My just OB called with results of the quad screen and I have a 1/100 chance of having downs but its probably worse because of the EIF on the heart. So she said I need to decide about the amnio, she said she is comfortable doing it. She said if we don't do it we will be stressed the whole pg waiting to know whether LO has downs. She said that this pg has already been extremely stressful and will I be able to deal with the additional stress of not knowing. She also of course said another reason to do the test is whether we would medically abort. I'm leaning towards doing the Amnio because I feel like I will be badgered into it in the end and maybe its best to know. And if I do m/c then this pg wasn't meant to be.
Re: 1/100
I am sorry you are going through this. Any word yet on the fetal DNA sampling results? In the absence of those results, I'd go for the amnio, it is just super annoying that you haven't been able to get valid results from the fetal DNA sampling since it
IVF #1 = BFN
FET #1 = BFN
FET #2 = BFN
IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
IVF #3 = c/p 5w2d
Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
~~
TTC again March 2014
FET #3 - May/June 2014 - all embryos arrested before xfer - back to the drawing board...
IVF #4 - July/August 2014
Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
1 Clomid/Ovidrel BFN May 2011
Natural cycle Aug 2011 BFP M/C 4 Weeks
1 IUI Sept 2011 BFP M/c 7 weeks
Provera Dec 2011 BFP M/C 3 Weeks
IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone)
Went to Beer Center- high tnf, low lad, implantation failure
Jan 2013 BFP
Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
Miracle Born August 2013 Premature
Yours doesn't have to be a sad story
IVF #1 = BFN
FET #1 = BFN
FET #2 = BFN
IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
IVF #3 = c/p 5w2d
Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
~~
TTC again March 2014
FET #3 - May/June 2014 - all embryos arrested before xfer - back to the drawing board...
IVF #4 - July/August 2014
** lurking **
Ive been following your story, so first off, hugs!
Is it possible for you to do materniT21 test? We came back with a 1/78 chance of downs. I had low papp-a and was told that can cause false positives. I also heard that it be
Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
1 Clomid/Ovidrel BFN May 2011
Natural cycle Aug 2011 BFP M/C 4 Weeks
1 IUI Sept 2011 BFP M/c 7 weeks
Provera Dec 2011 BFP M/C 3 Weeks
IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone)
Went to Beer Center- high tnf, low lad, implantation failure
Jan 2013 BFP
Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
Miracle Born August 2013 Premature
Yours doesn't have to be a sad story
I am so sorry you're going through all of this. I think I'd also opt for the amnio for peace of mind and because with Trisomy 21 often come heart issues, so if you were aware of that in advance then doctors could be prepared, too.
There are
DX: DH (30) severe MFI, severely low count & low motility
Me (32): all clear
Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test
Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
2nd SA 6/18/12: sample is "adequate for ICSI"
Plan: IVF/ICSI July 2012!
ER: 7/26/12. 15 eggs retrieved, all mature.
TESE/TESA/aspiration from epididymis, no motile sperm found
froze all eggs, the saga of praying for good sperm continues.
8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
SA 8/17/12: Zero sperm
SA 8/23/12: Zero sperm
9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
All 3 survived the thaw on 11/15/12!
FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
moving on to DS
DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
1st u/s 4/8/13 shows one gestational sac
2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
A/S 7/22/13: IT'S A BOY!!
PAIF/SAIF Always Welcome
[IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]
I have been following you as we'll. sending you well wishes and the best outcome for you and baby.
I am so, so sorry that you're going through this. Sending you so many ((hugs))
I honestly have no idea what I would do if I was in your situation, because there isn't really a right or wrong answer. It has to come from you and DH, and whatever
HSG: Right tube all clear, left tube inconclusive
3 failed Clomid Cylces
4/5 lap revealed blocked left tube, but right tube is open
April/May- 50 mg Clomid + Ovidrel + IUI #1= CANCELLED left ovary ovulating
June 1- 100 mg Clomid + Ovidrel + IUI #1 = BFN
June 28- 100 mg Clomid + Ovidrel + IUI #2 =BFP!
7/12 Beta #1= 14 Beta #2= >5 Chemical Pregnancy
July-Nov long break to recover emotionally and financially
Nov 24- 100 mg Clomid + Ovidrel + IUI #3= BFN
Jan 22- Gonal-F + Ovidrel + IUI# 4 = CANCELLED no response on right
IVF #1- Start stims 4/7, ER 4/20, 21R, 14F, 6 frosties, ET 4/25, 2 embryos transferred= BFN
FET #1- June 2012, Lurpon starts 5/27- CANCELLED
FET #1 take 2- August 2012, delayed until Sept-CANCELLED
FET #1 take 3- ET 10/11, 2 embryos transferred,= BFFN
FET #2- Transfer 12/4--Cancelled, no embies survived thaw
Next steps-- IVF #2 with new RE in March
HOLY SURPRISE BFP 2/15/13!!!! Beta 1- 286, Beta 2- 782, First Ultrasound 2/25- baby in uterus & all looks good!
I'm so sorry you're going through this.
I think it is best to know for certain what to expect. If your LO does have Downs then having the appropriate team available upon birth would be so helpful, if any issues arose and if there was any special
TTC #1 since 1/10
DX: Unexplained/??? MFI issues
Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013
Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal
Moving on to IVF.
IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy
Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14
After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.
"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."
Everybody is welcome!!!
I'm so sorry you're going through this, especially after waiting through all the inconclusive blood tests. I too would do the amnio. The risks associated with it are pretty low and I would go crazy wondering/worrying about it the rest of th
BFP on Cycle #8. Natural M/C at ~8 weeks
IUI #1 and #2 (8/12, 9/12)- 50 mg Clomid + Ovidrel = BFNs
IVF #1 (EPP) 13R/10M/9F, 5DT 1-4AA blast, beta #1-148, beta #2-322, 5 frosties!
I'm so so sorry you're going through this. ((Hugs)) I would definitely do the amnio if it were me because it is a pretty low risk of m/c and I would want to know, but again, that is MO.
Whatever you decide, just know we're here for you. You'll be
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB , 2nd u/s 146bpm
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
Me: 29, Mild DOR
DH: 31, SE mostly normal, 1st SE morph 5%, 2nd SE morph 15%...yeah!.
BFP July 2011, Natural MC August 2011.
3 cycles of 50mg Clomid = BFN
*New RE* Feb/Mar 2012 100 mg Clomid + Trigger + IUI = BFN
*3rd RE* April-June -Break Cycles begin prep for IVF by doing 2 Heparin injects daily....fun fun!
IVF #1 - ER 7/19, ET 7/24, 2 beautiful embies transferred. Beta 8/2 = BFN
*New RE...yes again* FET Nov 2012 with our lone ranger = BFFN
RE Suggests Trying IUI Again, Jan. 2013 IUI #2 =BFN
Feb. 2013 IUI #3 = BFP!!!, Beta #1 (15dpIUI) = 90, Beta #2 (17dpIUI) = 210, U/S Scheduled for 3/18
My Blog
3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!!!
My Blog: The Journey
TTC with PCOS since 4/2011
1500mg Metformin
4 Clomid cycles (3 cancelled) / 2 Clomid + Follistim + IUI cycles
10/2012 & 11/2012- Treatment break while waiting for new insurance to become effective.
IUI #3 in December... or not. Surprise BFP on 12/9/12!
12/10 Beta #1: 25, 12/13 Beta #2: 122, 12/17 Beta #3: 738
12/20 1st u/s, 12/27 2nd u/s with a heartbeat!, 1/3 3rd u/s & released from RE
EDD: 8/21/13