Pregnant after IF

1/100

My just OB called with results of the quad screen and I have a 1/100 chance of having downs but its probably worse because of the EIF on the heart. So she said I need to decide about the amnio, she said she is comfortable doing it. She said if we don't do it we will be stressed the whole pg waiting to know whether LO has downs. She said that this pg has already been extremely stressful and will I be able to deal with the additional stress of not knowing. She also of course said another reason to do the test is whether we would medically abort. I'm leaning towards doing the Amnio because I feel like I will be badgered into it in the end and maybe its best to know. And if I do m/c then this pg wasn't meant to be. 
6 m/c
Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
1 Clomid/Ovidrel BFN May 2011
Natural cycle Aug 2011 BFP M/C 4 Weeks
1 IUI Sept 2011 BFP M/c 7 weeks
Provera Dec 2011 BFP M/C 3 Weeks
DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
Went to Beer Center- high tnf, low lad, implantation failure
Nov/Dec 2012 LIT Treatment
Dec 12 Humira
Jan 2013 BFP
Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
Miracle Born August 2013 Premature

Yours doesn't have to be a sad story



image
image


Lilypie - (ugiy)


Re: 1/100

  • I am sorry you are going through this. Any word yet on the fetal DNA sampling results? In the absence of those results, I'd go for the amnio, it is just super annoying that you haven't been able to get valid results from the fetal DNA sampling since it

    IUIs #1-3 (1x unmedicated, 2x Clomid) = 2 BFNs, 1 m/c at 7w3d
    IUIs #4-6 (injects) = 3 BFNs
    IVF #1 = BFN
    FET #1 = BFN
    FET #2 = BFN
    IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
    IVF #3 = c/p 5w2d
    Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
    ~~
    TTC again March 2014
    FET #3 - May/June 2014
    -
    all embryos arrested before xfer - back to the drawing board...
    IVF #4 - July/August 2014 
    beta 1 (11dp3dt) 220, beta 2 (13dp3dt) 671, beta 3 (19dp3dt) 10762
  • imageblueberries8:

    I am sorry you are going through this. Any word yet on the fetal DNA sampling results? In the absence of those r

    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


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  • imageluvboston:
    imageblueberries
    IUIs #1-3 (1x unmedicated, 2x Clomid) = 2 BFNs, 1 m/c at 7w3d
    IUIs #4-6 (injects) = 3 BFNs
    IVF #1 = BFN
    FET #1 = BFN
    FET #2 = BFN
    IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
    IVF #3 = c/p 5w2d
    Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
    ~~
    TTC again March 2014
    FET #3 - May/June 2014
    -
    all embryos arrested before xfer - back to the drawing board...
    IVF #4 - July/August 2014 
    beta 1 (11dp3dt) 220, beta 2 (13dp3dt) 671, beta 3 (19dp3dt) 10762
  • I think that you are making the right choice with the information that you have been given.  I will keep you in my prayers.
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  • ** lurking **

    Ive been following your story, so first off, hugs!

    Is it possible for you to do materniT21 test? We came back with a 1/78 chance of downs. I had low papp-a and was told that can cause false positives. I also heard that it be

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  • (((Hugs)))  I'm sorry you are faced with these difficult decisions.  I will be thinking of you.  
    After 4.5 years our miracle IVF baby is here!
    Born 7/30/13
  • imageJezebell26:
    lurking Ive been following your story, so first off, hugs! Is it possible for you to do materniT21 test? We came back
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



    image
    image


    Lilypie - (ugiy)


  • I am so sorry you're going through all of this. I think I'd also opt for the amnio for peace of mind and because with Trisomy 21 often come heart issues, so if you were aware of that in advance then doctors could be prepared, too. 

    There are

    (Live in Europe) TTC since 1/2010
  • I have no advice since I am so early in the process but I just wanted to say that I am so sorry that you are going through all of this. I am hoping and praying for the best possible outcome for you. Huge hugs.
    TTC since June 2011
    DX: DH (30) severe MFI, severely low count & low motility
    Me (32): all clear
    Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
    Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test :(
    Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
    2nd SA 6/18/12: sample is "adequate for ICSI"
    Plan: IVF/ICSI July 2012!
    ER: 7/26/12. 15 eggs retrieved, all mature.
    TESE/TESA/aspiration from epididymis, no motile sperm found :(
    froze all eggs, the saga of praying for good sperm continues.
    8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
    Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
    SA 8/17/12: Zero sperm
    SA 8/23/12: Zero sperm
    9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
    All 3 survived the thaw on 11/15/12!
    FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
    moving on to DS
    DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
    DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
    1st u/s 4/8/13 shows one gestational sac
    2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
    3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
    A/S 7/22/13: IT'S A BOY!!
    PAIF/SAIF Always Welcome
    [IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]Image and video hosting by TinyPic
    BabyFruit Ticker
  • Lurking
    I have been following you as we'll. sending you well wishes and the best outcome for you and baby.
    TTC #1 Since January 2011 Dx: PCOS and Anovulatory April 2012 BFP! Beta 1 5/22 - 1,000+ Beta 2 5/24 - 3,009 1st u/s 6/5 - TWINS!!! A/S Reveals we are Team PURPLE!!! Baby Birthday Ticker Ticker image image image  12/27 - surprise BFP - due August 2014
  • imageluvboston:
    imageJezebell
    Warning No formatter is installed for the format bbhtml
  • I am so, so sorry that you're going through this. Sending you so many ((hugs))

    I honestly have no idea what I would do if I was in your situation, because there isn't really a right or wrong answer. It has to come from you and DH, and whatever

    TTC #1 since Oct 2009, Dx: Unexplained Infertility
    HSG: Right tube all clear, left tube inconclusive
    3 failed Clomid Cylces
    4/5 lap revealed blocked left tube, but right tube is open
    April/May- 50 mg Clomid + Ovidrel + IUI #1= CANCELLED left ovary ovulating
    June 1- 100 mg Clomid + Ovidrel + IUI #1 = BFN
    June 28- 100 mg Clomid + Ovidrel + IUI #2 =BFP!
    7/12 Beta #1= 14 Beta #2= >5 Chemical Pregnancy :(
    July-Nov long break to recover emotionally and financially
    Nov 24- 100 mg Clomid + Ovidrel + IUI #3= BFN
    Jan 22- Gonal-F + Ovidrel + IUI# 4 = CANCELLED no response on right
    IVF #1- Start stims 4/7, ER 4/20, 21R, 14F, 6 frosties, ET 4/25, 2 embryos transferred= BFN :(
    FET #1- June 2012, Lurpon starts 5/27- CANCELLED
    FET #1 take 2- August 2012, delayed until Sept-CANCELLED
    FET #1 take 3- ET 10/11, 2 embryos transferred,= BFFN
    FET #2- Transfer 12/4--Cancelled, no embies survived thaw :(
    Next steps-- IVF #2 with new RE in March
    HOLY SURPRISE BFP 2/15/13!!!! Beta 1- 286, Beta 2- 782, First Ultrasound 2/25- baby in uterus & all looks good!


    BabyFruit Ticker

  • I'm so sorry you're going through this.

    I think it is best to know for certain what to expect. If your LO does have Downs then having the appropriate team available upon birth would be so helpful, if any issues arose and if there was any special

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • I'm so sorry you're going through this, especially after waiting through all the inconclusive blood tests.  I too would do the amnio.  The risks associated with it are pretty low and I would go crazy wondering/worrying about it the rest of th

    TTC #1 7/10, Me (31)- Dx DOR (AMH 0.6); DH (30)- normal
    BFP on Cycle #8. Natural M/C at ~8 weeks
    IUI #1 and #2 (8/12, 9/12)- 50 mg Clomid + Ovidrel = BFNs
    IVF #1 (EPP) 13R/10M/9F, 5DT 1-4AA blast, beta #1-148, beta #2-322, 5 frosties! 
     image  image  
    image
  • I'm so so sorry you're going through this. ((Hugs)) I would definitely do the amnio if it were me because it is a pretty low risk of m/c and I would want to know, but again, that is MO.

    Whatever you decide, just know we're here for you. You'll be

    Oct 13 April Siggy: Bunnies
    The 33 Most Important Bunny GIFs On The Internet


    image

    DS born on 9/30/13 from IVF #1.2!
      Lilypie - (xNS5)
  • ((hugs))
    TTC #1 Since 4/2010, Cycle 30
    Positive for HLA-B27, I'm a mutant :p
    Testing - Me ok, gluten issue? DH - borderline count, low motility
    4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
    7/3, 7/31, 9/25 - IUI#2-4=BFN
    IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
    FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
    4/20-surprise BFP and another c/p 4w2d
    FET#2 7/16/12 - 2 blasts = BFN
    FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
    1st u/s 5w6d, one beautiful little HB :), 2nd u/s 146bpm
    baby girl born 5/10/13

    TTC#2 since 12/17/2014, Cycle 8
    Repeat Testing...FSH=12, AMH=3.8, AFC=28. 
    IUI#5 5/10/15- c/p?
    IVF#2 8/19/15 - cancelled due to cysts
    IVF#2 take two 10/2015 - 5 blasts frozen
    FET#4 12/11/2015 - BFN - 4 blasts remaining
    FET#5 2/18/16 - BFP!!!  Beta1-3, 126, 250, 745!!

    Image and video hosting by TinyPicLilypie Angel and Memorial tickers

    Tons of love and ((hugs)) to my IF sister NMscubagirl


  • I have also been following your story and just didn't know enough about it to comment.  But I want to let you know that we're here for you and your in my T's and P's.
    Happily married Since May 2008. TTC#1 Since May 2010.
    Me: 29, Mild DOR
    DH: 31, SE mostly normal, 1st SE morph 5%, 2nd SE morph 15%...yeah!.
    BFP July 2011, Natural MC August 2011.
    3 cycles of 50mg Clomid = BFN
    *New RE* Feb/Mar 2012 100 mg Clomid + Trigger + IUI = BFN
    *3rd RE* April-June -Break Cycles begin prep for IVF by doing 2 Heparin injects daily....fun fun!
    IVF #1 - ER 7/19, ET 7/24, 2 beautiful embies transferred. Beta 8/2 = BFN
    *New RE...yes again* FET Nov 2012 with our lone ranger = BFFN
    RE Suggests Trying IUI Again, Jan. 2013 IUI #2 =BFN
    Feb. 2013 IUI #3 = BFP!!!, Beta #1 (15dpIUI) = 90, Beta #2 (17dpIUI) = 210, U/S Scheduled for 3/18
  • Hugs.  I hope the amnio goes well.
  • Thinking of you.  
    Married 8/2008. IVF with PGD March 2013.
    3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
    3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
    4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!!!
    PPROM at 31w, delivery at 32 weeks of two beautiful girls
    image
  • I'm so sorry you're going through this and that you are faced with this difficult decision.  Sending you T&Ps.

    My Blog: The Journey
    Image and video hosting by TinyPicImage and video hosting by TinyPicimage
    TTC with PCOS since 4/2011
    1500mg Metformin
    4 Clomid cycles (3 cancelled) / 2 Clomid + Follistim + IUI cycles
    10/2012 & 11/2012- Treatment break while waiting for new insurance to become effective.
    IUI #3 in December... or not. Surprise BFP on 12/9/12!
    12/10 Beta #1: 25, 12/13 Beta #2: 122, 12/17 Beta #3: 738
    12/20 1st u/s, 12/27 2nd u/s with a heartbeat!, 1/3 3rd u/s & released from RE

    EDD: 8/21/13

    BabyFetus Ticker

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