Prometrium standard after 1st IUI?

Tshoff · May 2013

Hi, just had my iui on Saturday and was given a prescription for prometrium if I wanted to take it. Dont know if I need it or not? Does anyone know if its necessary? I was on Femara for five days, cd 37, and had a trigger shot day before Iui. Thanks!

riebeetee · May 2013

My RE puts me on it... it helps increase your LP in case that's the reason a pregnancy isn't sticking. If my cycle is successful, I'll stay on it until Week 12 when the placenta takes over. So far, I've only taken it through my 2ww. My RE phrased it that we want the perfect environment for conception, and to take away anything that could be preventing it (short LP).

Just make sure that you stop taking it if you aren't pregnant - you won't get your period while you are on it.

katib77 · May 2013

There are many REs that give it as a procausion. If you have no known LPD, some skip it but all it does it add progesterone so you are able to sustain implantation if you got PG and there was no other reason for a mc.
Because I have LPD and really low P4 readings a 7dpo I'm on it. But even on the supp last treatment cycle my P4 was still real low and they had to add supps. Personally, I say take it so you don't have any what ifs? In your mind.

Tshoff · May 2013

Thanks! Didn't know if once I started taking it, I had to continue the whole first trimester. Still waiting on blood work results so no idea if my progesterone is low or not. Pretty much unexplained infertility at this point. It's been three days post iui.

socialwkrsweetie · May 2013

katib77:
There are many REs that give it as a procausion. If you have no known LPD, some skip it but all it does it add progesterone so you are able to sustain implantation if you got PG and there was no other reason for a mc. Because I have LPD and really low P4 readings a 7dpo I'm on it. But even on the supp last treatment cycle my P4 was still real low and they had to add supps. Personally, I say take it so you don't have any what ifs? In your mind.

Kati, can I ask what your P4 levels are at 7dpo? I'm just trying to get an idea of what's considered low. Thanks!

babydreams13 · May 2013

My RE has me take Endometrin- Progesterone- in the 2ww after IUI. Its precautionary.

katib77 · May 2013

socialwkrsweetie:
katib77:
There are many REs that give it as a procausion. If you have no known LPD, some skip it but all it does it add progesterone so you are able to sustain implantation if you got PG and there was no other reason for a mc. Because I have LPD and really low P4 readings a 7dpo I'm on it. But even on the supp last treatment cycle my P4 was still real low and they had to add supps. Personally, I say take it so you don't have any what ifs? In your mind.

Kati, can I ask what your P4 levels are at 7dpo? I'm just trying to get an idea of what's considered low. Thanks!

Sorry - just saw this. If you were on a natural cycle your P4 should be 10 or higher. If it's a medicated cycle, they like it to be 15 or higher...but are still not worried if it's above 10.

On my natural cycles, I got 7's and 8's to determine I have luteal phase defect - but that was three years ago. On my first treatment cycle I had a strong ovulation of 25 for my p4. Since then it's never been above a 13. And on my last treatment cycle which was our m/c c/p my p4 at 7dpo was just a 4.3, so aside from the 200mg oral prometrium supps I was also put on endometrim vag tabs. At my first beta my p4 had gone up to over 10, by the second beta as I was miscarrying it went down. It was determined that it was a malformation with the egg, and with my age of 35, I fell into the 30% of my age group that just naturally miscarries. HOWEVER, if I was not on progesterone I would not have gotten pregnant at all as my P4 was too low to sustain implantation. While some might say "wouldn't you have rather not gone through the heart ache of m/c?" I personally am thankful to have finally seen those two pink lines, however short lived just to know that it *is* possible. Now we just have to hit that other 70% where the embie sticks around and grows. But to me progesterone supps are a blessing for people like me in order to even get pregnant. Gotta love science!

socialwkrsweetie · May 2013

katib77:
socialwkrsweetie:

katib77:
There are many REs that give it as a procausion. If you have no known LPD, some skip it but all it does it add progesterone so you are able to sustain implantation if you got PG and there was no other reason for a mc. Because I have LPD and really low P4 readings a 7dpo I'm on it. But even on the supp last treatment cycle my P4 was still real low and they had to add supps. Personally, I say take it so you don't have any what ifs? In your mind.

Kati, can I ask what your P4 levels are at 7dpo? I'm just trying to get an idea of what's considered low. Thanks!

Sorry - just saw this. If you were on a natural cycle your P4 should be 10 or higher. If it's a medicated cycle, they like it to be 15 or higher...but are still not worried if it's above 10.

On my natural cycles, I got 7's and 8's to determine I have luteal phase defect - but that was three years ago. On my first treatment cycle I had a strong ovulation of 25 for my p4. Since then it's never been above a 13. And on my last treatment cycle which was our m/c c/p my p4 at 7dpo was just a 4.3, so aside from the 200mg oral prometrium supps I was also put on endometrim vag tabs. At my first beta my p4 had gone up to over 10, by the second beta as I was miscarrying it went down. It was determined that it was a malformation with the egg, and with my age of 35, I fell into the 30% of my age group that just naturally miscarries. HOWEVER, if I was not on progesterone I would not have gotten pregnant at all as my P4 was too low to sustain implantation. While some might say "wouldn't you have rather not gone through the heart ache of m/c?" I personally am thankful to have finally seen those two pink lines, however short lived just to know that it *is* possible. Now we just have to hit that other 70% where the embie sticks around and grows. But to me progesterone supps are a blessing for people like me in order to even get pregnant. Gotta love science!

Thanks for responding Kati! I remember when your MC happened. Again, I'm so sorry. I really believe I have a LP defect that is not being addressed and that's why I am looking at a second opinion/new RE at this point. Even though we got PG on our first cycle with Clomid I can't shake the nagging suspicion my low P4 is partly to cause. Certainly, my other medical issues could come into play but I want to explore all avenues. And I agree, even though our PG ended in MC I wouldn't have traded that experiene for the world. Good luck in the future!

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