just stopping.

    There was definitely a period of feeling "off" and more irritable than normal, but my doctor told me that was completely normal. Before long I felt as good as I did before I had the PPD! Now that I'm pregnant, I've had no problems. 

  • I tried it. It made me pretty sleepy, even though I took it at night. And my pills are only 25 mg. I tapered it very slowly; 3/4 pill for a week or two, then down to a half a pill, then 1/4 of a pill. I tried doing 1/4 every other day, but that's when I started to feel it and went back to 1/4 pill daily. I might try again in a few months.
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