Trouble TTC

WTF Appt Update (Long)

So I met with my RE last week due to the 3 medicated cycles not giving me a response.  I'm really glad I met with him because I think he put more thought into my situation and looked over all three last medicated cycles together.  He seemed surprised that I haven't cycled on my own at all.  Anywho, it was almost like he was thinking aloud to figure out what might work for me.

He wants to do one more cycle of min stim, but is switching me from Clomid to Femara to see if that might make a difference.  Additionally, instead of 2 days of injects, I will be doing 4 days (CD 7-10) and to ensure there isn't an absorption issue, he wants me to do them IM. 

He did say that our best option might be IVF.  He said he was hesitant to do straight injects with me because of the amount of undeveloped follicles I have on my ovaries (I have 25-30 on each) and it is such a fine line between just enough and too much and he doesn't want me to have a litter. 

Over the weekend, as DH and I have been talking, we are still unsure if we want to do IVF or move onto adoption - it'll just take us some time to sort it out.  One question that came to mind is what if we try for that "just right" amount and if I developed too many mature follies switch to IVF?  I don't know if this would be possible, but was wondering if anyone out there may have done something like this.

I'd really love any thoughts on any of the above.  Also, who out there has done self-administered IM injects?  I won't lie, I'm a bit nervous about doing them (even though I have a bit of a wait)!

TTC #1 Since 7/2011

Me: 30, PCOS with anovulation
DH: 38, Low Morph & DE
Rx: Metformin 500mg

Cycle #1: Clomid 100mg + Ovidrel = No Response, Canceled
Cycle #2: Clomid 150mg + Ovidrel = No Response, Canceled
Cycle #3: Clomid 150mg + Follistim + Ovidrel = No response, Canceled

Cycle #4: Femara 7.5mg + Gonal-f + Ovidrel + IUI = BFP!!!!

 

~ EDD 03.26.14 ~

Re: WTF Appt Update (Long)

  • I am on my first cycle of injects (but not IM - I feel for you there!)

    RE said at the beginning if I was overstimmed and had 6-8+ follicles that we would have the opportunity to convert to IVF if we decided that is what we wanted to do.  I know I read someone on thebump who this happened to as well (thought I don't remember who).   So yes it is possible.

    Good luck!

                        imageimage

                    image  imageimage
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    TTC #1 since November 2011
    Dx: Unexplained Infertility, probable endometriosis
    Feb-April 2013: Femara + TI: BFN
    May - September 2013:  Follistim + Ovidrel + IUI#1-4 = BFN
    IVF # 1 November 2013: transferred 1 perfect blast = BFN
    IVF # 2 April 2014: Endo scrape, transferred 2 blasts = BFP!! (first ever!), CP
    FET #1 June 2014: transferred 2 blasts = BFFN
    New Dx: Repeat Implantation Failure
     IVF # 3 November 2014 = BFP!!  Beta #1 9dp5t 272  Beta # 2 11dp5dt 626
    It's Twins! 
    *everyone welcome*
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  • I don't have any real advice.  Hoping you and your husband find an option you are both comfortable with.  Sending lots of positive thoughts you way....and of course lots of ((HUGS))

    **************SIGGY WARNING**************

    BLOG

    Me 32 :: DH 41

     TTC since November, 2011

    DH's SA : Excellent

    Lap and Hysteroscopy June 2012

    DX: PCOS, Stage III Endo, slight Adenomyosis, blocked tube, and probable LPD

    Treatments:  6 Months Lupron Depot injections; 1500 mg metformin; 3 cycles of Clomid + TI = BFN

    3 endometrial biopsies all were "out of phase" 

    September - December, 2013:  Break to lose weight and get healthy

    40 lb weight loss but still not ovulating "in phase"  

    February - March 2014: bcps + follistim + trigger + TI = BFP

     Beta #1 (12dpo): 30; Beta #2 (18dpo): 500; Beta #3 (25dpo): 7,000!!! 

    1st u/s 4/16: One beautiful hb at 144 bmp 

    2nd u/s 4/29: hb at 166 bmp.  Graduated from RE!!

    TEAM PINK! 

    Baby girl arrived on Thanksgiving day weighing 7lbs 6oz and measuring 20 inches

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  • RunCC37RunCC37 member
    I have no advice, but wanted to extend my best wishes to you. I hope you come to a decision that you are comfortable and confident with!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • No advice, but sending good thoughts your way!  So sorry for the news - I hope you and your DH come to a decision you feel comfortable with.  ((hugs))
  • jfb29jfb29 member
    Thanks ladies!  I know I can do the IM shot - needles don't scare me that much, I just know it won't be like the subQ which is so easy!

    TTC #1 Since 7/2011

    Me: 30, PCOS with anovulation
    DH: 38, Low Morph & DE
    Rx: Metformin 500mg

    Cycle #1: Clomid 100mg + Ovidrel = No Response, Canceled
    Cycle #2: Clomid 150mg + Ovidrel = No Response, Canceled
    Cycle #3: Clomid 150mg + Follistim + Ovidrel = No response, Canceled

    Cycle #4: Femara 7.5mg + Gonal-f + Ovidrel + IUI = BFP!!!!

     

    ~ EDD 03.26.14 ~

  • I was on clomid 1 time. The cysts I developed made my ovaries the size of cantaloupes and cut off my bladder needless to say after the surgery I never tried clomid again. I also tried femara a few times with no response what so ever. Like you I have about 30 follicles on each ovary so going to follistim (self-administered) IM injection was nerve racking.

    My RE was worried about the same stuff as yours. I am currently in the 2WW of my first round and it went fantastic! RE started me out on a really low dosage like 25mg and I was in for an ultrasound two days later. They decided they could up me to 50mg and I was back for an ultrasound two days later. Long story short I was in every two days and I only had 1 follicle develop enough for an egg which is what the RE wanted. Did the trigger shot and now?I wait!

    I would say before jumping right into IVF you should find out about getting put on an extremely low dosage (maybe a second opinion). I was worried about having to do the shots myself but it was super easy. Took me maybe 10 minutes the first time but after that I was a pro! I will say make sure you don?t get too close to your belly button though, I gave myself a nasty bruise.

     Sorry this ended up being so long...It just the first time I have been able to give advice on this board. :) Good luck!

     imageimage

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