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Progesterone Injection

JourneytoJoy07JourneytoJoy07 member
in Infertility

I keep watching the videos on YouTube to help me not be so scared, but I can't lie...I am so nervous.  Makes me almost feel sick.  I'd think after two fresh rounds of IVF injections wouldn't phase me...but this is so different from the subcutaneous shots!  The first 3 nights I do the shot I will be out of town and a close friend will be doing them who happens to be a former NICU nurse but has never done an injection like this!   Any advice would be so appreciated....

like what hurt less for you?  standing up/laying down?

ice before heating pad after?  what do I need to buy for my trip??

Thank you!!

Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
April 2012:Varicocele embolization
IVF #1 July 2012: BFN :( DH- Femara 90 days 
12/10/2012 Femara helped!
IVF# 2: Jan 2013 BFP, M/C 6weeks0days
5 frosties. 
IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
3 frosties
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Re: Progesterone Injection

  • chucktgirlchucktgirl member
    It's okay. You'll be fine after your first one. Yes, they are worse than sub q, but you can handle it. I preferred to stand with pigeon toes. It's not substantially more painful, just a longer injection that needs to be injected slowly, so more of a disco

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    My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

    PAIF/SAIF Welcome!
    Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins    .
    First natural PG 9/27/11; mc: 1/20/12
    First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
    IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
    ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
    IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
    ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
    IVF #3:     NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
    ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
    IVF #4:     (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
    ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
    ***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
    IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
    BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
    2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
    2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
    2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
    IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
    5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
    6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
    7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
    EDD 3/18/15!

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  • SophistikittySophistikitty member

    I didn?t ice or heat before the injection but used a heating pad after.  I found using a heating pad after really made a difference with the amount o


    ***SIGNATURE WARNING***


    TTC #1

    Me 42, DH 47

    Dx = AMA/DOR, MFI

    IVF/ICSI #1 = BFN

    IVF/ICSI #2 = BFP; early loss

    IVF/ICSI #3 (DE) = BFP; early loss

    FET = BFN

    IVF/ICSI #4 (DE w/ CCS) = BFP

    Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

    1st U/S @ 6w2d showed one perfect little heartbeat! 

    2nd U/S @ 7w2d. HB 132 & everything measuring on track.

    Our beautiful little girl arrived January 2015!


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  • djma81djma81 member
    It's ok you'll be fine. Just as chucktgirl said, it's just a longer shot so the discomfort lasts longer. I've done quite a few of these and some seem to hurt worse then others but its nothing that can't be tolerated. I would roll the syringe in my palms f
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  • mkepanthermkepanther member
    The first one is always the worst! I stuck the PIO in my bra for about 10 mins to warm it up.

    Leaned over the couch arm and put all my weight on the opposite leg of where the shot was going ie. weight on right leg if injection was in left che
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  • sweetpea2003sweetpea2003 member

    **picture warning**

    This post caught my eye.  I did both PIO injections for IVF and then I did P-17 injections (same needle, different kind of progesterone) from 16-36 weeks with my second pregnancy.

    You will be FINE.  My recommen

    Married 6/28/03

    Kate ~ 7/3/09 *** Connor ~ 11/11/10

    4 miscarriages: 2007, 2009, 2013, 2014

    *~*~*~*~*

    No more TTC for us. We are done, and at peace, as a family of 4.

    "Suffering has been stronger than all other teaching, and has taught me to understand what your heart used to be. I have been bent and broken, but – I hope – into a better shape.” — Charles Dickens

     

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  • jms1374jms1374 member

    I never really had any pain from the shot itself and never warmed it up--maybe my husband did before he gave the shot and I just never knew it. I found that putting all of my weight on the opposite leg from where the shot is going and leaving the other

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  • daiseydoodadaiseydooda member
    They are not so bad. I have become a pro. This is how I have been doing them. I lay on my side kinda in fetal position so I cant tense up. Do the injection, after I use a tennis ball and apply pressure rolling the ball on the injection site.Then heat a da






          


     TTC since 9/10 consult 1/12 All testing came back fine Diagnosed with Unexplained infertility -3 medicated IUI's All BFN IVF - ER 11/14 24R, 15M, 13F ET 11/19, BETA 11/28 BFFN --Next step FET in Jan ET scheduled for 1/24. Beta #1 350 Beta #2 735. U/S Hell. miscarriage D&C at 9weeks. FET #2 ET 5/28 cancelled FET# 2.5 6/26 ET Beta 7/5 302 7/7 Beta #2 632 Everyone welcome



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  • runninggirljw82runninggirljw82 member

    You will be fine and do great!   :)  I've been doing them for about 3 1/2 weeks now.  The worst one for me was the first because it was the unknown.  I stand up and lean on the opposite leg that i'm injecting.  No ice/no h

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  • JSM0801JSM0801 member
    You got some good advice here and will do great! It's really not nearly as bad as the anxiety leading up to it. I told my nurse I was petrified, so they had me use ethly oleate, because it is thinner and goes in easier. I warmed it up in a heating pad fir
             

            

    *****Siggy/Ticker Warning*****

     Me (34)- no issues found MH (36)- MFI due to Vericocele. Straight to IVF w/ICSI 9/12, Antagonist. 9R, 7M, 5F = BFN c/p,  New RE for IVF #2- 1/13., Long Lupron. ER on 1/22 -10R, 9M, 9F. Transfer on hold due to overstimming. FET in Feb. 2 frozen blasts. Another BFN & another c/p. RPL testing all negative besides MTHFR gene, vericocle repair surgery 4/12/13-Bilateral Grade 3 Vericocele found & fixed, IVF #3 with PGS  4/13- 11R, 9M, 9F. Transferred 2 normal=BFN, 3 normal on ice. CCRM-here we come! ODWU-All test results normal. EPP in August. 21R, 20M, 19F. 12 blasts biopsied & frozen for CCS testing. Results showed 11 normal! FET Oct. 30. 2 5d 4AA blasts transferred. First ever BFP!!! Beta 1=216, Beta 2=870 1st U/S=It's TWINS!!! It's a BOY and a GIRL!! Everyone Welcome!!! 
                                       Image and video hosting by TinyPic Image and video hosting by TinyPic

                         Pregnancy Ticker
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  • JourneytoJoy07JourneytoJoy07 member
    imageSophistikitty:

    I didn?t ice

    Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
    April 2012:Varicocele embolization
    IVF #1 July 2012: BFN :( DH- Femara 90 days 
    12/10/2012 Femara helped!
    IVF# 2: Jan 2013 BFP, M/C 6weeks0days
    5 frosties. 
    IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
    3 frosties
    Report Reply
  • JourneytoJoy07JourneytoJoy07 member
    imagesweetpea2003:

    **picture warning**

    This post caught my eye.  I did both PIO injections for IVF and then I did P-17 i

    Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
    April 2012:Varicocele embolization
    IVF #1 July 2012: BFN :( DH- Femara 90 days 
    12/10/2012 Femara helped!
    IVF# 2: Jan 2013 BFP, M/C 6weeks0days
    5 frosties. 
    IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
    3 frosties
    Report Reply
  • JourneytoJoy07JourneytoJoy07 member
    Thank you all for the encouragement!  Nothing is impossible with God and I have again and again surprised myself by the strength I demonstrate because of my strong desire to have a child!!  Love to u all!
    Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
    April 2012:Varicocele embolization
    IVF #1 July 2012: BFN :( DH- Femara 90 days 
    12/10/2012 Femara helped!
    IVF# 2: Jan 2013 BFP, M/C 6weeks0days
    5 frosties. 
    IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
    3 frosties
    Report Reply
  • rlk2rlk2 member
    The two different size needles is to use one to draw the medicine up with and then you change the needle to inject with (this helps keep the needle sharp so its not as bad going in!).  You will do fine.  I also had DH do my shots leaning all my
    TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each)
    IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
    FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
    IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt.   Beta hell.  #1 2.5, #2 2.2- BFFFN! REALLY?
    IVF #3: ER 12/1 and only 2 retrieved.  1 fertilized with ICSI.  Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
    IVF #4: Antagonist protocol with endometrial scratch day one of stims.  ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching!  No frosties but hoping we won't need it!  Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002!  THIS HAS GOT TO BE IT!!!!!!!!!!  First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!  
    ****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!  

    BRINLEY AND RILEY LONG.  Born November 20, 2014 at 32 wks 3 days.  4lbs7oz and 4lbs5oz.  1 month NICU time for "B's" and growing and feeding.  Now healthy, thriving, beautiful little girls!
     imagehttp://i62.tinypic.com/2dl9ap0.jpgpghttp://oi61.tinypic.com/o7t1y0.jpg

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  • SophistikittySophistikitty member
    imageJourneytoJoy07:
    imageSophis


    ***SIGNATURE WARNING***


    TTC #1

    Me 42, DH 47

    Dx = AMA/DOR, MFI

    IVF/ICSI #1 = BFN

    IVF/ICSI #2 = BFP; early loss

    IVF/ICSI #3 (DE) = BFP; early loss

    FET = BFN

    IVF/ICSI #4 (DE w/ CCS) = BFP

    Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. 

    1st U/S @ 6w2d showed one perfect little heartbeat! 

    2nd U/S @ 7w2d. HB 132 & everything measuring on track.

    Our beautiful little girl arrived January 2015!


    Report Reply
  • JourneytoJoy07JourneytoJoy07 member
    imageSophistikitty:
    imageJourney
    Me:28, DH:30 Married: 07/07/07 TTC Since: March 2011 MFI Me: Possible PAI-1
    April 2012:Varicocele embolization
    IVF #1 July 2012: BFN :( DH- Femara 90 days 
    12/10/2012 Femara helped!
    IVF# 2: Jan 2013 BFP, M/C 6weeks0days
    5 frosties. 
    IVF #3 FET April 2013 BFP, M/C 7 weeks 0 days. 
    3 frosties
    Report Reply
  • BrideJackie11BrideJackie11 member
    I too did it laying face down on the couch.  I had DH count down 3-2-1 and when he got to one I would squeeze a tight fist (like fingernails into palm) to distract myself of the needle stick.  I was told not to ice for long if I did but I choose

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


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  • futurehuberfuturehuber member
    I'm glad you asked this, these are great tips. I'm really nervous about this one, especially since DH might be traveling a lot for work while I'm on PIO. Luckily I have friends/fam willing to help.  GL with your injections!
    TTC #1 since Sept 2011
    Me: 33, DH: 35, DX: PCOS & MFI (low everything)
    IUI #1-3 - Low Post-Wash Counts - All BFNs
    IVF #1 w/ ICSI: Long Lupron Protocol - Freeze-All Cycle due to Severe OHSS
    ER 4/27, 33 Eggs Retrieved, 13 Frosties
    FET #1 6/5, Transferred One Perfect 4AA Blast, HPT BFP @ 6dp5dt
    Beta #1 - 209, Beta #2 - 508, Beta #3 - 1,059
    EDD 2/20/14
    imageimage
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