Xp from secondary IF: RE results

mariantheb · June 2013

I had 3 rounds of failed clomid after trying to conceive #2. i conceived DS on the first try 2 years ago. DH and i are 33. after the clomid did not work, my obgyn referred me to an RE. So after my first RE appointment, I received not great news. My E2 tests came back at 57; they like under 50, my FSH was good, but my AMH is extremely low, like .08. This month, we are doing all diagnostic work like hsg (Thursday), sperm analysis, etc and then figuring out our best option. We are hoping to move on to follitism, trigger, and iui next month. I am just so sad and I feel like my body is failing me. Can anybody else shed some light on my results and/or have positive stories to share?

IBackBevo · June 2013

That E2 is not bad at all. Certainly not high enough to have artificially suppressed your FSH. I would not be concerned about that.

I am about your age (32), have undetectable AMH, too, and generally normal FSH. (I've had one high FSH reading, but I think it may have been influenced by other things since I've now had multiple normal FSH readings.) I was able to conceive my son through Clomid/IUI in 2012 when I was 31.

I have been really concerned about my AMH, but recently someone sent these two links me and I find them very interesting:

https://www.inviafertility.com/blog/conception/drvkarande/low-amh-level-is-not-predictive-of-decreased-chance-of-pregnancy-in-young-healthy-women#comment-4550

https://www.inviafertility.com/blog/conception/drvkarande/amh-level-and-menopause-part-i-does-amh-level-predict-age-at-menopause#comment-4551

The first basically says that low AMH in young, healthy women do not seem to be a predictor of reduced fecundability. This is consistent with high egg quality in these young women, despite a reduced ovarian reserve. However, they are not looking at women with ultra low AMH like us.

The second basically found that AMH was a predictor of when you would go into menopause, but basically only in older (greater than 40) women with low AMH and not in under 40 women as women with ultra low AMH levels between 35-39 were still found to be about 9-10 years out from menopause--which wouldn't even put them going through menopause particularly early.

I previously found a study that says once your AMH went undetectable it meant you were about 5 years out from your last period. However, the study only looked at women who were going through normal menopause and in their 40;s...not at "young" women with undetectable AMH.

Therefore, all of this makes me seriously doubt the predictability of low AMH in young women.

FYI, I'm not currently even going through ART, but the last RE I went to (about 2-3 months ago) recommended that DH and I just do IUI when we were ready.

Do you know your AFC? If your AFC is decent (and with proven fertility once before), I think if I would be inclined to try a couple rounds of Clomid or Femara+ IUI before jumping into IVF.

itsmevkb · June 2013

I too got pregnant quite easily the first time around and then we started having problems when trying for our second. In our case my husband's sperm was partially to blame (borderline count and motility and 0% morph) and then I was considered "older" at 35. My antral follicle count was on the lower than normal for my age but my FSH was still okay. Back then they didn't test AMH, but I had it tested a few years ago and it was very, very low so I'm sure it would have been low also at that time.

Honestly, I know having low AMH isn't good but I've been able to get pregnant six times, three with medical assistance and three without, so I never say anything is hopeless.

Saraevh · June 2013

Sorry you are going through this. A lot of us know how it feels to be slapped in the face with crappy test results when you are 'young.'

IBackBevo is pretty much the queen of AMH research so I think she gave you some great info, but I too got a low AMH diagnosis (at the ripe age of 27 after having my first child), went on to have another child and am currently pregnant with a third so don't give up or feel like it is hopeless. My RE told me that although my AMH was very low for someone my age, the fact that I was/am so young is more important because my egg quality should be good even though my egg quantity is low.

I know everyone is different, but I think starting out with IUI is a good place to begin especially if you don't have any MFI at all.

Good luck to you.

Want a personalized experience?

Xp from secondary IF: RE results

Re: Xp from secondary IF: RE results

Choose Another Board

Search Boards