Infertility

No words

Got the call from the RE. Extremely rare egg issue. WTF appoint today instead of my graduation ceremony.

Devastated.  

***WARNING***

TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

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Re: No words

  • Omg. I'm so sorry to hear that!

    Married my best friend on 9.6.11 
    Me 31 DH 29 
    TTC since 12/2011 
    Me - all normal test results 
    DH - SA #1, #2 and #3 - 0% morphology 
    Straight to IVF w/ ICSI 
    April 3 - start date for BC 
    April 18 - tentative start date for injections 
    Tentative IVF dates: ER - 4/27 and ET - 5/3!! DELAYED.
    IVF #1 - May 6 - Estrace
    May 17 - started injections!
    ER and ET end of May!! BFFN :(
    FET #1 - June 28th - BFP!!!! :)
    Beta #1 - 164, Beta #2 - 381
    1st u/s 7/16/13 - 2 sacs with yolks! 1 smaller than the other - Possible Twins?! 
    2nd u/s 7/26/13 - 1 healthy baby with heartbeat of 123bpm! Second sac empty. Next u/s 8/5/13.
    8/5/13 (7w2d) - no heartbeat. Lost our precious LO :-/
    D&C on 8/12/13 - finally neg hcg 2 months later on 10/3/13.
    Saline Songram on 10/10/13 - found polyp :-( post-poned again.
    Hysteroscopy on 10/29/13.
    FET #2 - BFP!!!! :-) 
    Beta #1 - 265, Beta #2 - 692
    12/24-12/28 (6w) - lost our LO (2nd miscarriage in a row)
    RPL panel and Karyotyping; results all normal!
    Started bcp's 1/24/14; saline sonogram 1/30/14 - All clear!!
    IVF #2 02/15/14; ER 02/26/14 - freeze all due to mild OHSS. 
    7 blasts; PGD on all 7 - all 7 normal!!!
    FET #3 4/8/14; BFP!! :-)
    Beta #1 - 235, Beta #2 - 539
    1st u/s - It's TWINS!!!!
    2nd u/s- both babies measuring on track! Heartbeats of 118 and 122!!
    EDD: Christmas Day!!!

    ** ALL ARE WELCOMED **

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  • F$@k. My heart is breaking for you right now. Internet hugs can't even begin to express my heartbreak for you. I'm so sorry.  

    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • oh no, i am so sorry to hear this... keep us posted on the appointment.  sending hugs your way.
    Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
    Started TTC 2009 with RE after 6 months.  
    Clomid + Trigger x2; 
    IUI + Femara x1,
    IUI + Follistim x2;
    IVF #1 (MDL) February 2013- BFN.
    IVF #2 (antagonist) May 2013, First BFP of my life. 
    Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


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  • Oh no! I'm so very sorry to hear this... :(

    Sending you {{{hugs}}} and keep us posted... 

    *** Trigger Warnings ***

    TTC #1 since March 2011
    Dx = Unexplained IF
    1 medicated TI cycle & 4 clomid IUIs = all BFNs
    June 2013 IVF #1 = 6 frosties + BFP!
    DS1 born 2/14

    TTC #2 since December 2014
    May 2015 unassisted BFP ended in m/c at 7wks
    April 2016 FET #1 = BFN
    June 2016 FET #2 = c/p
    August 2016 FET #3 = BFP!
    DS2 born 4/17
  • I'm sorry this happened to you. You and DH have been through so much. Why must our journeys be so hard? :-(

    Me & DH (33), 3 Furbabies, TTC since October 2011
    Day 3 #’s (Dec 2012) FSH 9, AMH .77, LH 2.4, E2 31, AFC 9 

    DX: Me-DOR + No Tubes, DH-Fine

    Ectopic 2007; lost tube/2nd tube removed Dec 2011 (hydro)

    April 2012=IVF#1- EPP Antag+ICSI, 2R,0F (BFN), Now dx’d with DOR.

    June-July 2012=IVF#2- MDL+ICSI&AH, 8R,4M,3F (BFP 9dp3dt) Beta#1 at 11dp3dt=36, Beta#2 at 15dp3dt=156, Beta#3 at 19dp3dt=671, dx'd with SCH, no growth-m/c at 7wks/Lap Dec 2012 to remove small fibroid.

    Feb 2013=IVF#3-MDL, 2/1=baseline, started 10 units mdl, AFC-7, 2/3 start gonal f, self cxld cycle b/c of low e2.

    April 2013=IVF#3.5-(with new RE)AG/ANT Conv + ICSI. 4/10-4/23 bcp's, 4/20-4/27 lupron, 4/28-ganirelix until end of stimming, 5/2-600 gonal f, 5/4-add 1/2 vial menopur, 5/13-ER (9R,1M,1F), 5/17-ET, 1 beautiful 8 cell (please be my sticky baby!!!!) 5/28-BFFN.

    Oct 2013=IVF#4-LLP+ICSI &AH, 10/14 (6R, 2M, 2F), 10/17-ET, 1 seven cell & a six cell, BFP at 9dp3dt, 1st beta=56, 2nd beta=52, CP.

    Jan 2014=IVF #5-LLP, Cxld after 6 days of stims due to fast response and lead follicle. 

    March 2014=IVF 5.5-LLP, Lupron 3/10, BL 3/18, 11 days of stims, Trigger 3/29, ER 3/31. 7R, 2M, 2F. ET 4/3. Txfd one 5 cell & one 9 cell. BFP on hpt from 7dp3dt & on. Praise be to God. Beta #1 at 11dp3dt=106, #2 at 13dp3dt=239. First u/s 4/28, measuring on track & heartbeat seen. 5/5-2nd u/s, measuring on track with strong heartbeat. 5/12- 3rd u/s & released from RE. Grow baby grow, we love you! Baby G&T is a BOY! Born 12/2014 via c/s! 8lbs, 8oz & 21 inches.


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  • Oh NO!!! I'm hopeful that they will have answers that help today. If not, feel free to throw fits and cry. I sure would.
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
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    PAIF/SAIF/Everyone Welcome! 


  • I'm so sorry.  IF is unfair.  Let us know please.
    Me:40 DH: 43 m/c #1 4/8/08 @ 5w::natural
    m/c #2 missed m/c discovered 12/11/08 @ 8w3d :: d&c 12/15/08
    Feb 2009-began seeing an RE:: DX with unexplained IF
    Sept 2009 -2010 TTC using femara ...eventually work called me out of town.
    June 2011 DX with thyroid cancer-forced to put baby making on hold
    11/15/12 IUI #1 BFN and 12/15/12 IUI #2 BFN
    Feb 2013 IVF-BFN:: April 2013 FET-Cancelled:: July 2013 FET-1 frostie
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  • MJ14323MJ14323 member
    I'm so sorry.  {{HUGS}}

    **SIGGY WARNING**

    TTC since Nov 2010 | Me: 29, DH: 31 
    DX - Severe DOR, Stage II Endo
    6 rounds medicated TI, 3 failed IUIs, 2 failed IVFs
    After nearly 4 years of trying, our 1st BFP on IVF #3 (5R, 3M, 3F, 3 day 5 blasts frozen) 
    FET - Beta #1 - 116, Beta #2 - 266!! 1st U/S on 10/6 - HB 121 and measuring perfectly! EDD 5/30/15

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  • htn1763htn1763 member
    oh no. i'm so sorry. I really hope you get more answers soon.

    Me: 33 DH: 32 SA#1 low count (6mil) SA#2- now in IUI range!(30mil) Dx:MFI
    11/1- IUI#1,12/1- IUI#2, 1/2- IUI#3 all BFFN
    IVF#1. Long Lupron.ER 3/8 10R,4M,5F. ET 3/3-one 1AB, 2 frosties 5dp5dt-BFP!! Beta 3/25-794 Beta 3/27- 1794
    First u/s 4/8 saw hb. 4/22 missed mc 8w3d. d&c 4/26
    FET #1- bcp start 6/9. ET 7/12. 2 perfect blasts.5dpt-BFP!! 
    Beta 7/24 -1,239!! Beta 7/26- 2569 Beta 7/29- 7120.  U/S 8/7 hb 118! U/S 8/14 hb 143! U/S 8/20 hb 170. Graduated!! Stick baby stick! 


  • So sorry to hear this, hope you get more information soon, thinking of you today.
    CafeMom Tickers
     Anniversary
    TTC since July 2011
    BFP #1: 2/15/12-Ectopic/Mtx at 6 wks

    BFP #2: 10/12/12-m/c at 5 wks. 
    BFP #3: 8/27/13
    Me: MTHFR, Low AMH (1.1), High NK cells and Antiphospholipid Antibodies.
    DH:MFI-Low morph (1%), DNA fragmentation: Excellent!
    5 rounds of clomid, 3 IUIs, and multiple non-medicated cycles- BFFN                                                      
    IVF with ICSI in August 2013 brought us our babies.  ER-9R, 7M, 4F w/ICSI  ET of 2-Grade 2 blasts. 
    + HPT at 6dp5dt. #1 (8dp5dt)- 105    #2 (13dp5dt)- 510  #3 (15dp5dt)- 960  #4 (17dp5dt)- 1889
    Dx shortened cervix, PTL, and preeclampsia during pregnancy.  Lots of medications and 13 weeks of bedrest, babies were born healthy at 34w4d!


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  • Wow. I am so sorry to hear this.
  • I am so sorry. TP going out to you guys!!
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  • So very sorry to read this.  ((((HUGS))))

    Me: 36, TTC since 2010 Met with an RE Dec 2012 Diagnosis: DOR (with high FSH) Jan-Feb 2013; IUI + Clomid, BFN March 2013; Cycle break since Clomid thinned my lining April 2013; waiting for AF to start injectables (plan = IUI) Plan for Summer 2013; Considering DE
  • Sunny BSunny B member

    I'm so so sorry :(

    You're in my thoughts.

    TTC since May 2012
    Me: 32 H: 31
    DX: MFI-Very Low Count, I have Hashimotos.
    IVF prep September 2013 cancelled due to Ovarian Cyst
    IVF #1 October 2013 Antagonistic Protocol with ICSI  ER 10/31/13 (18R 16M 11F- 6 blasts to freeze)
    ET delayed due to OHSS 
    FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!)
    FET #1 8/5/14 sET BFN 

    All welcome!
  • I am so so sorry.  IF is not fair!  I hope you get some good answers today. ((hugs))
    ****************SIGGY WARNING****************

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    TTC since 2011
    DH: 29, Severe MFI; grade III varicocele; surgery postponed till KU
    Me: 30, POF/DOR, factor II hetero, MTHFR homo
    5 IVF's, LLP, EEP, MDLF all BFN
    IVF 6 using DEB USA frozen eggs
    developed bilateral PE's from BCP, cancelled/delayed 6 mths, taking lovenox
    Feb'15 SURPRISE 1st BFP ever! EDD: 10/10/15, FX
    Still have frozen donor eggs on ice
    All are welcome!
  • I'm terribly sorry. I can't even begin to understand this level of devastation... Please let us know how you're doing, we all care about you.
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  • Thanks for the hugs. I'm still numb, but stubborn. 

    Apparently my eggs aren't metabolizing well. There is a mitochondria problem which is causing my smooth endoplasmic reticulum to aggregate. (yeah- kinda glad I teach middle science so I know what he is talking about it. still don't understand it)  He says the clinic sees about 1 case per year and they do over 3,000 ICSIs a year, so the last place probably saw it, but didn't know what it was.  Literature is scarce on the condition, and mine is the most severe my RE has seen. He has successfully treated 2 prior patients but the protocol is very different. I'd have to go into a menopausal state and make no estrogen but be on all the other hormones. And he would only push for 3-4 follicles with 2-3 eggs. And we are using testicular sperm (the best testicular sperm they've ever seen, but still...) 

    We don't know whether to try his protocol or look at donor eggs. We were able to have them agree to let us pay cash for this cycle at the accepted insurance rate so we would still have one covered cycle. We need to make that decision by tomorrow. So no time to cry- got to put my thinking cap on and come up with a plan. Unfortunately DH and I had such a hard time with donor sperm because neither one of us have brown eyes and we're both O blood type, so each place gave us like 5 possible donors. It's going to be even slimmer with donor eggs.  No idea what to do. 

    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

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  • I am so so sorry. What kind of odds does he give you with the new protocol? Why do you have to decide in one day? Seems like they ought to let you think about it! Good luck with whatever you choose!
    ---------------Siggy Warning--------------------


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    Me: 32, DH: 34  / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
    4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
    9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
    5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
    12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
    FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
    BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
    First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d

    5/27/2014: Team purple!!!!  EDD 10/10/2014 / 
    Delivered by c-section at 32w0d 8/15/2014 due to preeclampsia/HELLP syndrome
    Baby Boy 4lbs 1oz, 17 inches
    Baby Girl 3lbs 5oz, 16 inches


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  • imageAurora1181:
    I am so so sorry. What kind of odds does he give you with the new protocol? Why do you have to decide in one day? Seems like they ought to let you think about it! Good luck with whatever you choose!

    I am not sure. Of the 3 cases he's seen, they all worked but were previously great responders to drugs, unlike me, and didn't have MFI, unlike me. Not sure I can compare.

    Tomorrow they are billing the insurance for the procedure. Once the insurance gets billed, we are no longer covered for IVF, but if we pay cash for the ER then we get one more try including all meds covered... and this could include a fresh donor too maybe. Trying to get it all squared away ASAP. But if we decide to go donor embryos, then we don't need to pay for the last ER because ET will be covered. I hate that money is such an issue, but that's just how it is. Looking into loans to cover donor fees and such- so much not covered also.

    Wish I had more time, but I have been at this pc all day except for WTF appt so it's been keeping me occupied and trying to look at possible ways to have a baby. Has to be better than crying with a highly caffeinated, alcoholic drink, right? 

    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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