Trouble TTC

Aw, why the hostility?

Well, after our post coital test this morning, looks like I have hostile CM and it is killing everything before it can get to my cervix Sad Doc said that it was too late in the cycle to do our first IUI, and that we're encouraged to BD tonight and keep our fingers crossed (she said that it's been known to happen on occasion for a woman to get pregnant, even with this issue). I have a second HCG Beta scheduled for the 23rd, so tomorrow starts the tww again...If it doesn't happen for us this cycle, we will be moving onto our very first IUI, which she sounded confident would work for us if we don't happen to get preggo this time around. Thank you all for listening and I hope you're having a good week so far Smile

Re: Aw, why the hostility?

  • Oh I'm sorry! Did they say there's anything you could do to help your chances anytime you are just trying on your own? Obviously IUI should bypass the problem, but I didn't know if there was any treatment options.

    Again I'm sorry for the not so great news today.

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  • jfb29jfb29 member
    Glad you have some answers!  Hopefully you won't need the IUI, but glad you have that as an option to help with the CM issue.

    TTC #1 Since 7/2011

    Me: 30, PCOS with anovulation
    DH: 38, Low Morph & DE
    Rx: Metformin 500mg

    Cycle #1: Clomid 100mg + Ovidrel = No Response, Canceled
    Cycle #2: Clomid 150mg + Ovidrel = No Response, Canceled
    Cycle #3: Clomid 150mg + Follistim + Ovidrel = No response, Canceled

    Cycle #4: Femara 7.5mg + Gonal-f + Ovidrel + IUI = BFP!!!!

     

    ~ EDD 03.26.14 ~

  • Thank you for your kind words, Cara. They didn't say anything that could help my chances right now (because there weren't any living sperm at all in my CM), but, I've read some things about improving your diet, drinking lots of water (which I'm going to do for the heck of it anyway), and taking Evening Primrose Oil supplements. I'm doing surprisingly well after the news. At this point, the more enlightened I become about what's going on with me, the more I know about the options we have and what our chances are.
  • Glad you are getting some answers even though it is never fun to hear you have hostile cm. Good to hear you have a plan. Fx for you!

    **************SIGGY WARNING**************

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    Me 32 :: DH 41

     TTC since November, 2011

    DH's SA : Excellent

    Lap and Hysteroscopy June 2012

    DX: PCOS, Stage III Endo, slight Adenomyosis, blocked tube, and probable LPD

    Treatments:  6 Months Lupron Depot injections; 1500 mg metformin; 3 cycles of Clomid + TI = BFN

    3 endometrial biopsies all were "out of phase" 

    September - December, 2013:  Break to lose weight and get healthy

    40 lb weight loss but still not ovulating "in phase"  

    February - March 2014: bcps + follistim + trigger + TI = BFP

     Beta #1 (12dpo): 30; Beta #2 (18dpo): 500; Beta #3 (25dpo): 7,000!!! 

    1st u/s 4/16: One beautiful hb at 144 bmp 

    2nd u/s 4/29: hb at 166 bmp.  Graduated from RE!!

    TEAM PINK! 

    Baby girl arrived on Thanksgiving day weighing 7lbs 6oz and measuring 20 inches

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  • imagejfb29:
    Glad you have some answers!  Hopefully you won't need the IUI, but glad you have that as an option to help with the CM issue.

     Yes, I'm hoping that we will be able to beat the odds of having a hostile cervical environment and get pregnant on our own this cycle, without having the IUI. But, if not, the IUI sounds very promising.

  • Sorry you didn't get the best news, but you have a great attitude about it!  FX that you will beat the odds!
    CafeMom Tickers
     Anniversary
    TTC since July 2011
    BFP #1: 2/15/12-Ectopic/Mtx at 6 wks

    BFP #2: 10/12/12-m/c at 5 wks. 
    BFP #3: 8/27/13
    Me: MTHFR, Low AMH (1.1), High NK cells and Antiphospholipid Antibodies.
    DH:MFI-Low morph (1%), DNA fragmentation: Excellent!
    5 rounds of clomid, 3 IUIs, and multiple non-medicated cycles- BFFN                                                      
    IVF with ICSI in August 2013 brought us our babies.  ER-9R, 7M, 4F w/ICSI  ET of 2-Grade 2 blasts. 
    + HPT at 6dp5dt. #1 (8dp5dt)- 105    #2 (13dp5dt)- 510  #3 (15dp5dt)- 960  #4 (17dp5dt)- 1889
    Dx shortened cervix, PTL, and preeclampsia during pregnancy.  Lots of medications and 13 weeks of bedrest, babies were born healthy at 34w4d!


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  • imagemonimu13:
    Sorry you didn't get the best news, but you have a great attitude about it!  FX that you will beat the odds!

     Thank you Smile I'm really trying to make an effort to be more optimistic about things, because I've been pretty depressed the past couple of months with the let downs, and that doesn't do me, or my husband any good. He's such an optimistic person, so having him cheer me on has been so awesome. Big Smile

  • rox825rox825 member
    Did they tell you what about it was hostile, like ph, consistency, etc?

    Baby Birthday Ticker Ticker

    TTC since Sept 2011, Unexplained IF
    Oct 12 - Jan 14: 3 clomid/TI cycles, 2 hysteroscopies, 2 IUIs, 1 BFP (MMC @ 12w), 2 more IUIs
    Feb 14: Gonal-f + IUI #5 = BFP! (EDD 11/4/14)
    Baby boy arrived 11/13/14!

  • imagerox825:
    Did they tell you what about it was hostile, like ph, consistency, etc?

    I believe it was consistency (too much). She said that the gland that creates the mucus, is treating the sperm as if it were an "unwelcome visitor", and makes too much to fight it off.

  • RunCC37RunCC37 member
    Sorry to hear, but glad that you're keeping a positive attitude!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • Sorry to hear that.  A girl I know had the same thing and got preg with just Clomid no IUI so it can happen.  
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • rrdiva1rrdiva1 member
    sorry about the news, but now at least you have answers and a game plan. Nothing worse than spinning wheels.Best of luck and huge hugs, stay encouraged!
    Married BF 6/29/2002/
    TTC Since Aug 2011/
    ME:34 all clear/DH:41 DX Severe MFI/
    IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2)

    IVF 2.0-Baseline 11/7/12 beta 0/All Clear
    Stim start 11/7/12//ER 11/19 11M//10F
    ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29
    stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan

    Ivf 3-frozen 3 poor 3day/fet=bfn

    Ivf#4 New dr. New protocol=beta1 197 beta#2 677 beta#3 1557
     u/s 8/13 =TWINS 2 strong hb
    Due Date 4/4/14

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  • rox825rox825 member
    imagebrandykid:

    imagerox825:
    Did they tell you what about it was hostile, like ph, consistency, etc?

    I believe it was consistency (too much). She said that the gland that creates the mucus, is treating the sperm as if it were an "unwelcome visitor", and makes too much to fight it off.



    Sorry to hear that, but in that case it sounds like IUI is a good option! Hope it will work for you.

    Baby Birthday Ticker Ticker

    TTC since Sept 2011, Unexplained IF
    Oct 12 - Jan 14: 3 clomid/TI cycles, 2 hysteroscopies, 2 IUIs, 1 BFP (MMC @ 12w), 2 more IUIs
    Feb 14: Gonal-f + IUI #5 = BFP! (EDD 11/4/14)
    Baby boy arrived 11/13/14!

  • AkieshaAkiesha member
    Sorry to hear that, any luck and you won't need the IUI. FX for you!
    My Ovulation Chart
    TTC since 0ct. 2011
    Me-34,DH-34
    Dx:Hypothyroidism 2008
    HSG- All clear CD 3 bloodwork normal
    SA- Abnormal Dx:MFI
    DH on 50mg Clomid 3x week
    BFP#1- 1/21/13 CP 1/24/13
    Cycle 18,19 & 20 50mg Clomid+trigger+IUI= All BFFN
    Cycle 21-25 Taking a break for now, still HIO Hoping!
    Moving onto IVF Next AF
    (PAIF/SAIF Welcome)
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  • ((BIG HUGS!)) to all of you! Thank you! Smile My fingers are always crossed for all of you, and you're always in my prayers!
  • RachnanRachnan member
    We were diagnosed with the same in January. Pretty shocking! Have moved onto IUI as well.  Hang in there!

    **Warning - Child Mentioned**

    Me: 33, DH: 39   Unexplained Infertility

    4 IUIs (chlomid) in 2013 which resulted in DS born in April 2014

    TTC #2 since August 2015

    5 rounds of IUIs (1 chlomid: resistent, 1 femara, 3 gonal f) = all BFN

    ER March 9: 26 eggs retrieved, 19 mature and 17 fertilized, 8 made it to genetic testing, 4 normal!

    FET #1 5/31 = BFN

    FET#2 7/26 = BFP!

    BabyFruit Ticker

  • imageRachnan:
    We were diagnosed with the same in January. Pretty shocking! Have moved onto IUI as well.  Hang in there!

    It was definitely interesting news. Thank you, and good luck to you with your IUI! Smile

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