I had an insane amount of blood work done back in April and I finally had the opportunity to talk to my RE about the results on Friday afternoon.
One result showed that I have a Vitamin D deficiency. My RE surprised me by saying that studies show strong evidence that Vitamin D deficiency can cause implantation issues for those using DE/DEmbryos. It seemed odd that she only mentioned this in the case of donor egg/embryo but I didn't think to prod further. She is prescribing Rx Vitamin D for 6-8 weeks then I'll be on a regular maintenance OTC dose after that.
She is the TPR director at my clinic and her specialty is donor issues so I trust her, but I thought this was interesting and had to share. If you haven't had your Vitamin D levels checked, it may be worth looking into with your RE. Every little bit helps, right?
Re: Vitamin D and DE/DEmbryo implantation
***signature & ticker warning***
Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!
Him: 29 ~ perfect swimmers
Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
Stopped BCP 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
BCP to manage endo from 10/2012 to 12/2012.
FET w/donor embryos #1: 10/2013 Cancelled
FET w/donor embryos #1.2: 11/2013 ~ ET of 2 beautiful blasts on 11/27.
Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt) Beta 4: 8503(19dpt)
Twins with an EDD of 8/15/14! Team Purple
G&B born 6/30/14 at 33w3d via emergency c/s.
If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!
First mini-IVF Sept 2011... Only 1 egg! ... BFN
Switching RE
IVF#2 May 2012 9 eggs and only 2 sperm, WTH!
BFN
Switching RE's within practice
*~God gives his hardest battles to his toughest solders. Unknown.
DOR and AMA
2/12-5/12: 4 IUI cycles = all BFN;
7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
Lupus anticoagulant initially high, then found to be normal on hematology consult;
Follow up testing in September all clear;
Started synthroid for "high normal" TSH;
FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
12/12- Officially an OB patient!
Level 2 ultrasound at 20 weeks shows vasa previa and VCI
Referral to MFM and mandatory c section for delivery
Beautiful baby girl born at 34 weeks
Finally home after 15 day NICU stay!
Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
FET #3, early July 2014; beta 7/14, BFN
DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
FET #4- December 2014, yet another BFN
Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)
Added baby aspirin, prednisone, supplements, Metanx, and intralipids
Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN
Likely OAD- NBC
But seriously, when I was pregnant my endocrinologist checked my thyroid T3 and T4, and Vitamin D every 3 weeks. It is expensive 83.37 negotiated insurance rate but I was ok with that. Before pregnancy, he had me take a 50,000 IU vitamin D once a week, while pregnant I took 5000 daily and do that now as we gear up for our FET. Thx Liz!!
Me (43) and J (45) - same sex couple. And we don't feel 40+!
June'12 - First RE Visit
Sept. '12 - Tubes removed
Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
Loss due to umbilical cord clot...baby was perfect.
Jul '13 - FET#1 - c/p
Sept. '13 - FET#2 - BFN
Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
Dec' 26, 2013 - hb!!
EDD 8/20/14 with a baby girl!
Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
We live in Seattle and used SRM for our donor egg IVF cycle
My PCP actually checked my level and it was actually fine... Was surprised I was actually in the normal category of something for once in my life.
Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI (TTC#1 since 2009)
IVFs#1-4: (4/10-2/12) all BFN
Surprise Bfp (9/11) - c/p
DS IUI#1-2 (9/12, 10/12) - BFN
DS IVF: (11/12) - BFN
DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN
FET of 2 day 6 blasts: (12/13) - c/p
DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.
FET 5/14: 1 day 5 hatching blast transferred...another BFFN
Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus
New RE, additional testing reveals elevated NK Cells
FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October
April 2013 DE IVF= BFN
September 2013 DE IVF (Fingers Crossed) = BFFFN! again...
October 2013 FET of our last 2 = Beta Hellzz for 6-7 Weeks. M/C