XP: WTF appt. etc... opinions appreciated (long, sorry)

Sophistikitty · April 2013

I am trying my best to come to terms with our loss but am really having difficulty figuring out where things went wrong.

Quick summary: My clinic has a 63% live birth rate for DE in 2011. Our donor stimmed for 8 days (a little short but RE doesn?t think that is the issue). Out of the 12 mature eggs retrieved 8 fertilized with ICSI, 4 made it to blast. The two that were transferred were ?excellent quality? (they do not use a number system) and I was given a 70% pregnancy probability with a 40% chance of twins. Our donor has had two prior successful pregnancies, two freeze all cycles, and one cycle that resulted in m/c which we were told was due to a sperm issue.

DH has had sperm issues in the past. When we started this journey many moons ago our dx was male factor as he had 6% morphology. After consulting urologists and faithfully taking supplements (which he is still on) his SA was brought into normal range. The last DNA frag test he had was last April but at that point his fragmentation was 22.2%. Our RE does not seem to think that he is the issue but of course admits that it is possible. He seems to feel that there is something going on with me. Right away I pointed to my fibroid and adenomyosis. Again, like I have been told by several other RE?s, he does not feel the location of the fibroid is a concern and he feels that adenomyosis only contributes to failures when it causes a thin lining ? mine was 13mm at transfer. He seems to think there is something going on autoimmune wise. This is where I am getting really perplexed. I have had NK cell testing, ANA testing, anti-cardiolipin testing, lupus anticoagulant testing etc. and everything came back in the normal range. Part of me wonders if something went wrong with the cycle that I am just not seeing and pointing to me is the easiest out. Am I being too cynical? There were two points in the cycle where my clinic made errors. The first one was they did not go over the instructions with our donor regarding when she was supposed to stop BCP which resulted in her staying on BCP five days longer than scheduled. The second mistake (a big one) was by the same nurse who ?forgot? to check off PGS (which we had paid for) on our lab slip. Maybe we would have some answers had that not happened.

I guess I just want to know what your thoughts are and what your next steps would be if you were in my position. We have two frosties and I want to make sure I leave no stone unturned before considering transferring them.

What are the ideal E2 and P4 ranges after a positive beta in a DE or FET cycle? My E2 was over 2300 at 12dp5dt and then over 2600 15dp5dt. P4 was 46. For some reason I feel the E2 was high.

Thank you for reading if you got through all that! Hugs to everyone!

jcath · April 2013

I'm sorry for your loss. I don't have any advice just didn't want to read and not respond ((hugs))

MrsT4 · April 2013

First, I wanted to say that I'm very sorry for your losses. Big ((HUGS)) to you.

Not to minimize anyone else's failures, but I honestly feel that DE failures are a special kind of hell, especially after all of the emotional and finanicial

BeckyP005 · April 2013

I wish I had some sort of advice to help you out but I don't. Big hugs and I really hope you find some answers. Good luck to you

happywifemomofone · April 2013

I'm so sorry for you loss and understand your quest to find answers before you move forward with transferring your remaining frosties. I would probably seek a second or third opinion until you feel comfortable to decide to seek treatment or roll

Sophistikitty · April 2013

Thank you ladies. I really appreciate your input and support.

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XP: WTF appt. etc... opinions appreciated (long, sorry)

Re: XP: WTF appt. etc... opinions appreciated (long, sorry)

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