? from IF: Were you a poor responder?

Kathy4678 · February 2013

Hi Ladies-

I'm in the 2ww from IVF #1, and I'm not super hopeful. I had all normal CD3 bw- we did IVF due to severe MFI. My AMH was borderline low at just over 1, but my FSH and AFC was normal. When I started stims- my e2 rose VERY slowly and I only got 4 eggs at retrieval.

So in a nutshell- I'm just trying to do a little research and see if there are other protocols that work better for poor responders. So if this was you- tell me what worked for you. Thanks!

Dragonfly1226 · February 2013

I don't have any experience, but I wanted to say that sometimes it is the cycles when everything seems to go wrong that you get a BFP. Good luck hon!

Kathy4678 · February 2013

Dragonfly1226:
I don't have any experience, but I wanted to say that sometimes it is the cycles when everything seems to go wrong that you get a BFP. Good luck hon!

Well that would be this one FO SHO! It was a hot hot mess. Thank you!

ashleymarie512 · February 2013

I was a very poor responder to every cycle except this last one. We did Clomid, Femara and a few cycles of injectables before finding one that would take me past the CD8 monitoring appt. What worked for me was 225 of Menopur, 225 of Follistim. I ended up over responding and we had to convert from hopeful IUI to IVF. We retrieved 23 eggs, 15 fertilized and had 6 to freeze. Good luck, I totally get how frustrating it is to go through all this emotion, time, money and have it cancelled or not go as planned. Take care!!

ELF4321 · February 2013

Replied on PAIF. I really need to stop lurking so much on the other boards! LOL

itsmevkb · February 2013

My doctor assumed, correctly, that I would be a poor responder and he used a lupron flare protocol for my IVF. I was on maximum dosages of stims and had seven eggs retrieved. I'm sorry you didn't get more eggs retrieved but try and remember that it only takes one. My IVF was back in 2008 so I don't remember all the specifics but I believe most of them are in my blog (link in my siggy).

oooCarrieB · February 2013

I failed the clomid challenge, basically no response and ended up w an FSH of 24 on day 10, dx as DOR. so RE assumed I would be a poor responder to the IVF meds.

I really credit doing acupuncture and following the infertility cure diet to helping me respond better than expected to the meds during IVF. Also I did antagonist protocol w bcps.

Good luck. Like pp said, it only takes one!

Ruthie04 · February 2013

I had a REALLY crappy response to the antagonist protocol. That cycle went so poorly we ended up canceling because my RE thought there was a decent chance my eggs would be so fried, we would end up with a 0% fert rate. D**n dominant follicle killed my cycle. Next time, I did a Stop Lupron protocol with 15 units of Lupron and a starter dose of 150 Follistim/ 150 Menopur. It took me a really long time to "wake up" from Lupron, but we ended up with 12 mature eggs. On my next cycle, I was on 10 units of Lupron and 450 total of Follistim and Menopur. My AFC at baseline was six. In the end, I got 17 eggs; 16 fertilized. I read somewhere that CC.RM doesn't do Stop Lupron because of the low pregnancy rates, but we had success. However, I credit a lot of my success to pre/post transfer acu (my first transfer was very painful and I had super intense cramps after), assisted hatching, and a change to PIO (I think I had absorption issues on Endometrin).

Anyway, I hope you don't need this information! Best of luck with your current cycle!

Ash1103 · February 2013

I was a poor responder on my first ivf try.my eggs were not growing and I was maxed out with meds dosage, At retrievel I had 9 retrieved, 7 fertilized and 2 transferred with none to freeze and I'm now 11 weeks pregnant. I was not hopeful at all during my 2ww. Then I got a call with the best news possible, keep the faith bc miracles do happen!!!

kbeach82 · February 2013

I have DOR (DH also has severe MFI). I was on the Long Lupron protocol for my first IVF (my DOR dx is fairly recent). Lupron was stopped completely at some point when my RE realized I was being oversuppresed and all of my meds were increased. Stimmed for 13 or 14 days, had 5 eggs retrieved, 4 were mature, and 3 fertilized normally w/ICSI. We did a 3dt of 2 embies that resulted in the birth of our son.

IVF #2 was Microdose Lupron Flare. Stimmed at the max doses of my meds for 12 days, had 6 eggs retrieved, 5 of which were mature, and 4 fertilized normally w/ICSI. We still had all 4 embies growing by day 5, and ended up transferring 2. I am 26 weeks pregnant with twins, and we have 1 frozen embryo.

My RE always stresses quality over quantity, and that has been the ticket for us with our IVF cycles. Good luck to you!

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